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    Technical details about Dextrans, learn more about the structure, uses, toxicity, action, side effects and more

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    Dextrans

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    2D Structure
    Also known as: L3l3xyp7mp, Lmwd, Schembl206877, Chembl1697742, O-alpha-d-glucopyranosyl-(1.6)-o-alpha-d-glucopyranosyl-(1.6)-d-glucose, Hy-n0913a
    Molecular Formula
    C18H32O16
    Molecular Weight
    504.4  g/mol
    InChI Key
    FZWBNHMXJMCXLU-BLAUPYHCSA-N
    FDA UNII
    L3L3XYP7MP
    A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
    2.1.2 InChI
    InChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2/t5-,6+,7+,8+,9+,10+,11+,12+,13-,14-,15+,16+,17-,18-/m0/s1
    2.1.3 InChI Key
    FZWBNHMXJMCXLU-BLAUPYHCSA-N
    2.1.4 Canonical SMILES
    C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)O
    2.1.5 Isomeric SMILES
    C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OC[C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O)O)O)O)O)O)O)O
    2.2 Other Identifiers
    2.2.1 UNII
    L3L3XYP7MP
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Dextran

    2. Dextran 40000

    3. Dextran 70

    4. Dextran 75

    5. Dextran 80

    6. Dextran B 1355

    7. Dextran B 1355 S

    8. Dextran B-1355

    9. Dextran B-1355-s

    10. Dextran B1355

    11. Dextran B512

    12. Dextran Derivatives

    13. Dextran M 70

    14. Dextran T 40

    15. Dextran T 500

    16. Dextran T 70

    17. Dextran T-40

    18. Dextran T-500

    19. Dextrans

    20. Hemodex

    21. Hyskon

    22. Infukoll

    23. Macrodex

    24. Polyglucin

    25. Promit

    26. Rheodextran

    27. Rheoisodex

    28. Rheomacrodex

    29. Rheopolyglucin

    30. Rondex

    31. Saviosol

    2.3.2 Depositor-Supplied Synonyms

    1. L3l3xyp7mp

    2. Lmwd

    3. Schembl206877

    4. Chembl1697742

    5. O-alpha-d-glucopyranosyl-(1.6)-o-alpha-d-glucopyranosyl-(1.6)-d-glucose

    6. Hy-n0913a

    7. Dtxsid701317190

    8. 6-.alpha.-isomaltosylglucose

    9. Zinc64622163

    10. Cs-0109495

    11. D-glucose, O-.alpha.-d-glucopyranosyl-(1->6)-o-.alpha.-d-glucopyranosyl-(1->6)-

    12. O-alpha-d-glucopyranosyl-(1-->6)-o-alpha-d-glucopyranosyl-(1-->6)-d-glucose

    13. Wurcs=2.0/2,3,2/[o2122h][a2122h-1a_1-5]/1-2-2/a6-b1_b6-c1

    14. (2r,3s,4r,5r)-2,3,4,5-tetrahydroxy-6-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-((((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy)methyl)oxan-2-yl)oxy)hexanal

    2.4 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 504.4 g/mol
    Molecular Formula C18H32O16
    XLogP3-7.2
    Hydrogen Bond Donor Count11
    Hydrogen Bond Acceptor Count16
    Rotatable Bond Count11
    Exact Mass504.16903493 g/mol
    Monoisotopic Mass504.16903493 g/mol
    Topological Polar Surface Area277 Ų
    Heavy Atom Count34
    Formal Charge0
    Complexity625
    Isotope Atom Count0
    Defined Atom Stereocenter Count14
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anticoagulants

    Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)

    Plasma Substitutes

    Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration. (See all compounds classified as Plasma Substitutes.)

    4.2 FDA Pharmacological Classification
    4.2.1 Pharmacological Classes
    Osmotic Activity [MoA]; Plasma Volume Expander [EPC]; Increased Intravascular Volume [PE]
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