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    Technical details about DSSTox_CID_3497, learn more about the structure, uses, toxicity, action, side effects and more

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    DSSTox_CID_3497

    APIs // Active Pharmaceutical Ingredients

    INTERMEDIATES

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    PharmaCompass

    Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

    Temad- We think of world-class quality.

    2D Structure
    1. Also known as: 52549-17-4, Niflan, Pyranoprofen, 2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoic acid, Elicapric, Y-8004
    Molecular Formula
    C15H13NO3
    Molecular Weight
    255.27  g/mol
    InChI Key
    TVQZAMVBTVNYLA-UHFFFAOYSA-N
    FDA UNII
    2R7O1ET613
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
    2.1.2 InChI
    InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18)
    2.1.3 InChI Key
    TVQZAMVBTVNYLA-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    2R7O1ET613
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2-(5h-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic Acid

    2. Alpha-methyl-5h-(1)benzopyrano(2,3-b)pyridine-7-acetic Acid

    3. Niflan

    4. Nifran

    5. Oftalar

    6. Pyranoprofen

    7. Pyranoprofen, Methyl-14c-labeled

    8. Zaltoprofen

    2.3.2 Depositor-Supplied Synonyms

    1. 52549-17-4

    2. Niflan

    3. Pyranoprofen

    4. 2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoic Acid

    5. Elicapric

    6. Y-8004

    7. Nsc-759832

    8. 2-{5h-chromeno[2,3-b]pyridin-7-yl}propanoic Acid

    9. 2-(5h-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic Acid

    10. Chembl367463

    11. 2r7o1et613

    12. 2-(5h-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic Acid

    13. Ncgc00167980-01

    14. Dsstox_cid_3497

    15. Dsstox_rid_77055

    16. Dsstox_gsid_23497

    17. Pranoprofene

    18. Pranoprofeno

    19. Pranoprofenum

    20. Pranoprofen [inn:jan]

    21. Pranoprofene [inn-french]

    22. Pranoprofenum [inn-latin]

    23. Pranoprofeno [inn-spanish]

    24. Cas-52549-17-4

    25. Sr-05000001513

    26. Brn 0889798

    27. Pransus

    28. Unii-2r7o1et613

    29. Pranoprofen;

    30. Elicapric (tn)

    31. 2-(5h-(1)benzopyrano(2,3-b)pyridin-7yl)propionic Acid

    32. Alpha-methyl-5h-(1)-benzopyrano(2,3-b)pyridine-7-acetic Acid

    33. Alpha-methyl-5h-(1)benzopyrano(2,3-b)pyridine-7-acetic Acid

    34. Pranoprofen [mi]

    35. Pranoprofen [inn]

    36. Pranoprofen [jan]

    37. Pranoprofen (jp17/inn)

    38. Pranoprofen [mart.]

    39. Schembl26008

    40. Pranoprofen [who-dd]

    41. Dtxsid1023497

    42. Chebi:32040

    43. Pranoprofen, >=98% (hplc)

    44. (2s)-2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoic Acid

    45. Hms2090j03

    46. Hms3651g06

    47. Hms3714i03

    48. Hms3884o16

    49. Pharmakon1600-01502324

    50. 5h-(1)benzopyrano(2,3,-b)pyridine-7-acetic Acid, Alpha-methyl-

    51. Bcp11947

    52. Ex-a5741

    53. Hy-b0336

    54. Tox21_112601

    55. 5h-[1]benzopyrano[2,3-b]pyridine-7-acetic Acid, .alpha.-methyl-

    56. Ac-697

    57. Bdbm50286819

    58. Mfcd00866111

    59. Nsc759832

    60. S1960

    61. Akos015918442

    62. Tox21_112601_1

    63. Ccg-213822

    64. Db13514

    65. Nsc 759832

    66. Ncgc00167980-02

    67. As-12631

    68. Ft-0652901

    69. P2778

    70. Sw199147-2

    71. D01578

    72. F17350

    73. Ab01275517-01

    74. Ab01275517_02

    75. Ab01275517_03

    76. 2-(5h-chromeno[2,3-b]pyridin-7-yl)propanoicacid

    77. 549p174

    78. Q-201611

    79. Q7238394

    80. Sr-05000001513-1

    81. Sr-05000001513-2

    82. Brd-a64610707-001-01-0

    83. I2-(10h-9-oxa-1-aza-anthracen-6-yl)-propionic Acid

    84. 2-(5h-[1]benzopyrano-[2,3-b]pyridin-7-yl)propionic Acid

    85. .alpha.-methyl-5h-(1)benzopyrano(2,3-b)pyridine-7-acetic Acid

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 255.27 g/mol
    Molecular Formula C15H13NO3
    XLogP32.7
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count2
    Exact Mass255.08954328 g/mol
    Monoisotopic Mass255.08954328 g/mol
    Topological Polar Surface Area59.4 Ų
    Heavy Atom Count19
    Formal Charge0
    Complexity346
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Gout Suppressants

    Agents that increase uric acid excretion by the kidney (URICOSURIC AGENTS), decrease uric acid production (antihyperuricemics), or alleviate the pain and inflammation of acute attacks of gout. (See all compounds classified as Gout Suppressants.)

    Anti-Inflammatory Agents, Non-Steroidal

    Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

    4.2 ATC Code

    S01BC09

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    S - Sensory organs

    S01 - Ophthalmologicals

    S01B - Antiinflammatory agents

    S01BC - Antiinflammatory agents, non-steroids

    S01BC09 - Pranoprofen

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