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    Technical details about 2-Dodecoxyethanol, learn more about the structure, uses, toxicity, action, side effects and more

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    2-Dodecoxyethanol

    DOSSIERs // Finished Dosage Forms

    MARKET PLACE

    PharmaCompass

    Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    2D Structure
    Also known as: 4536-30-5, Ethylene glycol monododecyl ether, 2-dodecoxyethanol, Ethanol, 2-(dodecyloxy)-, Lauryl ethoxylate, Laureth-1
    Molecular Formula
    C14H30O2
    Molecular Weight
    230.39  g/mol
    InChI Key
    SFNALCNOMXIBKG-UHFFFAOYSA-N
    FDA UNII
    J89TKQ5R54
    An alkyl polyglycol ether of LAURYL ALCOHOL, chemically defined as an alcohol ethoxylate having an average alkyl chain of 12??14 carbon atoms, and an ethylene oxide chain of 9 ethylene oxide units. It is used as a detergent, and medically as a local anesthetic, and as a sclerosing agent for the treatment of ESOPHAGEAL AND GASTRIC VARICES and VARICOSE VEINS.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-dodecoxyethanol
    2.1.2 InChI
    InChI=1S/C14H30O2/c1-2-3-4-5-6-7-8-9-10-11-13-16-14-12-15/h15H,2-14H2,1H3
    2.1.3 InChI Key
    SFNALCNOMXIBKG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCCCCCCCCCCCOCCO
    2.2 Other Identifiers
    2.2.1 UNII
    J89TKQ5R54
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Aethoxysclerol

    2. Aethoxysklerol

    3. Aetoxisclerol

    4. Alpha-dodecyl-omega-hydroxypoly(oxy-1,2ethanediyl)

    5. Atossisclerol

    6. Atoxysclerol

    7. Brij 30

    8. Brij-30

    9. Brij30

    10. Dodecyl Ethyleneglycol Monoether

    11. Dodecyl Ethyleneglycol Monoethers

    12. Ether, Nonaethyleneglycol Monododecyl

    13. Ether, Polyethylene Glycol-7-lauryl

    14. Ether, Polyoxyethylene 9-lauryl

    15. Ether, Polyoxyethylene Lauryl

    16. Ether, Polyoxyethylene-4-dodecyl

    17. Ether, Tetraethyleneglycol Lauryl

    18. Ethoxysclerol

    19. Ethyleneglycol Monoether, Dodecyl

    20. Hydroxypolyethoxydodecane

    21. Laureth

    22. Laureth 1

    23. Laureth 4

    24. Laureth 7

    25. Laureth 9

    26. Laureth-1

    27. Laureth-4

    28. Laureth-7

    29. Laureth-9

    30. Laureths

    31. Lauromacrogol

    32. Lauromacrogol 400

    33. Lauromacrogols

    34. Lauryl Ether, Tetraethyleneglycol

    35. Lubrol 12a9

    36. Lubrol Px

    37. Lubrol-px

    38. Monododecyl Ether, Nonaethyleneglycol

    39. Monoether, Dodecyl Ethyleneglycol

    40. Nonaethylene Glycol Monododecyl Ether

    41. Nonaethyleneglycol Monododecyl Ether

    42. Nonaethyleneglycol Monododecyl Ethers

    43. Polidocanol

    44. Polidocanols

    45. Polyethylene Glycol 7 Lauryl Ether

    46. Polyethylene Glycol Monododecyl Ether

    47. Polyethylene Glycol-7-lauryl Ether

    48. Polyethylene Glycol-7-lauryl Ethers

    49. Polyoxyethylene 4 Dodecyl Ether

    50. Polyoxyethylene 9 Lauryl Ether

    51. Polyoxyethylene 9-lauryl Ether

    52. Polyoxyethylene 9-lauryl Ethers

    53. Polyoxyethylene Lauryl Ether

    54. Polyoxyethylene Lauryl Ethers

    55. Polyoxyethylene(4) Lauryl Ether

    56. Polyoxyethylene-4-dodecyl Ether

    57. Polyoxyethylenedodecyl Ether

    58. Polyoxyethylenedodecyl Ethers

    59. Tetraethylene Glycol Dodecyl Ether

    60. Tetraethyleneglycol Lauryl Ether

    61. Tetraethyleneglycol Lauryl Ethers

    62. Thesit

    2.3.2 Depositor-Supplied Synonyms

    1. 4536-30-5

    2. Ethylene Glycol Monododecyl Ether

    3. 2-dodecoxyethanol

    4. Ethanol, 2-(dodecyloxy)-

    5. Lauryl Ethoxylate

    6. Laureth-1

    7. Lauryl Monoethoxylate

    8. Laureth 4

    9. Aetoxisclerol

    10. Atossisclerol

    11. Ethoxysclerol

    12. Lipocol L-1

    13. Ethylene Glycol Monolauryl Ether

    14. Lauryl Alcohol Oxy Ethanol

    15. Ethoxylated Dodecyl Alcohol

    16. 2-(dodecyloxy)ethan-1-ol

    17. Dodecyl Ethyleneglycol Monoether

    18. Ethylene Glycol Mono-n-dodecyl Ether

    19. 2-hydroxyethyl Lauryl Ether

    20. Ethylene Glycol Dodecyl Ether

    21. J89tkq5r54

    22. Chebi:78770

    23. Aethoxysklerol

    24. Laureth

    25. Dsstox_cid_5218

    26. Dsstox_rid_80389

    27. Dsstox_gsid_44676

    28. Lubrol 12a9

    29. Cimagel

    30. Hydroxypolyethoxydodecane

    31. Ethanol,2-(dodecyloxy)-

    32. Slovasol S

    33. Rokanol L

    34. Romopal Ln

    35. Polyoxyethylenedodecyl Ether

    36. Lubrol Px

    37. Nikkol Bl

    38. Aldosperse L 9

    39. Actinol L3

    40. Alkasurf Lan 1

    41. Alkasurf Lan 3

    42. Carsonol L 2

    43. Carsonol L 3

    44. Chimipal Ae 3

    45. Actinol L 7

    46. Laureth-11

    47. Lauromacrogol 400

    48. Noniolite Al 20

    49. Texofor B 9

    50. 40l (polyether)

    51. Cas-4536-30-5

    52. Adeka Carpol M 2

    53. Akyporox Rlm 40

    54. Ethosperse La 12

    55. Ethosperse La 23

    56. Mergital Lm 11

    57. Polyoxyethylene 9-lauryl Ether

    58. Simulsol P 23

    59. Dodecanol, Ethoxylate

    60. Bl 9 (polyglycol)

    61. Peg-1 Lauryl Ether

    62. Pegnol L 12

    63. Akyporox Rlm 160

    64. Akyporox Rlm 230

    65. Noigen Et 160

    66. Adekatol La 1275

    67. Arapol 0712

    68. Newcol 1203

    69. Peg-11 Lauryl Ether

    70. Nonaethyleneglycol Monododecyl Ether

    71. Einecs 224-886-5

    72. Ethoxylated Lauryl Alcohol

    73. Adeka Carpol Mbf 100

    74. Brn 1748129

    75. Unii-j89tkq5r54

    76. Ai3-09524

    77. Polyoxyethylene Dodecyl Mono Ether

    78. Varithena (tn)

    79. Alpha-dodecyl-omega-hydroxypoly(oxy-1,2ethanediyl)

    80. Asclera (tn)

    81. Polidocanol (jan)

    82. Dodecyl Alcohol Polyoxyethylene Ether

    83. Mfcd00042657

    84. Brij35

    85. Laureth- 23

    86. 2-dodecyloxy-ethanol

    87. Aethoxysklerol (tn)

    88. Glycols, Polyethylene, Monododecyl Ether

    89. Laureth 4 (usan)

    90. Laureth 9 (usan)

    91. Lipocol L1

    92. Nikkol Bl 1sy

    93. Alpha-dodecyl-omega-hydroxypoly(oxyethylene)

    94. Bmse000753

    95. Brij 30 (tn)

    96. Ethoxylated Lauryl Alcohols

    97. Laureth-1 [inci]

    98. Schembl77030

    99. 4-01-00-02386 (beilstein Handbook Reference)

    100. Alpha-dodecyl-omega-hydroxypoly(oxy-1,2-ethanediyl)

    101. Polyoxyethylene 23 Lauryl Ether

    102. Chembl1201751

    103. Dtxsid8044676

    104. Poly(oxy-1,2-ethanediyl), Alpha-dodecyl-omega-hydroxy-

    105. Chebi:31765

    106. Zinc8437287

    107. Tox21_113966

    108. Tox21_301593

    109. Stl452914

    110. Akos024390811

    111. Fp-0044

    112. Ncgc00256261-01

    113. Ncgc00274074-01

    114. Monoethylene Glycol Monododecyl Ether

    115. Cs-0310513

    116. E0264

    117. Ft-0722559

    118. D01539

    119. D01993

    120. N-

    121. A-z-n-

    122. A-fmoc-l-2,4-diaminobutyric Acid

    123. T72486

    124. A902917

    125. Q377036

    126. Sr-01000944887

    127. Sr-01000944887-1

    128. Ethylene Glycol Monododecyl Ether, Bioxtra, >=99.0% (gc)

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 230.39 g/mol
    Molecular Formula C14H30O2
    XLogP35.1
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count13
    Exact Mass230.224580195 g/mol
    Monoisotopic Mass230.224580195 g/mol
    Topological Polar Surface Area29.5 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity115
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 1  
    Drug NameVarithena
    PubMed HealthPolidocanol (Injection)
    Drug ClassesSclerosing Agent
    Active IngredientPolidocanol
    Dosage FormSolution
    RouteIntravenous
    Strength180mg/18ml (10mg/ml)
    Market StatusPrescription
    CompanyProvensis

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Detergents

    Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)

    Sclerosing Solutions

    Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE. (See all compounds classified as Sclerosing Solutions.)

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