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            Details:

            TGN-S11 is an E5 oncogene protein Inhibitor small molecule drug candidate, which is being evaluated in combination with pembrolizumab for the treatment of HPV-Induced Cancer.

            Lead Product(s): TGN-S11,Pembrolizumab

            Therapeutic Area: Oncology Product Name: TGN-S11

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 12, 2023

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            Details:

            TGN-S11 is a small molecule that is inhibits the E5 oncogene of HPV, which is investigated for the treatment of Human Papillomavirus(HPV) Induced Cancer.

            Lead Product(s): TGN-S11,Pembrolizumab

            Therapeutic Area: Oncology Product Name: TGN-S11

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 06, 2023

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            Details:

            TGN-S11 is a small molecule that is inhibits the E5 oncogene of HPV, which is investigated for the treatment of Human Papillomavirus(HPV) Induced Cancer.

            Lead Product(s): TGN-S11,Pembrolizumab

            Therapeutic Area: Oncology Product Name: TGN-S11

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 10, 2023

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            Details:

            TGN-S11 is a Small Molecule that is inhibits the E5 oncogene of HPV, which is investigated for the treatment of Human Papillomavirus(HPV) Induced Cancer.

            Lead Product(s): TGN-S11,Pembrolizumab

            Therapeutic Area: Oncology Product Name: TGN-S11

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 30, 2023

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            Details:

            TGN-S11 was initially developed and approved as anti-microbial drug. It has been discovered that it decreases the growth of HPV+ tumor cells and improves survival in mice with HPV+ tumors.

            Lead Product(s): TGN-S11

            Therapeutic Area: Infections and Infectious Diseases Product Name: TGN-S11

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 28, 2023

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            Details:

            Toragen is ready to begin a Phase I Clinical trial of single agent TGN-S11 in 12-15 patients with HPV associated malignancies. This will be a dose escalation study with the primary endpoint being feasibility, safety, and toxicity.

            Lead Product(s): TGN-S11

            Therapeutic Area: Infections and Infectious Diseases Product Name: TGN-S11

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 07, 2022

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