Please Wait
Applying Filters...
menu
    • menu
    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    Polpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.

    Virtual Booth

    Contact Supplier

    Chirogate is a professional Prostaglandin manufacturer.

    Virtual Booth

    Contact Supplier

    Farmak works in the development, production and marketing of APIs, Intermediates & Specialties// FDA inspected.

    Virtual Booth

    Contact Supplier

    Skyepharma, an Expert and Innovative CDMO Partner for tailor-made solutions in complex oral solids and bioproduction.

    Virtual Booth

    Contact Supplier

    jdmfs-not-supported-m-2025-06-30

    Virtual Booth

    An Enquiry

    Menu

    JNJ-6379

    DEVELOPMENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: Unii-2456kw2166, Bersacapavir [inn], Bersacapavir [usan], Jnj-6379, Jnj-56136379, 1638266-40-6
    Molecular Formula
    C16H14F4N4O3S
    Molecular Weight
    418.4  g/mol
    InChI Key
    SBVBIDUKSBJYEF-VIFPVBQESA-N
    FDA UNII
    2456KW2166
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-(3-cyano-4-fluorophenyl)-1-methyl-4-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrrole-2-carboxamide
    2.1.2 InChI
    InChI=1S/C16H14F4N4O3S/c1-9(16(18,19)20)23-28(26,27)12-6-14(24(2)8-12)15(25)22-11-3-4-13(17)10(5-11)7-21/h3-6,8-9,23H,1-2H3,(H,22,25)/t9-/m0/s1
    2.1.3 InChI Key
    SBVBIDUKSBJYEF-VIFPVBQESA-N
    2.1.4 Canonical SMILES
    CC(C(F)(F)F)NS(=O)(=O)C1=CN(C(=C1)C(=O)NC2=CC(=C(C=C2)F)C#N)C
    2.1.5 Isomeric SMILES
    C[C@@H](C(F)(F)F)NS(=O)(=O)C1=CN(C(=C1)C(=O)NC2=CC(=C(C=C2)F)C#N)C
    2.2 Other Identifiers
    2.2.1 UNII
    2456KW2166
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Jnj-56136379

    2. Jnj-6379

    2.3.2 Depositor-Supplied Synonyms

    1. Unii-2456kw2166

    2. Bersacapavir [inn]

    3. Bersacapavir [usan]

    4. Jnj-6379

    5. Jnj-56136379

    6. 1638266-40-6

    7. 2456kw2166

    8. 1h-pyrrole-2-carboxamide, N-(3-cyano-4-fluorophenyl)-1-methyl-4-((((1s)-2,2,2-trifluoro-1-methylethyl)amino)sulfonyl)-

    9. N-(3-cyano-4-fluorophenyl)-1-methyl-4-(((2s)-1,1,1-trifluoro-2-propanyl)sulfamoyl)-1hpyrrole-2-carboxamide

    10. N-(3-cyano-4-fluorophenyl)-1-methyl-4-[[(2s)-1,1,1-trifluoropropan-2-yl]sulfamoyl]pyrrole-2-carboxamide

    11. Bersacapavir [who-dd]

    12. Chembl4744254

    13. Schembl17700943

    14. Ex-a5896

    15. Who 11272

    16. Hy-109168

    17. Cs-0116353

    2.4 Create Date
    2016-08-06
    3 Chemical and Physical Properties
    Molecular Weight 418.4 g/mol
    Molecular Formula C16H14F4N4O3S
    XLogP32.2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count5
    Exact Mass418.07227414 g/mol
    Monoisotopic Mass418.07227414 g/mol
    Topological Polar Surface Area112 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity730
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Antiviral Agents

    Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)