Find Tacrolimus manufacturers, exporters & distributors on PharmaCompass

Question

Looking for 104987-11-3 / Tacrolimus API manufacturers, exporters & distributors?

API | Excipient name

Tacrolimus

Synonyms

Fujimycin, 104987-11-3, Prograf, Tsukubaenolide, Protopic, Fk506

Cas Number

104987-11-3

Unique Ingredient Identifier (UNII)

Y5L2157C4J

About Tacrolimus

A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.

score 83 · Accepted Answer

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Molecular Formula	C₄₄H₆₉NO₁₂
Molecular Weight	804.0 g/mol
XLogP3	2.7
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	7
Exact Mass	803.48197664 g/mol
Monoisotopic Mass	803.48197664 g/mol
Topological Polar Surface Area	178 Å²
Heavy Atom Count	57
Formal Charge	0
Complexity	1480
Isotope Atom Count	0
Defined Atom Stereocenter Count	14
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

1 of 8
Drug Name	Astagraf xl
PubMed Health	Tacrolimus
Drug Classes	Antipsoriatic, Immune Suppressant
Drug Label	ASTAGRAF XL is available for oral administration as hard gelatin capsules (tacrolimus extended-release capsules) containing the equivalent of 0.5 mg, 1 mg or 5 mg of anhydrous tacrolimus USP. Inactive ingredients include ethylcellulose NF, hypromello...
Active Ingredient	Tacrolimus
Dosage Form	Capsule, extended release
Route	Oral
Strength	eq 5mg base; eq 0.5mg base; eq 1mg base
Market Status	Prescription
Company	Astellas

2 of 8
Drug Name	Prograf
PubMed Health	Tacrolimus
Drug Classes	Antipsoriatic, Immune Suppressant
Drug Label	Prograf is available for oral administration as capsules (tacrolimus capsules USP) containing the equivalent of 0.5 mg, 1 mg or 5 mg of anhydrous tacrolimus USP. Inactive ingredients include lactose monohydrate NF, hypromellose USP, croscarmellose so...
Active Ingredient	Tacrolimus
Dosage Form	Capsule; Injectable
Route	Injection; Oral
Strength	eq 0.5mg base; eq 5mg base; eq 1mg base; eq 5mg base/ml
Market Status	Prescription
Company	Astellas

3 of 8
Drug Name	Protopic
PubMed Health	Tacrolimus (On the skin)
Drug Classes	Antipsoriatic
Drug Label	PROTOPIC (tacrolimus) Ointment contains tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis. It is for topical dermatologic use only. Chemically, tacrolimus is designated as [3S-[3R[E(1S,3S,4S)],4S,5R,8S,9E,12R,14R...
Active Ingredient	Tacrolimus
Dosage Form	Ointment
Route	Topical
Strength	0.1%; 0.03%
Market Status	Prescription
Company	Astellas

4 of 8
Drug Name	Tacrolimus
PubMed Health	Tacrolimus
Drug Classes	Antipsoriatic, Immune Suppressant
Drug Label	Prograf is available for oral administration as capsules (tacrolimus capsules USP) containing the equivalent of 0.5 mg, 1 mg or 5 mg of anhydrous tacrolimus USP. Inactive ingredients include lactose monohydrate NF, hypromellose USP, croscarmellose so...
Active Ingredient	Tacrolimus
Dosage Form	Ointment; Capsule
Route	Oral; Topical
Strength	eq 5mg base; eq 0.5mg base; 0.1%; eq 1mg base; 0.03%
Market Status	Prescription
Company	Panacea Biotec; Accord Hlthcare; Sandoz; Strides Pharma; Fougera Pharms; Dr Reddys Labs; Mylan

Find Tacrolimus manufacturers, exporters & distributors on PharmaCompass

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CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

74 API Suppliers

31 USDMF

12 CEP/COS

8 JDMF

8 EU WC

15 KDMF

27 NDC API

33 Listed Suppliers

DEVELOPMENTS

163 Drugs in Development

INTERMEDIATES

7 Intermediate Suppliers

FINISHED DOSAGE FORMULATIONS

823 FDF Dossiers

63 FDA Orange Book

538 Europe

21 Canada

96 Australia

23 South Africa

82 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET, EXTENDED RELEASE;ORAL - EQ 0.75MG BASE

TABLET, EXTENDED RELEASE;ORAL - EQ 1MG BASE

TABLET, EXTENDED RELEASE;ORAL - EQ 4MG BASE

CAPSULE;ORAL - EQ 0.5MG BASE

CAPSULE;ORAL - EQ 1MG BASE

CAPSULE;ORAL - EQ 5MG BASE

RELATED EXCIPIENT COMPANIES

2 SPI Pharma

3 Gangwal Healthcare

6 Nanjing Well Pharmaceutical

1 Capital Farma

1 Kirsch Pharma

1 Dr. Paul Lohmann GmbH & Co. KGaA

4 ACG Worldwide

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

7 BASF

11 Corel Pharma Chem

4 DFE Pharma

1 Finar

4 Gangwal Chemicals

3 Ideal Cures

1 Ingredion Pharma Solutions

22 Kerry

1 Keval Exports

3 Kima Chemical

6 Lonza Capsugel

9 Microlex e.U

1 Nanjing Bold Chemical

1 Neelkanth MineChem

1 Nitika Pharmaceutical Specialities

1 Novo Excipients

4 Pluviaendo

2 Prachin Pharmachem

1 Qianhao Chemical (Hebei) Co., Ltd

2 Qualicaps

3 Roquette

7 Seppic

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

3 Sigachi Industries

2 Silverline Chemicals

2 The Dow Chemical Company

1 Valens Pharmachem

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

39 Coating Systems & Additives

19 Fillers, Diluents & Binders

18 Granulation

17 Direct Compression

13 Lubricants & Glidants

12 Controlled & Modified Release

11 Film Formers & Plasticizers

9 Empty Capsules

9 Disintegrants & Superdisintegrants

8 Solubilizers