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Chemistry

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Also known as: Azd7594, Azd-7594, 1196509-60-0, 3-(5-((1r,2s)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propoxy)-1h-indazol-1-yl)-n-((r)-tetrahydrofuran-3-yl)benzamide, 3-[5-[(1r,2s)-2-(2,2-difluoropropanoylamino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]indazol-1-yl]-n-[(3r)-oxolan-3-yl]benzamide, Az13189620
Molecular Formula
C32H32F2N4O6
Molecular Weight
606.6  g/mol
InChI Key
ZZWJKLGCDHYVMB-BWGXUDETSA-N

AZD7594
1 2D Structure

AZD7594

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[5-[(1R,2S)-2-(2,2-difluoropropanoylamino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]indazol-1-yl]-N-[(3R)-oxolan-3-yl]benzamide
2.1.2 InChI
InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27)44-25-7-8-26-22(15-25)17-35-38(26)24-5-3-4-21(14-24)30(39)37-23-10-11-41-18-23/h3-9,14-17,19,23,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23+,29-/m0/s1
2.1.3 InChI Key
ZZWJKLGCDHYVMB-BWGXUDETSA-N
2.1.4 Canonical SMILES
CC(C(C1=CC2=C(C=C1)OCCO2)OC3=CC4=C(C=C3)N(N=C4)C5=CC=CC(=C5)C(=O)NC6CCOC6)NC(=O)C(C)(F)F
2.1.5 Isomeric SMILES
C[C@@H]([C@@H](C1=CC2=C(C=C1)OCCO2)OC3=CC4=C(C=C3)N(N=C4)C5=CC=CC(=C5)C(=O)N[C@@H]6CCOC6)NC(=O)C(C)(F)F
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 3-(5-((1r,2s)-2-((2,2-difluoropropanoyl)amino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy)-1h-indazol-1-yl)-n-((3r)-tetrahydro-3-furanyl)benzamide

2. Azd7594

3. Benzamide, 3-(5-((1r,2s)-2-((2,2-difluoro-1-oxopropyl)amino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy)-1h-indazol-1-yl)-n-((3r)-tetrahydro-3-furanyl)-

2.2.2 Depositor-Supplied Synonyms

1. Azd7594

2. Azd-7594

3. 1196509-60-0

4. 3-(5-((1r,2s)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propoxy)-1h-indazol-1-yl)-n-((r)-tetrahydrofuran-3-yl)benzamide

5. 3-[5-[(1r,2s)-2-(2,2-difluoropropanoylamino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]indazol-1-yl]-n-[(3r)-oxolan-3-yl]benzamide

6. Az13189620

7. Azd 7594

8. Gtpl9325

9. Schembl1456757

10. Chembl3666807

11. Bdbm141372

12. Amy16844

13. Ex-a1939

14. Akos037648545

15. Compound 15m [pmid: 28937774]

16. Bs-14536

17. Hy-111453

18. Cs-0040937

19. Us8916600, 6

20. Az13189620az13189620

21. 3-{5-[(1r,2s)-2-(2,2-difluoropropanamido)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]-1h-indazol-1-yl}-n-[(3r)-oxolan-3-yl]benzamide

2.3 Create Date
2012-11-30
3 Chemical and Physical Properties
Molecular Weight 606.6 g/mol
Molecular Formula C32H32F2N4O6
XLogP34.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Exact Mass606.22899108 g/mol
Monoisotopic Mass606.22899108 g/mol
Topological Polar Surface Area113 Ų
Heavy Atom Count44
Formal Charge0
Complexity1010
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1196509-60-0 / AZD7594 API manufacturers, exporters & distributors?

AZD7594 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of AZD7594 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right AZD7594 manufacturer or AZD7594 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred AZD7594 manufacturer or AZD7594 supplier.

PharmaCompass also assists you with knowing the AZD7594 API Price utilized in the formulation of products. AZD7594 API Price is not always fixed or binding as the AZD7594 Price is obtained through a variety of data sources. The AZD7594 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

AZD7594

Synonyms

Azd-7594, 1196509-60-0, 3-(5-((1r,2s)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propoxy)-1h-indazol-1-yl)-n-((r)-tetrahydrofuran-3-yl)benzamide, 3-[5-[(1r,2s)-2-(2,2-difluoropropanoylamino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]indazol-1-yl]-n-[(3r)-oxolan-3-yl]benzamide, Az13189620, Azd 7594

Cas Number

1196509-60-0

AZD7594 Manufacturers

A AZD7594 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of AZD7594, including repackagers and relabelers. The FDA regulates AZD7594 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. AZD7594 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

AZD7594 Suppliers

A AZD7594 supplier is an individual or a company that provides AZD7594 active pharmaceutical ingredient (API) or AZD7594 finished formulations upon request. The AZD7594 suppliers may include AZD7594 API manufacturers, exporters, distributors and traders.

AZD7594 GMP

AZD7594 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of AZD7594 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right AZD7594 GMP manufacturer or AZD7594 GMP API supplier for your needs.

AZD7594 CoA

A AZD7594 CoA (Certificate of Analysis) is a formal document that attests to AZD7594's compliance with AZD7594 specifications and serves as a tool for batch-level quality control.

AZD7594 CoA mostly includes findings from lab analyses of a specific batch. For each AZD7594 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

AZD7594 may be tested according to a variety of international standards, such as European Pharmacopoeia (AZD7594 EP), AZD7594 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (AZD7594 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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