

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Varegacestat
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Cardiac Liability Study of Varegacestat in Healthy Participants
Details : Varegacestat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 03, 2025
Lead Product(s) : Varegacestat
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Varegacestat
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 Mass Balance Study of Varegacestat
Details : Varegacestat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 25, 2025
Lead Product(s) : Varegacestat
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Varegacestat
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Varegacestat Hepatic Impairment Study
Details : Varegacestat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Liver Diseases.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 24, 2025
Lead Product(s) : Varegacestat
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : J.P. Morgan
Deal Size : $172.5 million
Deal Type : Public Offering
Immunome Closes Upsized Public Offering, Underwriters’ Option Fully Exercised
Details : The proceeds will fund the clinical and preclinical development of pipeline assets, including AL102 (varegacestat), a gamma secretase and pan-Notch inhibitor, with potential antineoplastic activity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 31, 2025
Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : J.P. Morgan
Deal Size : $172.5 million
Deal Type : Public Offering

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Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
Immunome Announces Proposed Public Offering of Common Stock
Details : The proceeds will fund the clinical and preclinical development of pipeline assets, including AL102 (varegacestat), a gamma secretase and pan-Notch inhibitor, with potential antineoplastic activity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 29, 2025
Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering

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Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
Immunome Announces Pricing of Upsized Public Offering of Common Stock
Details : The proceeds will fund the clinical and preclinical development of pipeline assets, including AL102 (varegacestat), a gamma secretase and pan-Notch inhibitor, with potential antineoplastic activity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 29, 2025
Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering

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Lead Product(s) : Varegacestat
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Varegacestat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 07, 2024
Lead Product(s) : Varegacestat
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Immunome
Deal Size : $87.5 million
Deal Type : Acquisition
Immunome Completes Acquisition of AL102 for Desmoid Tumors Treatment
Details : Through the acquisition, Immunome have the access for AL102, a small molecule gamma secretase inhibitor currently being evaluated for desmoid tumors, and related drug candidate AL101 from Ayala.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $20.0 million
March 26, 2024
Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Immunome
Deal Size : $87.5 million
Deal Type : Acquisition

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Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable
Ayala Completes Enrollment in Phase 3 RINGSIDE Study of AL102 for Desmoid Tumors
Details : AL102 is an inhibitor of gamma secretase-mediated notch signaling. It is being evaluated in phase 3 clinical trials for the treatment of desmoid tumors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 20, 2024
Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Bristol Myers Squibb
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Immunome
Deal Size : $87.5 million
Deal Type : Acquisition
Immunome to Acquire AL102 for Desmoid Tumors from Ayala Pharmaceuticals
Details : Through the acquisition, Immunome will have the access for AL102, a small molecule gamma secretase inhibitor currently being evaluated for desmoid tumors, and related drug candidate AL101 from Ayala.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $20.0 million
February 06, 2024
Lead Product(s) : Varegacestat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Immunome
Deal Size : $87.5 million
Deal Type : Acquisition
