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    Technical details about Cyclopentolate Hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more

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    Cyclopentolate Hydrochloride

    APIs // Active Pharmaceutical Ingredients

    PRICE INFORMATION

    DOSSIERs // Finished Dosage Forms

    DRUG PRODUCT COMPOSITION

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    DIGITAL CONTENT

    PharmaCompass

    Inke S.A: APIs manufacturing plant.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    1. Also known as: 5870-29-1, Cyclopentolate hcl, Cyplegin, Cyclogyl, 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate hydrochloride, Ak-pentolate
    Molecular Formula
    C17H26ClNO3
    Molecular Weight
    327.8  g/mol
    InChI Key
    RHKZVMUBMXGOLL-UHFFFAOYSA-N
    A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;hydrochloride
    2.1.2 InChI
    InChI=1S/C17H25NO3.ClH/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17;/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3;1H
    2.1.3 InChI Key
    RHKZVMUBMXGOLL-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O.Cl
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Cyclogyl

    2. Cyclopentolate

    2.2.2 Depositor-Supplied Synonyms

    1. 5870-29-1

    2. Cyclopentolate Hcl

    3. Cyplegin

    4. Cyclogyl

    5. 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate Hydrochloride

    6. Ak-pentolate

    7. Mydrilate

    8. Pentolair

    9. Cyclopentolate (hydrochloride)

    10. Cyclopentolatehcl

    11. 5870-29-1 (hcl)

    12. Mls000069583

    13. Chebi:4025

    14. Beta-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate Hydrochloride

    15. 2-(dimethylamino)ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate Hydrochloride

    16. 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;hydrochloride

    17. Cyclopentolate For System Suitability

    18. Cylate

    19. Nsc-756706

    20. 60452-44-0

    21. Akpentolate

    22. Smr000058810

    23. Zyklolat

    24. 60452-46-2

    25. 2-(dimethylamino)ethyl (+-)-1-hydroxy-alpha-phenylcyclopentaneacetate Hydrochloride

    26. Dsstox_cid_25390

    27. Dsstox_rid_80847

    28. Dsstox_gsid_45390

    29. Cicloplegicedol

    30. Ciclolux

    31. Skiacol

    32. Alnide

    33. 0uxd5v5g6v

    34. 6d6x07d6bn

    35. Tsiklopentolat Hydrochloride;cyclogyl Hydrochloride;dl-cyclopentolate Hydrochloride

    36. Benzeneacetic Acid, Alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride, (-)-

    37. Cyclopentolate Hydrochloride, (+)-

    38. Cyclopentolate Hydrochloride, (-)-

    39. 736i6971te

    40. Einecs 227-521-8

    41. Sr-01000003121

    42. Unii-736i6971te

    43. Cyclogyl (tn)

    44. Cyclopentolate Hydrochloride [usp:jan]

    45. Opera_id_69

    46. Ncgc00016661-01

    47. (+-)-cyclopentolate Hcl

    48. Unii-0uxd5v5g6v

    49. 2-(2-(1-hydroxycyclopentyl)-2-phenylacetoxy)ethyldimethylammonium Chloride

    50. Cas-5870-29-1

    51. Crimson Glory Rose Resinoid

    52. Unii-6d6x07d6bn

    53. Schembl24612

    54. Mls001148637

    55. Mls001332539

    56. Mls001332540

    57. Spectrum1500212

    58. Regid_for_cid_22162

    59. Cyclopentolate Hcl;ak-pentolate

    60. Chembl1200473

    61. Dtxsid9045390

    62. Hy-b1621a

    63. Hms1571k12

    64. Hms1920a22

    65. Pharmakon1600-01500212

    66. Amy23400

    67. Bcp21337

    68. Einecs 262-240-4

    69. Einecs 262-242-5

    70. Tox21_110550

    71. Ccg-39635

    72. Mfcd00079048

    73. Nsc756706

    74. S5921

    75. 2-(dimethylamino)ethyl (+)-(1-hydroxycyclopentyl)phenylacetate Hydrochloride

    76. Akos015901379

    77. Tox21_110550_1

    78. Nsc 756706

    79. Benzeneacetic Acid, Alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride

    80. Cyclopentaneacetic Acid, 1-hydroxy-alpha-phenyl-, 2-(dimethylamino)ethyl Ester, Hydrochloride

    81. Cyclopentolate Hydrochloride (jp17/usp)

    82. Ncgc00018213-06

    83. Ncgc00094635-01

    84. Ncgc00094635-02

    85. Ncgc00094635-03

    86. Ncgc00094635-04

    87. Ac-27486

    88. As-49330

    89. Benzeneacetic Acid, Alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride, (+-)-

    90. Db-053247

    91. Cs-0013554

    92. Ft-0603161

    93. D01002

    94. H10247

    95. 870c291

    96. Sr-01000003121-4

    97. Q27266147

    98. 2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate Hydrochloride

    99. Cyclopentolate Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    100. 2-(dimethylamino)ethyl (-)-(1-hydroxycyclopentyl)phenylacetate Hydrochloride

    101. 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;hydron;chloride

    102. 2-dimethylaminoethyl 1-hydroxy-

    103. A-phenylcyclopentaneacetate,cyclopentolate Hydrochloride

    104. Alpha-(1-hydroxycyclopentyl)benzeneacetic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

    105. Cyclopentolate For System Suitability, European Pharmacopoeia (ep) Reference Standard

    106. Cyclopentolate Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    107. Benzeneacetic Acid, .alpha.-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride (1:1)

    108. Benzeneacetic Acid,

    109. A-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride, (-)-

    2.3 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 327.8 g/mol
    Molecular Formula C17H26ClNO3
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass327.1601214 g/mol
    Monoisotopic Mass327.1601214 g/mol
    Topological Polar Surface Area49.8 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity331
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameAkpentolate
    Active IngredientCyclopentolate hydrochloride
    Dosage FormSolution/drops
    RouteOphthalmic
    Strength1%
    Market StatusPrescription
    CompanyAkorn

    2 of 4  
    Drug NamePentolair
    Active IngredientCyclopentolate hydrochloride
    Dosage FormSolution/drops
    RouteOphthalmic
    Strength1%
    Market StatusPrescription
    CompanyBausch And Lomb

    3 of 4  
    Drug NameAkpentolate
    Active IngredientCyclopentolate hydrochloride
    Dosage FormSolution/drops
    RouteOphthalmic
    Strength1%
    Market StatusPrescription
    CompanyAkorn

    4 of 4  
    Drug NamePentolair
    Active IngredientCyclopentolate hydrochloride
    Dosage FormSolution/drops
    RouteOphthalmic
    Strength1%
    Market StatusPrescription
    CompanyBausch And Lomb

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Muscarinic Antagonists

    Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)

    Parasympatholytics

    Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

    Mydriatics

    Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics. (See all compounds classified as Mydriatics.)

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