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Inapplicable"},{"orgOrder":0,"company":"Apellis Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"C3 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Apellis Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Apellis Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Apellis Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"C3 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Apellis Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Apellis Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Apellis Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Inapplicable","leadProduct":"Pegcetacoplan","moa":"C3 receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Apellis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Apellis Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Apellis Pharmaceuticals \/ 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Find Ophthalmology Clinical Drug Pipeline Developments & Deals for Pegcetacoplan

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                          01

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          January 27, 2025

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          October 06, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          September 20, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy. It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          June 28, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          April 26, 2024

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre (pegcetacoplan injection) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          December 14, 2023

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre™ (pegcetacoplan injection) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          April 21, 2023

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Syfovre™ (pegcetacoplan injection) is the first and only approved therapy for geographic atrophy (GA). It targets C3 to provide comprehensive control of the complement cascade, part of the body’s immune system.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          February 17, 2023

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : Two post hoc analyses of microperimetry data showed positive trends with increasing effects over time, demonstrating both monthly and every-other-month (EOM) APL-2 (pegcetacoplan) treatment preserved visual function of retinal cells near the GA lesion bo...

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          September 30, 2022

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AGGSpend
                          Not Confirmed
                          AGGSpend
                          Not Confirmed

                          Details : In a pre-specified analysis of GA lesion growth over 24 months, both monthly and every-other-month (EOM) APL-2 (pegcetacoplan) showed clinically meaningful reduction in GA lesion growth from baseline compared to sham.

                          Product Name : Syfovre

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          August 24, 2022

                          Lead Product(s) : Pegcetacoplan

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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