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Chemistry

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Also known as: 123663-49-0, N-(7-(methylsulfonamido)-4-oxo-6-phenoxy-4h-chromen-3-yl)formamide, Careram, Kolbet, T-614, Iguratimod [inn]
Molecular Formula
C17H14N2O6S
Molecular Weight
374.4  g/mol
InChI Key
ANMATWQYLIFGOK-UHFFFAOYSA-N
FDA UNII
4IHY34Y2NV

Iguratimod
Iguratimod is under investigation in Rheumatoid Arthritis.
1 2D Structure

Iguratimod

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[7-(methanesulfonamido)-4-oxo-6-phenoxychromen-3-yl]formamide
2.1.2 InChI
InChI=1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20)
2.1.3 InChI Key
ANMATWQYLIFGOK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CS(=O)(=O)NC1=C(C=C2C(=C1)OC=C(C2=O)NC=O)OC3=CC=CC=C3
2.2 Other Identifiers
2.2.1 UNII
4IHY34Y2NV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-formylamino-7-methylsulfonylamino-6-phenoxy-4h-1-benzopyran-4-one

2. T 614

3. T-614

2.3.2 Depositor-Supplied Synonyms

1. 123663-49-0

2. N-(7-(methylsulfonamido)-4-oxo-6-phenoxy-4h-chromen-3-yl)formamide

3. Careram

4. Kolbet

5. T-614

6. Iguratimod [inn]

7. Iremod

8. 4ihy34y2nv

9. 3-formylamino-7-methylsulfonylamino-6-phenoxy-4h-1-benzopyran-4-one

10. Ncgc00181783-02

11. T614

12. N-[7-(methanesulfonamido)-4-oxo-6-phenoxychromen-3-yl]formamide

13. N-[7-methanesulfonamido-4-oxo-6-(phenoxy)chromen-3-yl]formamide

14. N-(7-((methylsulfonyl)amino)-4-oxo-6-phenoxy-4h-1-benzopyran-3-yl)formamide

15. Unii-4ihy34y2nv

16. Colvet

17. T 614

18. Iguratimod- Bio-x

19. Iguratimod [mi]

20. Iguratimod (jan/inn)

21. Iguratimod [jan]

22. Dsstox_cid_28897

23. Dsstox_rid_83165

24. Iguratimod [who-dd]

25. Dsstox_gsid_48971

26. Schembl26326

27. Gtpl9736

28. Chembl2107455

29. Dtxsid0048971

30. Iguratimod, >=98% (hplc)

31. Chebi:31689

32. Bcp04206

33. Tox21_113422

34. Bdbm50458537

35. Mfcd00882374

36. S5648

37. Akos015888743

38. Zinc100018451

39. Ccg-268349

40. Cs-0617

41. Db12233

42. Sb16814

43. Ncgc00181783-01

44. Ncgc00181783-03

45. As-12959

46. Bi164569

47. Hy-17009

48. A3484

49. Cas-123663-49-0

50. Ft-0654508

51. I0945

52. C71931

53. D01146

54. 663i490

55. A805134

56. Sr-01000945251

57. J-521483

58. Sr-01000945251-1

59. Q13575264

60. N-(3-formamido-4-oxo-6-phenoxy-4h-chromen-7-yl)methanesulfonamide

61. N-[7-(methanesulfonamido)-4-oxo-6-phenoxy-4h-chromen-3-yl]formamide

62. N-[7-(methanesulfonamido)-4-oxo-6-phenoxy-chromen-3-yl]formamide;iguratimod

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 374.4 g/mol
Molecular Formula C17H14N2O6S
XLogP31.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass374.05725734 g/mol
Monoisotopic Mass374.05725734 g/mol
Topological Polar Surface Area119 Ų
Heavy Atom Count26
Formal Charge0
Complexity665
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

Listed Suppliers

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01

Minakem

France
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  • EDQM
  • WHO-GMP

Virtual BoothMinakem delivers API, HPAPI, steroids & CDMO services for generics with FDA/GMP certification, regulatory know-how & proven success.

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Iguratimod

About the Company : MINAKEM is a cGMP custom manufacturer of small molecule API, HPAPI and steroids. All development and manufacturing activities are supported by highly skilled R&D teams, supported b...

MINAKEM is a cGMP custom manufacturer of small molecule API, HPAPI and steroids. All development and manufacturing activities are supported by highly skilled R&D teams, supported by strong analytical and regulatory affairs services. The R&D team has an expertise in process development, organic synthesis, and works under a secrecy agreement to protect your IP. With 3 production sites in Europe and 1 in Canada, Minakem is ready to support your strategic sourcing projects or your reshoring activities. Recently launched commercial generic API: Apixaban, Mirabegron, Fulvestrant, remifentanil, esmolol,
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02

  • fda
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  • WHO-GMP

Virtual BoothZhejiang Hengkang Pharm Group is a dynamic pharmaceutical entity, spanning drug research, large-scale production, and global marketing.

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Iguratimod

About the Company : Established in 2004 and headquartered in Hangzhou, Hengkang established multiple factories, research and sales centers in Zhejiang, Shandong, and Henan. With facilities conforming ...

Established in 2004 and headquartered in Hangzhou, Hengkang established multiple factories, research and sales centers in Zhejiang, Shandong, and Henan. With facilities conforming to global API standards, along with professional R&D and marketing teams, Hengkang’s operations span major pharmaceutical markets such as China, Europe, the CIS region, Japan, and South Korea. Hengkang has established long-term and stable relationships with nearly 70 countries overseas and hundreds of domestic enterprises.
Zhejiang Hengkang Pharmaceutical

03

Allastir

India
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Allastir

India
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Iguratimod

About the Company : Allastir instituted the services in 2010 with a motive to cater the pharmaceutical industry with niche API's. In Allastir we strongly believe in team work and customer satisfaction...

Allastir instituted the services in 2010 with a motive to cater the pharmaceutical industry with niche API's. In Allastir we strongly believe in team work and customer satisfaction. Allastir is backed by the strong R&D team who are passionate about what they do. We manufacture niche API's with high quality which are suitable for formulations like tablets, capsules, soft gelatins and oral liquids.To be the larder to develop innovative niche molecule to the health care industry for the betterment of human life.Our Vision is to be the Number ONE company in Health care Industry in the World.
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04

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Iguratimod

About the Company : Anhui Biochem Pharmaceutical Co., Ltd. is a high tech enterprise which has integrated R&D, production and marketing specializing in synthetic technology of chiral compounds. We has...

Anhui Biochem Pharmaceutical Co., Ltd. is a high tech enterprise which has integrated R&D, production and marketing specializing in synthetic technology of chiral compounds. We has complete industry chain from API to FPPs products. We also have the largest, most complete line of anti-AIDS&HBV API Production facilities. The API products include Lamivudine USP, Zidovudine USP, Ritonavir USP, lopinavir, Nevirapine USP, Tenofovir Disoproxil Fumarate, Entecavir, NGF(Mouse Nerve Growth Factor), Capecitabine and other intermediates. The FPPs products include Lamivudine Tablet(100mg/150mg/300mg)
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Iguratimod

About the Company : Calidrux Lifesciences LLP, established in 2023 in Gujarat, is a leading wholesaler of Active Pharmaceutical Ingredients (APIs), acid dyes, and more. Committed to quality and reliab...

Calidrux Lifesciences LLP, established in 2023 in Gujarat, is a leading wholesaler of Active Pharmaceutical Ingredients (APIs), acid dyes, and more. Committed to quality and reliability, we provide high-grade products to meet the diverse needs of the pharmaceutical and chemical industries. With a focus on excellence and customer satisfaction, we strive to deliver superior solutions that contribute to the growth and success of our clients, while ensuring compliance with industry standards.
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Iguratimod

About the Company : Guangzhou Topwork Chemical Co., Ltd. Specializes in manufacturing corticosteroid and relative intermediates. We provide high quality products and excellent service to our clients a...

Guangzhou Topwork Chemical Co., Ltd. Specializes in manufacturing corticosteroid and relative intermediates. We provide high quality products and excellent service to our clients and have gained a high business reputation in the world market. Topwork gathers a group of energetic, hardworking and much experienced experts. They dedicate their entire efforts to research and development of new products. To guarantee the quality of our products, we have established an international standard quality control system. All of our products conform the latest standard of USP, EP, BP and CP.
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Lewens Labs

India
IFT FIRST
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Lewens Labs

India
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Iguratimod

About the Company : Lewens Labs finds its roots in 4 years of engineering during which we saw a dream to carve out a niche for ourselves in Pharmaceutical Industry. As a part of the final year project...

Lewens Labs finds its roots in 4 years of engineering during which we saw a dream to carve out a niche for ourselves in Pharmaceutical Industry. As a part of the final year project, We worked on cost reduction of “Aceclofenac” which fetched us four national awards including one from Consultancy Development Center, Government of India. At Lewens, We aim to develop and provide quality,cost effective and sustainable solutions to our Customers by empowering people to think beyond the traditional norms of Chemistry and Engineering to come up with different and innovative solutions to the problems.
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Maiden Group

India
IFT FIRST
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Maiden Group

India
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Iguratimod

About the Company : We are Maiden, a rapidly growing Indian pharma company committed to developing, manufacturing and marketing diverse portfolio of products. Our core strength lies in development, up...

We are Maiden, a rapidly growing Indian pharma company committed to developing, manufacturing and marketing diverse portfolio of products. Our core strength lies in development, up scaling and manufacturing differentiated formulations. Various national and multi-national pharmaceutical companies across geographies rely on our expertises to deliver world class quality products. Maiden complies with various National / International regulatory norms and standards. We strive hard to make a difference in people lives, through our innovative healthcare solutions.
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09

IFT FIRST
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Iguratimod

About the Company : Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry since our inception in 1988. Our resources are dedicated to promoting better health ...

Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry since our inception in 1988. Our resources are dedicated to promoting better health through products that offer superior value. Located in Pithampur, Madhya Pradesh, Medilux Laboratories is committed to strategic research, delivering a complex range of globally benchmarked chemistries. Our products and services are rapidly making strides in the global pharmaceutical space, giving us the impetus to constantly strive for excellence and provide quality customer service.
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10

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Iguratimod

About the Company : Established in 1999, Hankang Pharmaceutical Group stands as a prominent CRO-CDMO integrated service enterprise in China. Focused on generic drugs while venturing into innovative on...

Established in 1999, Hankang Pharmaceutical Group stands as a prominent CRO-CDMO integrated service enterprise in China. Focused on generic drugs while venturing into innovative ones, the group is dedicated to offering comprehensive solutions to the industry. Presently, Hankang has crafted over 200 varieties for 600+ domestic and international companies, serving 10+ innovative drugs. It has successfully developed more than 10 initial generic drugs, with over 20 varieties endorsed by the top three domestic companies and 30 exceeding a 100 million output value.
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API Reference Price

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10-Jul-2023
28-Oct-2024
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INTERMEDIATE SUPPLIERS

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01

IFT FIRST
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CAS Number : 149436-41-9

End Use API : Iguratimod

About The Company : Hiray Pharma Solutions is an international end-to-end CDMO, facilitating the development and manufacturing of important drug products and key intermediates arou...

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Iguratimod manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Iguratimod API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Iguratimod manufacturer or Iguratimod supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Iguratimod manufacturer or Iguratimod supplier.

PharmaCompass also assists you with knowing the Iguratimod API Price utilized in the formulation of products. Iguratimod API Price is not always fixed or binding as the Iguratimod Price is obtained through a variety of data sources. The Iguratimod Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Iguratimod

Synonyms

123663-49-0, N-(7-(methylsulfonamido)-4-oxo-6-phenoxy-4h-chromen-3-yl)formamide, Careram, Kolbet, T-614, Iguratimod [inn]

Cas Number

123663-49-0

Unique Ingredient Identifier (UNII)

4IHY34Y2NV

About Iguratimod

Iguratimod is under investigation in Rheumatoid Arthritis.

Iguratimod Manufacturers

A Iguratimod manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Iguratimod, including repackagers and relabelers. The FDA regulates Iguratimod manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Iguratimod API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Iguratimod manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Iguratimod Suppliers

A Iguratimod supplier is an individual or a company that provides Iguratimod active pharmaceutical ingredient (API) or Iguratimod finished formulations upon request. The Iguratimod suppliers may include Iguratimod API manufacturers, exporters, distributors and traders.

click here to find a list of Iguratimod suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Iguratimod USDMF

A Iguratimod DMF (Drug Master File) is a document detailing the whole manufacturing process of Iguratimod active pharmaceutical ingredient (API) in detail. Different forms of Iguratimod DMFs exist exist since differing nations have different regulations, such as Iguratimod USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Iguratimod DMF submitted to regulatory agencies in the US is known as a USDMF. Iguratimod USDMF includes data on Iguratimod's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Iguratimod USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Iguratimod suppliers with USDMF on PharmaCompass.

Iguratimod JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Iguratimod Drug Master File in Japan (Iguratimod JDMF) empowers Iguratimod API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Iguratimod JDMF during the approval evaluation for pharmaceutical products. At the time of Iguratimod JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Iguratimod suppliers with JDMF on PharmaCompass.

Iguratimod GMP

Iguratimod Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Iguratimod GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Iguratimod GMP manufacturer or Iguratimod GMP API supplier for your needs.

Iguratimod CoA

A Iguratimod CoA (Certificate of Analysis) is a formal document that attests to Iguratimod's compliance with Iguratimod specifications and serves as a tool for batch-level quality control.

Iguratimod CoA mostly includes findings from lab analyses of a specific batch. For each Iguratimod CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Iguratimod may be tested according to a variety of international standards, such as European Pharmacopoeia (Iguratimod EP), Iguratimod JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Iguratimod USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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