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    Technical details about Alpharma brand of buflomedil hydrochloride, learn more about the structure, uses, toxicity, action, side effects and more

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    Alpharma brand of buflomedil hydrochloride

    APIs // Active Pharmaceutical Ingredients

    DOSSIERs // Finished Dosage Forms

    GLOBAL SALES INFORMATION

    MARKET PLACE

    ANALYTICAL SOLUTION(s)

    PharmaCompass

    Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    Also known as: Buflomedil hcl, 35543-24-9, Fonzylane, Loftyl, Buflomedil (hydrochloride), 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride
    Molecular Formula
    C17H26ClNO4
    Molecular Weight
    343.8  g/mol
    InChI Key
    ZDPACSAHMZADFZ-UHFFFAOYSA-N
    FDA UNII
    3J944AFS8S
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one;hydrochloride
    2.1.2 InChI
    InChI=1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H
    2.1.3 InChI Key
    ZDPACSAHMZADFZ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    COC1=CC(=C(C(=C1)OC)C(=O)CCCN2CCCC2)OC.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    3J944AFS8S
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2,4,6-trimethoxyphenyl-3-pyrrolidine Propyl Ketone

    2. Blufomedil

    3. Bufedil

    4. Buflo 1a Pharma

    5. Buflo Abz

    6. Buflo-pos

    7. Buflo-puren

    8. Buflohexal

    9. Buflomedil

    10. Buflomedil Heumann

    11. Buflomedil Lindo

    12. Buflomedil Pyridoxal Phosphate

    13. Buflomedil Stada

    14. Buflomedil Von Ct

    15. Buflomedil-ratiopharm

    16. Bufomedil

    17. Fonzylane

    18. Ll 1656

    19. Lofton

    20. Loftyl

    21. Sinoxis

    2.3.2 Depositor-Supplied Synonyms

    1. Buflomedil Hcl

    2. 35543-24-9

    3. Fonzylane

    4. Loftyl

    5. Buflomedil (hydrochloride)

    6. 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone Hydrochloride

    7. Mls000028735

    8. 3j944afs8s

    9. Bufedil

    10. Nsc-759291

    11. Irrodan

    12. Smr000058803

    13. Lofton

    14. 4-(pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one Hydrochloride

    15. Dsstox_cid_26977

    16. Dsstox_rid_82032

    17. Dsstox_gsid_46977

    18. Buflocit

    19. Buflan

    20. Irrodan R

    21. Buflomedil Hydrochloride [jan]

    22. Sr-01000721839

    23. Ncgc00016831-01

    24. Cas-35543-24-9

    25. Ll 1656

    26. Unii-3j944afs8s

    27. 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one;hydrochloride

    28. Prestwick_782

    29. Einecs 252-611-9

    30. Mfcd00078965

    31. Opera_id_262

    32. Bucladesine (calcium Salt)

    33. A-48257

    34. Buflomedil Hydrochloride,(s)

    35. Mls001148174

    36. Mls001401458

    37. Mls002222262

    38. Mls006010627

    39. Schembl211907

    40. Chembl1715107

    41. Dtxsid6046977

    42. Buflomedil For Peak Identification

    43. Hms1569e14

    44. Pharmakon1600-01505992

    45. Bcp13305

    46. Hy-b0484

    47. Tox21_110636

    48. Tox21_301435

    49. 4-(1-pyrrolidyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone Hydrochloride

    50. Buflomedil Hydrochloride [mi]

    51. Nsc759291

    52. S2607

    53. Akos015962015

    54. Chlorhydrate De (trimethoxy-2-4-6) Phenyl-(pyrrolidine-3) Propylacetone

    55. Tox21_110636_1

    56. Ab03021

    57. Ccg-100878

    58. Ds-9078

    59. Nc00128

    60. Nsc 759291

    61. Buflomedil Hydrochloride [mart.]

    62. Chlorhydrate De (trimethoxy-2-4-6) Phenyl-(pyrrolidine-3) Propylacetone [french]

    63. Buflomedil Hydrochloride [who-dd]

    64. Ncgc00016831-06

    65. Ncgc00180961-01

    66. Ncgc00256242-01

    67. Ac-15509

    68. B3647

    69. Buflomedil Hydrochloride, Analytical Standard

    70. Ft-0623281

    71. Sw196920-4

    72. Buflomedil Hydrochloride [ep Monograph]

    73. 543b249

    74. Q-200766

    75. Sr-01000721839-4

    76. Sr-01000721839-5

    77. Q27257293

    78. Buflomedil Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

    79. Buflomedil Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    80. 1-butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-, Hydrochloride

    81. Buflomedil For Peak Identification, European Pharmacopoeia (ep) Reference Standard

    2.4 Create Date
    2006-04-14
    3 Chemical and Physical Properties
    Molecular Weight 343.8 g/mol
    Molecular Formula C17H26ClNO4
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count8
    Exact Mass343.1550360 g/mol
    Monoisotopic Mass343.1550360 g/mol
    Topological Polar Surface Area48 Ų
    Heavy Atom Count23
    Formal Charge0
    Complexity330
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Vasodilator Agents

    Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

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