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    Chemistry

    Click the arrow to open the dropdown
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    Also known as: 49562-28-9, Procetofen, Lipantil, Tricor, Lipanthyl, Antara
    Molecular Formula
    C20H21ClO4
    Molecular Weight
    360.8  g/mol
    InChI Key
    YMTINGFKWWXKFG-UHFFFAOYSA-N
    FDA UNII
    U202363UOS
    Fenofibrate
    An antilipemic agent which reduces both CHOLESTEROL and TRIGLYCERIDES in the blood.
    Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist. The mechanism of action of fenofibrate is as a Peroxisome Proliferator-activated Receptor alpha Agonist.
    1 2D Structure

    Fenofibrate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
    2.1.2 InChI
    InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
    2.1.3 InChI Key
    YMTINGFKWWXKFG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    U202363UOS
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Antara Micronized Procetofen

    2. Apo Feno Micro

    3. Apo Fenofibrate

    4. Apo-feno-micro

    5. Apo-fenofibrate

    6. Azu, Fenofibrat

    7. Cil

    8. Controlip

    9. Debat, Fnofibrate

    10. Durafenat

    11. Fnofibrate Debat

    12. Fnofibrate Msd

    13. Fenobeta

    14. Fenofanton

    15. Fenofibrat Abz

    16. Fenofibrat Al

    17. Fenofibrat Azu

    18. Fenofibrat Fph

    19. Fenofibrat Heumann

    20. Fenofibrat Hexal

    21. Fenofibrat Ratiopharm

    22. Fenofibrat Stada

    23. Fenofibrat Von Ct

    24. Fenofibrat-ratiopharm

    25. Gen Fenofibrate

    26. Gen-fenofibrate

    27. Heumann, Fenofibrat

    28. Hexal, Fenofibrat

    29. Lf 178

    30. Lf-178

    31. Lf178

    32. Lipanthyl

    33. Lipantil

    34. Liparison

    35. Lipidil

    36. Lipidil Ter

    37. Lipidil-ter

    38. Livesan

    39. Lofibra

    40. Micronized Procetofen, Antara

    41. Mtw Fenofibrat

    42. Mtw-fenofibrat

    43. Normalip

    44. Novo Fenofibrate

    45. Novo-fenofibrate

    46. Nu Fenofibrate

    47. Nu-fenofibrate

    48. Phenofibrate

    49. Pms Fenofibrate Micro

    50. Pms-fenofibrate Micro

    51. Procetofen

    52. Procetofen, Antara Micronized

    53. Procetofene

    54. Secalip

    55. Stada, Fenofibrat

    56. Supralip

    57. Tricor

    2.3.2 Depositor-Supplied Synonyms

    1. 49562-28-9

    2. Procetofen

    3. Lipantil

    4. Tricor

    5. Lipanthyl

    6. Antara

    7. Lipidil

    8. Fenobrate

    9. Secalip

    10. Triglide

    11. Fenoglide

    12. Finofibrate

    13. Lipoclar

    14. Lipofene

    15. Proctofene

    16. Fenogal

    17. Lipirex

    18. Lipofen

    19. Sedufen

    20. Elasterin

    21. Fenotard

    22. Protolipan

    23. Ankebin

    24. Lipidex

    25. Lipifen

    26. Liposit

    27. Lipsin

    28. Nolipax

    29. Fenofibratum [inn-latin]

    30. Propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

    31. Fenofibrato [inn-spanish]

    32. Lipantil (tn)

    33. Tricor (tn)

    34. Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

    35. Lf-178

    36. Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate

    37. 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic Acid 1-methylethyl Ester

    38. Nsc 281319

    39. Fenofibrate Micronized

    40. Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate

    41. Fnf

    42. Propanoic Acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl Ester

    43. Elasterate

    44. Procetofene

    45. Luxacor

    46. Mfcd00133314

    47. Fenofibrate Delayed Release

    48. Chembl672

    49. Mls000028515

    50. Chebi:5001

    51. Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate

    52. Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

    53. Lofibra

    54. U202363uos

    55. Propanoic Acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl Ester

    56. Nsc-281319

    57. Ncgc00015437-10

    58. Fenofibrato

    59. Fenofibratum

    60. Smr000058299

    61. Supralip

    62. Cas-49562-28-9

    63. Dsstox_cid_9874

    64. Propan-2-yl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate

    65. Dsstox_rid_78828

    66. Dsstox_gsid_29874

    67. Tricor (micronized)

    68. Antara (micronized)

    69. Fenomax

    70. Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate

    71. Pharmavit

    72. Fenofibrate (micronized)

    73. Fulcro

    74. Cip-fenofibrate

    75. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic Acid 1-methylethyl Ester

    76. Lcp-fenochol

    77. Lcp-feno

    78. Triglide (tn)

    79. Fenofibrate Idd-p

    80. Lipofen (tn)

    81. Antara (tn)

    82. Ccris 7282

    83. Sr-01000000091

    84. Einecs 256-376-3

    85. Lf 178

    86. Brn 2062462

    87. Procetoken

    88. Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionate

    89. Unii-u202363uos

    90. Hsdb 7736

    91. Fenofibrate,(s)

    92. Grs-027

    93. Fenofibrate [usan:usp:inn:ban]

    94. Prestwick_217

    95. Spectrum_001250

    96. Opera_id_328

    97. Fenofibrate [mi]

    98. Prestwick0_000275

    99. Prestwick1_000275

    100. Prestwick2_000275

    101. Prestwick3_000275

    102. Spectrum2_001390

    103. Spectrum3_001431

    104. Spectrum4_000413

    105. Spectrum5_001479

    106. Fenofibrate [inn]

    107. Fenofibrate [jan]

    108. Lopac-f-6020

    109. Fenofibrate [hsdb]

    110. Fenofibrate [usan]

    111. Ec 256-376-3

    112. F 6020

    113. Fenofibrate [vandf]

    114. Schembl4670

    115. Fenofibrate [mart.]

    116. Lopac0_000486

    117. Bspbio_000150

    118. Bspbio_003162

    119. Fenofibrate [usp-rs]

    120. Fenofibrate [who-dd]

    121. Kbiogr_000706

    122. Kbioss_001730

    123. Mls001148191

    124. Mls002548878

    125. Bidd:gt0574

    126. Divk1c_000557

    127. Fenofibrate (jan/usp/inn)

    128. Spectrum1501010

    129. Spbio_001380

    130. Spbio_002369

    131. Fenofibrate [ema Epar]

    132. Fenofibrate, >=99%, Powder

    133. Bpbio1_000166

    134. Fenofibrate (tricor, Trilipix)

    135. Gtpl7186

    136. Dtxsid2029874

    137. Hms501l19

    138. Kbio1_000557

    139. Kbio2_001730

    140. Kbio2_004298

    141. Kbio2_006866

    142. Kbio3_002382

    143. Fenofibrate [orange Book]

    144. Ninds_000557

    145. Fenofibrate [ep Monograph]

    146. Fenofibrate [usp Impurity]

    147. Hms1568h12

    148. Hms1921b17

    149. Hms2090g20

    150. Hms2092b05

    151. Hms2095h12

    152. Hms2231b14

    153. Hms3259k03

    154. Hms3261b13

    155. Hms3369m13

    156. Hms3649d20

    157. Hms3655k12

    158. Hms3712h12

    159. Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate

    160. Pharmakon1600-01501010

    161. Zinc584092

    162. Fenofibrate [usp Monograph]

    163. Albb-028958

    164. Bcp21243

    165. Tox21_110147

    166. Tox21_300151

    167. Tox21_500486

    168. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic Acid Isopropyl Ester

    169. Bdbm50085042

    170. Ccg-38996

    171. Nsc281319

    172. Nsc757822

    173. S1794

    174. Akos005107777

    175. Tox21_110147_1

    176. Ab03716

    177. Ac-4227

    178. Cs-0892

    179. Db01039

    180. Lp00486

    181. Ms-2223

    182. Nc00452

    183. Nsc-757822

    184. Sdccgsbi-0050470.p004

    185. Idi1_000557

    186. Ncgc00015437-01

    187. Ncgc00015437-02

    188. Ncgc00015437-03

    189. Ncgc00015437-04

    190. Ncgc00015437-05

    191. Ncgc00015437-06

    192. Ncgc00015437-07

    193. Ncgc00015437-08

    194. Ncgc00015437-09

    195. Ncgc00015437-11

    196. Ncgc00015437-12

    197. Ncgc00015437-13

    198. Ncgc00015437-14

    199. Ncgc00015437-16

    200. Ncgc00015437-17

    201. Ncgc00015437-31

    202. Ncgc00021475-03

    203. Ncgc00021475-04

    204. Ncgc00021475-05

    205. Ncgc00021475-06

    206. Ncgc00021475-07

    207. Ncgc00021475-08

    208. Ncgc00253945-01

    209. Ncgc00261171-01

    210. Fenofibrate (micronized) (fenofibrate

    211. Fenofibrate, Analytical Reference Material

    212. Hy-17356

    213. Sy052561

    214. Sbi-0050470.p003

    215. Db-051642

    216. Ab00052196

    217. Eu-0100486

    218. F0674

    219. Ft-0626400

    220. Ft-0654669

    221. Sw196525-4

    222. C07586

    223. D00565

    224. Ab00052196-15

    225. Ab00052196-16

    226. Ab00052196_17

    227. Ab00052196_18

    228. 562f289

    229. A827746

    230. Q419724

    231. Q-201111

    232. Sr-01000000091-2

    233. Sr-01000000091-5

    234. Sr-01000000091-6

    235. Sr-01000000091-8

    236. Brd-k50388907-001-05-6

    237. Brd-k50388907-001-18-9

    238. Brd-k50388907-001-20-5

    239. Sr-01000000091-16

    240. Z2768724415

    241. Fenofibrate, European Pharmacopoeia (ep) Reference Standard

    242. Isopropyl 2-(4-(4-chlorobenzoyl)-phenoxy)-2-methylpropanoate

    243. 1-methylethyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

    244. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoicacidisopropylester

    245. Fenofibrate, United States Pharmacopeia (usp) Reference Standard

    246. Isopropyl (4''-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate

    247. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic Acid 1-methyl-ethyl Ester

    248. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester

    249. Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material

    250. Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate;fenofibrate

    251. Propanoic Acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethylester

    2.3.3 Other Synonyms

    1. 42017-89-0

    2. Fenofibric Acid

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 360.8 g/mol
    Molecular Formula C20H21ClO4
    XLogP35.2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count7
    Exact Mass360.1128368 g/mol
    Monoisotopic Mass360.1128368 g/mol
    Topological Polar Surface Area52.6 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity458
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 16  
    Drug NameAntara
    PubMed HealthFenofibrate (By mouth)
    Drug ClassesAntihyperlipidemic
    Drug LabelFenofibrate, is a lipid regulating agent available as tablets for oral administration. Each tablet contains 54 mg or 160 mg of fenofibrate, USP. The chemical name for fenofibrate is 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid, 1-methylethy...
    Active IngredientFenofibrate
    Dosage FormCapsule
    RouteOral
    Strength43mg; 130mg; 30mg; 90mg
    Market StatusPrescription
    CompanyLupin Atlantis

    2 of 16  
    Drug NameFenofibrate
    PubMed HealthFenofibrate (By mouth)
    Drug ClassesAntihyperlipidemic
    Active IngredientFenofibrate
    Dosage FormCapsule
    RouteOral
    Strength43mg; 200mg; 130mg; 67mg; 134mg
    Market StatusPrescription
    CompanyMylan Pharms; Teva; Apotex; Dr Reddys Labs Sa; Impax Labs

    3 of 16  
    Drug NameFenofibrate
    PubMed HealthFenofibric acid (By mouth)
    Drug ClassesAntihyperlipidemic
    Drug LabelFENOGLIDE (fenofibrate) Tablets, is a lipid regulating agent available as tablets for oral administration. Each tablet contains 40 mg or 120 mg fenofibrate. The chemical name for fenofibrate is 2-[4-(4-chlorobenzoyl) phenoxy]-2-methyl-propanoic acid,...
    Active IngredientFenofibrate
    Dosage FormTablet; Capsule
    Routeoral; Oral
    Strength43mg; 160mg; 54mg; 48mg; 130mg; 107mg; 145mg
    Market StatusTentative Approval; Prescription
    CompanyMylan Pharms; Ranbaxy; Valeant Intl; Teva; Lupin; Mylan; Impax Labs

    4 of 16  
    Drug NameFenoglide
    Drug LabelLIPOFEN (fenofibrate capsules, USP), is a lipid regulating agent available as hard gelatin capsules for oral administration. Each hard gelatin capsule contains 50 or 150 mg of fenofibrate, USP. The chemical name for fenofibrate is 2-[4-(4-chloroben...
    Active IngredientFenofibrate
    Dosage FormTablet
    RouteOral
    Strength120mg; 40mg
    Market StatusPrescription
    CompanySantarus

    5 of 16  
    Drug NameFibricor
    Drug LabelTRICOR (fenofibrate tablets), is a lipid regulating agent available as tablets for oral administration. Each tablet contains 48 mg or 145 mg of fenofibrate. The chemical name for fenofibrate is 2-[4-(4-chlorobenzoyl) phenoxy]-2-methyl-propanoic acid,...
    Active IngredientFenofibric acid
    Dosage FormTablet
    RouteOral