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Find Clinical Drug Pipeline Developments & Deals by TRexBio
Under the collaboration, Johnson & Johnson Innovative Medicine has exercised the first of its options for an exclusive license to develop and commercialize novel target that aim to address unmet needs in immune-mediated disease, arising out of the collaboration.
TRB-061, an agonist targeting TNF receptor 2 (TNFR2). TRB-061 expands regulatory T cells (Tregs) to restore homeostasis in the tissue at the site of inflammation.
Collaboration leverages TRexBio’s Deep Biology platform, which mapsTreg behavior in human tissue to identify and target immune-regulatory pathways. Programs that have been identified and characterized leveraging TRex’s Deep Biology platform are TRB-031, TRB-041, and TRB-051.
Proceeds from the financing will be used to expand the company’s unique discovery platform that maps human tissue regulatory T cell (Treg) behavior to dysregulation in diseases, including its lead asset TRB-051.