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Chemistry

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Also known as: Act-541468a, Act-541468 hydrochloride, Nemorexant hydrochloride, Quviviq, 9x9581n56r, 1792993-84-0
Molecular Formula
C23H24Cl2N6O2
Molecular Weight
487.4  g/mol
InChI Key
HJVGDXBEMFHGKI-BQAIUKQQSA-N
FDA UNII
9X9581N56R

Daridorexant Hydrochloride
1 2D Structure

Daridorexant Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(2S)-2-(5-chloro-4-methyl-1H-benzimidazol-2-yl)-2-methylpyrrolidin-1-yl]-[5-methoxy-2-(triazol-2-yl)phenyl]methanone;hydrochloride
2.1.2 InChI
InChI=1S/C23H23ClN6O2.ClH/c1-14-17(24)6-7-18-20(14)28-22(27-18)23(2)9-4-12-29(23)21(31)16-13-15(32-3)5-8-19(16)30-25-10-11-26-30;/h5-8,10-11,13H,4,9,12H2,1-3H3,(H,27,28);1H/t23-;/m0./s1
2.1.3 InChI Key
HJVGDXBEMFHGKI-BQAIUKQQSA-N
2.1.4 Canonical SMILES
CC1=C(C=CC2=C1N=C(N2)C3(CCCN3C(=O)C4=C(C=CC(=C4)OC)N5N=CC=N5)C)Cl.Cl
2.1.5 Isomeric SMILES
CC1=C(C=CC2=C1N=C(N2)[C@@]3(CCCN3C(=O)C4=C(C=CC(=C4)OC)N5N=CC=N5)C)Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
9X9581N56R
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Act-541468a

2. Act-541468 Hydrochloride

3. Nemorexant Hydrochloride

4. Quviviq

5. 9x9581n56r

6. 1792993-84-0

7. Unii-9x9581n56r

8. Daridorexant Hydrochloride [usan]

9. Methanone, ((2s)-2-(6-chloro-7-methyl-1h-benzimidazol-2-yl)-2-methyl-1-pyrrolidinyl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)-, Hydrochloride (1:1)

10. Chembl4650216

11. Schembl16767284

12. Ex-a7813

13. Daridorexant Hydrochloride [jan]

14. Ts-09376

15. Daridorexant Hydrochloride [who-dd]

16. ((2s)-2-(5-chloro-4-methyl-1h-benzimidazol-2-yl)-2-methylpyrrolidin-1-yl)(5- Methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone Hydrochloride (1:1)

17. ((2s)-2-(5-chloro-4-methyl-1h-benzimidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone Hydrochloride (1:1)

18. ((2s)-2-(5-chloro-4-methyl-1h-benzimidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone Monohydrochloride

19. (s)-(2-(5-chloro-4-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone Hydrochloride

2.4 Create Date
2015-06-29
3 Chemical and Physical Properties
Molecular Weight 487.4 g/mol
Molecular Formula C23H24Cl2N6O2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area88.9
Heavy Atom Count33
Formal Charge0
Complexity693
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Indication

Quviviq is indicated for the treatment of adult patients with insomnia characterised by symptoms present for at least 3 months and considerable impact on daytime functioning.


5 Pharmacology and Biochemistry
5.1 ATC Code

N05


API SUPPLIERS

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01

Chemtour

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Specialty & Agro Chemical
Not Confirmed
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Chemtour

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Specialty & Agro Chemical
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Amadis Chemical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Specialty & Agro Chemical
Not Confirmed
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Amadis Chemical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Specialty & Agro Chemical
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FandaChem

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Specialty & Agro Chemical
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FandaChem

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Specialty & Agro Chemical
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Sandoo Pharmaceuticals and Chemcia...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Specialty & Agro Chemical
Not Confirmed
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Sandoo Pharmaceuticals and Chemcia...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Specialty & Agro Chemical
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SMS Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Specialty & Agro Chemical
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Listed Suppliers

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Specialty & Agro Chemical
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Daridorexant Hydrochloride

About the Company : Amadis Chemical Company Limited has become a professional innovative chemical product manufacturer and a technical service provider. We're specialists in sales, manufacture, and ...

Amadis Chemical Company Limited has become a professional innovative chemical product manufacturer and a technical service provider. We're specialists in sales, manufacture, and service covering building block, key intermediate and API especially for the service of process development, pilot scale and manufacture. And the core products are Carbohydrates, Nucleosides, Nucleotides, Phosphonamidites, APIS and Pharmaceutical intermediates.
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02

Chemtour

China
Specialty & Agro Chemical
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Chemtour

China
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Daridorexant Hydrochloride

About the Company : Established in 2014, Chemtour specializes in supplying pharmaceutical raw materials and chemicals to both domestic and international clients. Our product range comprises five serie...

Established in 2014, Chemtour specializes in supplying pharmaceutical raw materials and chemicals to both domestic and international clients. Our product range comprises five series, namely peptide chemicals & amino acids, nucleotides & nucleic acids, building blocks, advanced intermediates (primarily orphan drugs), and functional chemicals. Guided by the vision of "delivering top-notch service in the health industry" and the mission of "promoting healthier and better lives," we offer comprehensive capabilities ranging from lab samples to pilot-scale and commercial production through CRO and CMO services.
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FandaChem

China
Specialty & Agro Chemical
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FandaChem

China
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Daridorexant Hydrochloride

About the Company : FandaChem, headquartered in Hangzhou, China, is a reputable supplier and exporter of chemicals with a focus on delivering high-quality products. Our expertise lies in exporting a w...

FandaChem, headquartered in Hangzhou, China, is a reputable supplier and exporter of chemicals with a focus on delivering high-quality products. Our expertise lies in exporting a wide range of superior chemicals, specializing in areas such as agrochemicals, flavors, fragrances, pharmaceuticals, intermediates, paints, resins, plastics, surfactants, polymers, cosmetics, and more. Dedicated to being your dependable partner in China, FandaChem is devoted to offering top-notch products, competitive prices, and excellent service to meet the needs of our customers.
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Daridorexant Hydrochloride

About the Company : Sandoo Pharmaceuticals and Chemcials Co.,Ltd was established in 2009, with a young and active team, located in Ningbo, China. Specializes in exporting and importing pharmaceutica...

Sandoo Pharmaceuticals and Chemcials Co.,Ltd was established in 2009, with a young and active team, located in Ningbo, China. Specializes in exporting and importing pharmaceutical intermediates and chemical products as well as active pharmaceutical ingredients.
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Specialty & Agro Chemical
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Daridorexant Hydrochloride

About the Company : SMS Pharmaceuticals Ltd. is a global player in API manufacturing having a strong research and manufacturing team supported by state of the art facilities. What started off as a sin...

SMS Pharmaceuticals Ltd. is a global player in API manufacturing having a strong research and manufacturing team supported by state of the art facilities. What started off as a single facility - single product manufacturing company in 1990 grew to be a multi-location group having product list spreading across an array of therapeutic segments. SMS was given the export house status in the year 1997-98. SMS is currently a listed company having ever appreciating international and domestic customer base.
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API Reference Price

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02-Mar-2024
02-Mar-2024
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Looking for 1792993-84-0 / Daridorexant Hydrochloride API manufacturers, exporters & distributors?

Daridorexant Hydrochloride manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Daridorexant Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Daridorexant Hydrochloride manufacturer or Daridorexant Hydrochloride supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Daridorexant Hydrochloride manufacturer or Daridorexant Hydrochloride supplier.

PharmaCompass also assists you with knowing the Daridorexant Hydrochloride API Price utilized in the formulation of products. Daridorexant Hydrochloride API Price is not always fixed or binding as the Daridorexant Hydrochloride Price is obtained through a variety of data sources. The Daridorexant Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Daridorexant Hydrochloride

Synonyms

Act-541468a, Act-541468 hydrochloride, Nemorexant hydrochloride, Quviviq, 9x9581n56r, 1792993-84-0

Cas Number

1792993-84-0

Unique Ingredient Identifier (UNII)

9X9581N56R

Daridorexant Hydrochloride Manufacturers

A Daridorexant Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Daridorexant Hydrochloride, including repackagers and relabelers. The FDA regulates Daridorexant Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Daridorexant Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Daridorexant Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Daridorexant Hydrochloride Suppliers

A Daridorexant Hydrochloride supplier is an individual or a company that provides Daridorexant Hydrochloride active pharmaceutical ingredient (API) or Daridorexant Hydrochloride finished formulations upon request. The Daridorexant Hydrochloride suppliers may include Daridorexant Hydrochloride API manufacturers, exporters, distributors and traders.

click here to find a list of Daridorexant Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Daridorexant Hydrochloride GMP

Daridorexant Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Daridorexant Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Daridorexant Hydrochloride GMP manufacturer or Daridorexant Hydrochloride GMP API supplier for your needs.

Daridorexant Hydrochloride CoA

A Daridorexant Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Daridorexant Hydrochloride's compliance with Daridorexant Hydrochloride specifications and serves as a tool for batch-level quality control.

Daridorexant Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Daridorexant Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Daridorexant Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Daridorexant Hydrochloride EP), Daridorexant Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Daridorexant Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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