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Find Clinical Drug Pipeline Developments & Deals for Revlimid
Sarclisa (isatuximab) is a CD38 monoclonal antibody in combination with standard-of-care bortezomib, lenalidomide and dexamethasone is being evaluated in newly diagnosed multiple myeloma not eligible for transplant.
Lenalidomide, a therapeutic equivalent generic version of REVLIMID, and a thalidomide analogue, caused limb abnormalities in developmental monkey study similar to birth defects caused by thalidomide in humans.
Dr. Reddy received ANDA approval for lenalidomide capsules, in 2.5 mg and 20 mg strengths, and tentative approval for 5 mg, 10 mg, 15 mg, and 25 mg strengths, a therapeutic equivalent generic version of Revlimid.
Kyprolis-Generic (carfilzomib) is a proteasome inhibitor, small molecule drug candidate, which is indicated for the treatment of patients with relapsed or refractory multiple myeloma as monotherapy or in combination with dexamethasone or with lenalidomide plus dexamethasone.
STAR-LLD is a continuous delivery lenalidomide (LLD), which is under clinical development to expand and replace the standard of care for the most common blood cancers, multiple myeloma (MM), and chronic lymphocytic leukemia (CLL).
EO2463, an innovative off-the-shelf immunotherapy candidate, is being assessed in early-stage clinical trials with patients for the treatment of follicular lymphoma and marginal zone lymphoma in combination with lenalidomide/rituximab.
ALX Oncology lead product candidate ALX148 (evorpacept) in combination with Rituximab and Lenalidomide is being evaluated with patients for the treatment of patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Pfizer's Adcetris (brentuximab vedotin), CD30 inhibitor, which is being evaluated in Phase III clinical trial studies in combination with Lenalidomide and Rituximab for the treatment of Relapsed/Refractory Diffuse Large B-cell Lymphoma.
Johnson-approved product Darzalex (daratumumab), which is a CD38 inhibitor, currently it is being evaluated in Phase III clinical trials in combination with bortezomib, lenalidomide, dexamethasone for the treatment of multiple myeloma.
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