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Chemistry

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Also known as:
Molecular Formula
C20H28N12O9PPt+
Molecular Weight
806.6  g/mol
InChI Key
BWNPJEJDQASSEO-UHFFFAOYSA-M

Cisplatin
1 2D Structure

Cisplatin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] phosphate;azanide;platinum(4+)
2.1.2 InChI
InChI=1S/C20H25N10O9P.2H2N.Pt/c21-16-14-17(24-5-23-16)29(6-25-14)13-2-9(10(3-31)37-13)39-40(34,35)36-4-11-8(32)1-12(38-11)30-7-26-15-18(30)27-20(22)28-19(15)33;;;/h5-13,31-32H,1-4H2,(H,34,35)(H2,21,23,24)(H3,22,27,28,33);2*1H2;/q;2*-1;+4/p-1
2.1.3 InChI Key
BWNPJEJDQASSEO-UHFFFAOYSA-M
2.1.4 Canonical SMILES
C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)([O-])OC4CC(OC4CO)N5C=NC6=C(N=CN=C65)N)O.[NH2-].[NH2-].[Pt+4]
2.1.5 Isomeric SMILES
C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)([O-])OC4CC(OC4CO)N5C=NC6=C(N=CN=C65)N)O.[NH2-].[NH2-].[Pt+4]
2.2 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 806.6 g/mol
Molecular Formula C20H28N12O9PPt+
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count16
Rotatable Bond Count1
Exact Mass806.148777 g/mol
Monoisotopic Mass806.148777 g/mol
Topological Polar Surface Area274 A^2
Heavy Atom Count43
Formal Charge1
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count6
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count4

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SOLA BRIDGE,,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1695234600,"product":"CISPLATIN","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FLAVINE NORH AMERICA INC","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN","customer":"GLAND PHARMA LIMITEDUNIT 2","customerCountry":"INDIA","quantity":"9.24","actualQuantity":"9235","unit":"GMS","unitRateFc":"31.5","totalValueFC":"294203","currency":"USD","unitRateINR":"2644.4","date":"21-Sep-2023","totalValueINR":"24421265","totalValueInUsd":"294203","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29339990","bill_no":"1001760","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN","supplierAddress":"N\/A","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1697740200,"product":"CISPLATIN","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FLAVIANE NORTH AMERICA INC","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN","customer":"GLAND PHARMA LIMITEDUNIT 2","customerCountry":"INDIA","quantity":"2.32","actualQuantity":"2315","unit":"GMS","unitRateFc":"31.9","totalValueFC":"74709.8","currency":"USD","unitRateINR":"2686","date":"20-Oct-2023","totalValueINR":"6218044","totalValueInUsd":"74709.8","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29339990","bill_no":"1001943","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN","supplierAddress":"N\/A","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699900200,"product":"CISPLATIN","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FLAVINE NORTH AMERICAINC","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN","customer":"GLAND PHARMA LIMITEDUNIT 2","customerCountry":"INDIA","quantity":"2.37","actualQuantity":"2370","unit":"GMS","unitRateFc":"30.9","totalValueFC":"74006.1","currency":"USD","unitRateINR":"2600.2","date":"14-Nov-2023","totalValueINR":"6162557","totalValueInUsd":"74006.1","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29339990","bill_no":"1002090","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN","supplierAddress":"10 REUTEN DRIVE CLOSTER NJ 07624 UNITED STATES","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718130600,"product":"CHEMICAL : CISPLATIN","address":"10\/13, NR. 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SOLA BRIDGE,,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727893800,"product":"CISPLATIN EP","address":"2ND FLOOR, CHINUBHAI CENTRE,,OFF.","city":"AHMEDABAD,GUJARAT","supplier":"FLAVINE NORTH AMERICA INC","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN","customer":"INTAS PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"23.00","actualQuantity":"23000","unit":"GMS","unitRateFc":"29","totalValueFC":"671552","currency":"USD","unitRateINR":"2453.4","date":"03-Oct-2024","totalValueINR":"56428200","totalValueInUsd":"671552","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29420090","bill_no":"5930224","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN","supplierAddress":"61 South Paramus Road, Suite 565 Paramus, New Jersey 07652 USA SDNF UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,,OFF."},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1736533800,"product":"CISPLATIN, CAS NO-15663-27-1,BATCH NO-434240020,433240020 CISPLATIN, CAS NO-15663-27-1","address":"B-310, SOM DATT CHAMBERS, 1,","city":"NEW DELHI","supplier":"FLAVIN NORTH AMERICA INC","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"FRESENIUS KABI ONCOLOGY LIMITED","customerCountry":"INDIA","quantity":"4.55","actualQuantity":"4550","unit":"GMS","unitRateFc":"33.6","totalValueFC":"153674.5","currency":"USD","unitRateINR":"2912.4","date":"11-Jan-2025","totalValueINR":"13251228.9","totalValueInUsd":"153674.5","indian_port":"Delhi Air","hs_no":"29146990","bill_no":"7744484","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"61,SOUTH PARAMUS ROAD,SUITE 565,PAR AMUS NEW JERSEY 07652 U.S.A. SDNF UNITED STATES","customerAddress":"B-310, SOM DATT CHAMBERS, 1,"}]
22-Jan-2022
04-Feb-2025
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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - 0.5MG/ML

USFDA APPLICATION NUMBER - 18057

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DOSAGE - INJECTABLE;INJECTION - 10MG/VIAL

USFDA APPLICATION NUMBER - 18057

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DOSAGE - INJECTABLE;INJECTION - 1MG/ML

USFDA APPLICATION NUMBER - 18057

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DOSAGE - INJECTABLE;INJECTION - 50MG/VIAL

USFDA APPLICATION NUMBER - 18057

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ABOUT THIS PAGE

Looking for / Cisplatin API manufacturers, exporters & distributors?

Cisplatin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cisplatin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cisplatin manufacturer or Cisplatin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cisplatin manufacturer or Cisplatin supplier.

PharmaCompass also assists you with knowing the Cisplatin API Price utilized in the formulation of products. Cisplatin API Price is not always fixed or binding as the Cisplatin Price is obtained through a variety of data sources. The Cisplatin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cisplatin

PLATINOL Manufacturers

A PLATINOL manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of PLATINOL, including repackagers and relabelers. The FDA regulates PLATINOL manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. PLATINOL API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of PLATINOL manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

PLATINOL Suppliers

A PLATINOL supplier is an individual or a company that provides PLATINOL active pharmaceutical ingredient (API) or PLATINOL finished formulations upon request. The PLATINOL suppliers may include PLATINOL API manufacturers, exporters, distributors and traders.

click here to find a list of PLATINOL suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

PLATINOL USDMF

A PLATINOL DMF (Drug Master File) is a document detailing the whole manufacturing process of PLATINOL active pharmaceutical ingredient (API) in detail. Different forms of PLATINOL DMFs exist exist since differing nations have different regulations, such as PLATINOL USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A PLATINOL DMF submitted to regulatory agencies in the US is known as a USDMF. PLATINOL USDMF includes data on PLATINOL's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The PLATINOL USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of PLATINOL suppliers with USDMF on PharmaCompass.

PLATINOL JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The PLATINOL Drug Master File in Japan (PLATINOL JDMF) empowers PLATINOL API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the PLATINOL JDMF during the approval evaluation for pharmaceutical products. At the time of PLATINOL JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of PLATINOL suppliers with JDMF on PharmaCompass.

PLATINOL KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a PLATINOL Drug Master File in Korea (PLATINOL KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of PLATINOL. The MFDS reviews the PLATINOL KDMF as part of the drug registration process and uses the information provided in the PLATINOL KDMF to evaluate the safety and efficacy of the drug.

After submitting a PLATINOL KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their PLATINOL API can apply through the Korea Drug Master File (KDMF).

click here to find a list of PLATINOL suppliers with KDMF on PharmaCompass.

PLATINOL CEP

A PLATINOL CEP of the European Pharmacopoeia monograph is often referred to as a PLATINOL Certificate of Suitability (COS). The purpose of a PLATINOL CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of PLATINOL EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of PLATINOL to their clients by showing that a PLATINOL CEP has been issued for it. The manufacturer submits a PLATINOL CEP (COS) as part of the market authorization procedure, and it takes on the role of a PLATINOL CEP holder for the record. Additionally, the data presented in the PLATINOL CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the PLATINOL DMF.

A PLATINOL CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. PLATINOL CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of PLATINOL suppliers with CEP (COS) on PharmaCompass.

PLATINOL WC

A PLATINOL written confirmation (PLATINOL WC) is an official document issued by a regulatory agency to a PLATINOL manufacturer, verifying that the manufacturing facility of a PLATINOL active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting PLATINOL APIs or PLATINOL finished pharmaceutical products to another nation, regulatory agencies frequently require a PLATINOL WC (written confirmation) as part of the regulatory process.

click here to find a list of PLATINOL suppliers with Written Confirmation (WC) on PharmaCompass.

PLATINOL NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing PLATINOL as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for PLATINOL API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture PLATINOL as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain PLATINOL and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a PLATINOL NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of PLATINOL suppliers with NDC on PharmaCompass.

PLATINOL GMP

PLATINOL Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of PLATINOL GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right PLATINOL GMP manufacturer or PLATINOL GMP API supplier for your needs.

PLATINOL CoA

A PLATINOL CoA (Certificate of Analysis) is a formal document that attests to PLATINOL's compliance with PLATINOL specifications and serves as a tool for batch-level quality control.

PLATINOL CoA mostly includes findings from lab analyses of a specific batch. For each PLATINOL CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

PLATINOL may be tested according to a variety of international standards, such as European Pharmacopoeia (PLATINOL EP), PLATINOL JP (Japanese Pharmacopeia) and the US Pharmacopoeia (PLATINOL USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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