Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Treosulfan,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Strategic cornerstone: FDA approves treosulfan for alloHSCT
Details : Grafapex (treosulfan) is now approved by FDA for the treatment of adult and pediatric patients aged 1 year and older with acute myeloid leukemia.
Product Name : Grafapex
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
January 23, 2025
Lead Product(s) : Treosulfan,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Medexus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Medexus and medac Conclude Negotiations to Amend US Treosulfan Agreement
Details : The fourth amendment adjusts the unpaid regulatory milestone payments upon an FDA approval of Grafapex (treosulfan).
Product Name : Grafapex
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
December 02, 2024
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Medexus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Syneos Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics
Details : Undisclosed
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
September 09, 2022
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Syneos Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Treosulfan,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Medexus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Treosulfan will be marketed in Canada under the brand name Trecondyv® and indicated in combination with fludarabine as part of a conditioning treatment prior to allogeneic hematopoietic stem cell transplantation (“allo-HSCT”).
Product Name : Trecondyv
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
July 12, 2021
Lead Product(s) : Treosulfan,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Medexus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Treosulfan,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Medexus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Medexus and Medac Enter Into a License Agreement for Treosulfan, in the United States
Details : Medac intends to leverage its strong, existing commercial infrastructure in the United States to address the underserved allo-HSCT market through its commercialization of treosulfan.
Product Name : Trecondyv
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
February 02, 2021
Lead Product(s) : Treosulfan,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Medexus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Treosulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Celerion | Venn Life Sciences | Syneos Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
January 29, 2015
Lead Product(s) : Treosulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Celerion | Venn Life Sciences | Syneos Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Celerion | Syneos Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies
Details : Undisclosed
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
January 07, 2015
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Celerion | Syneos Health
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Dose-range Finding Treosulfan-based Conditioning
Details : Undisclosed
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
February 05, 2010
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Treosulfan Based Conditioning Acute Myeloid Leukaemia (AML)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
February 05, 2010
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Treosulfan Based Conditioning Myelodysplastic Syndrome (MDS)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
February 04, 2010
Lead Product(s) : Treosulfan
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable