Find Clorexolone manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Chlorexolone, 2127-01-7, Clorexolon, Flonatril, Nefrolan, Klorex
Molecular Formula
C14H17ClN2O3S
Molecular Weight
328.8  g/mol
InChI Key
VPMWFZKOWULPGT-UHFFFAOYSA-N
FDA UNII
Q2PLT3FS05

Clorexolone
Clorexolone is a sulfonamide-based diuretic with thiazide-like activity. Cloreloxone has actions similar to that of thiazide diuretics.
1 2D Structure

Clorexolone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide
2.1.2 InChI
InChI=1S/C14H17ClN2O3S/c15-12-6-9-8-17(10-4-2-1-3-5-10)14(18)11(9)7-13(12)21(16,19)20/h6-7,10H,1-5,8H2,(H2,16,19,20)
2.1.3 InChI Key
VPMWFZKOWULPGT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CCC(CC1)N2CC3=CC(=C(C=C3C2=O)S(=O)(=O)N)Cl
2.2 Other Identifiers
2.2.1 UNII
Q2PLT3FS05
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Chlorexolone

2.3.2 Depositor-Supplied Synonyms

1. Chlorexolone

2. 2127-01-7

3. Clorexolon

4. Flonatril

5. Nefrolan

6. Klorex

7. Q2plt3fs05

8. 6-chloro-2-cyclohexyl-3-oxo-5-isoindolinesulfonamide

9. M & B 8430

10. 1h-isoindole-5-sulfonamide, 6-chloro-2-cyclohexyl-2,3-dihydro-3-oxo-

11. 5-chloro-2-cyclohexyl-1-oxo-6-sulphamoylisoindoline

12. 6-chloro-2-cyclohexyl-3-oxoisoindoline-5-sulfonamide

13. Flonatril; Klorex; Nefrolan; Rp 12833

14. 5-isoindolinesulfonamide, 6-chloro-2-cyclohexyl-3-oxo-

15. 12833 R.p.

16. 1h-isoindole-5-sulfonamide, 2,3-dihydro-6-chloro-2-cyclohexyl-3-oxo-

17. Cloresolone [dcit]

18. Clorexolonum [inn-latin]

19. Clorexolona [inn-spanish]

20. Cloresolone

21. Clorexolona

22. Clorexolonum

23. Clorexolone [usan:inn:ban]

24. Einecs 218-342-6

25. Brn 0493411

26. Clorexolone [mi]

27. Clorexolone [inn]

28. Clorexolone [jan]

29. Clorexolone [usan]

30. Unii-q2plt3fs05

31. Clorexolone [mart.]

32. Dsstox_cid_31472

33. Dsstox_rid_97357

34. Dsstox_gsid_57683

35. Clorexolone [who-dd]

36. Schembl310673

37. Clorexolone (jan/usan/inn)

38. Zinc1199

39. 6-chloro-2-cyclohexyl-3-oxo-1h-isoindole-5-sulfonamide

40. Chembl2106167

41. Dtxsid4057683

42. Chebi:31421

43. Tox21_113742

44. 6-chloro-2-cyclohexyl-2,3-dihydro-3-oxo-1h-isoindole-5-sulfonamide

45. Db13617

46. Ncgc00253608-01

47. 12833 Rp

48. Rp 12833

49. Rp-12833

50. Cas-2127-01-7

51. D01436

52. 5-22-07-00591 (beilstein Handbook Reference)

53. J-013964

54. Q5135140

55. 6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro- 1h-isoindole-5-sulfonamide

2.4 Create Date
2005-03-28
3 Chemical and Physical Properties
Molecular Weight 328.8 g/mol
Molecular Formula C14H17ClN2O3S
XLogP32
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass328.0648413 g/mol
Monoisotopic Mass328.0648413 g/mol
Topological Polar Surface Area88.8 Ų
Heavy Atom Count21
Formal Charge0
Complexity513
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

C - Cardiovascular system

C03 - Diuretics

C03B - Low-ceiling diuretics, excl. thiazides

C03BA - Sulfonamides, plain

C03BA12 - Clorexolone


ABOUT THIS PAGE

Looking for 2127-01-7 / Clorexolone API manufacturers, exporters & distributors?

Clorexolone manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Clorexolone API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Clorexolone manufacturer or Clorexolone supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Clorexolone manufacturer or Clorexolone supplier.

PharmaCompass also assists you with knowing the Clorexolone API Price utilized in the formulation of products. Clorexolone API Price is not always fixed or binding as the Clorexolone Price is obtained through a variety of data sources. The Clorexolone Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Clorexolone

Synonyms

Chlorexolone, 2127-01-7, Clorexolon, Flonatril, Nefrolan, Klorex

Cas Number

2127-01-7

Unique Ingredient Identifier (UNII)

Q2PLT3FS05

About Clorexolone

Clorexolone is a sulfonamide-based diuretic with thiazide-like activity. Cloreloxone has actions similar to that of thiazide diuretics.

DSSTox_CID_31472 Manufacturers

A DSSTox_CID_31472 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of DSSTox_CID_31472, including repackagers and relabelers. The FDA regulates DSSTox_CID_31472 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. DSSTox_CID_31472 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

DSSTox_CID_31472 Suppliers

A DSSTox_CID_31472 supplier is an individual or a company that provides DSSTox_CID_31472 active pharmaceutical ingredient (API) or DSSTox_CID_31472 finished formulations upon request. The DSSTox_CID_31472 suppliers may include DSSTox_CID_31472 API manufacturers, exporters, distributors and traders.

click here to find a list of DSSTox_CID_31472 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

DSSTox_CID_31472 USDMF

A DSSTox_CID_31472 DMF (Drug Master File) is a document detailing the whole manufacturing process of DSSTox_CID_31472 active pharmaceutical ingredient (API) in detail. Different forms of DSSTox_CID_31472 DMFs exist exist since differing nations have different regulations, such as DSSTox_CID_31472 USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A DSSTox_CID_31472 DMF submitted to regulatory agencies in the US is known as a USDMF. DSSTox_CID_31472 USDMF includes data on DSSTox_CID_31472's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The DSSTox_CID_31472 USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of DSSTox_CID_31472 suppliers with USDMF on PharmaCompass.

DSSTox_CID_31472 GMP

DSSTox_CID_31472 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of DSSTox_CID_31472 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right DSSTox_CID_31472 GMP manufacturer or DSSTox_CID_31472 GMP API supplier for your needs.

DSSTox_CID_31472 CoA

A DSSTox_CID_31472 CoA (Certificate of Analysis) is a formal document that attests to DSSTox_CID_31472's compliance with DSSTox_CID_31472 specifications and serves as a tool for batch-level quality control.

DSSTox_CID_31472 CoA mostly includes findings from lab analyses of a specific batch. For each DSSTox_CID_31472 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

DSSTox_CID_31472 may be tested according to a variety of international standards, such as European Pharmacopoeia (DSSTox_CID_31472 EP), DSSTox_CID_31472 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (DSSTox_CID_31472 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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