

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Pegargiminase,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Polaris Group
Deal Size : Undisclosed
Deal Type : Agreement
Er-Kim, Polaris Ink Deal to Sell Pegargiminase for MPM in EMEA
Details : Under the agreement, Polaris will holds the rights for commercialization of ADI-PEG 20 (pegargiminase). It is being evaluated in late-satge for the treatment of malignant pleural mesothelioma
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Undisclosed
April 15, 2025
Lead Product(s) : Pegargiminase,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Polaris Group
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Pegargiminase,Docetaxel,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADI-PEG 20 (pegargiminase) is an Arginine Degrader Enzyme drug candidate, which is currently being evaluating clinical trial studies with patients for the treatment of Leiomyosarcoma.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
December 04, 2023
Lead Product(s) : Pegargiminase,Docetaxel,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADI-PEG 20 (pegylated arginine deiminase, pegargiminase) is designed to deplete the external supply of arginine, and is being investigated for Non-Alcoholic Steatohepatitis (NASH).
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
November 29, 2023
Lead Product(s) : Pegargiminase
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADI-PEG 20 (pegargiminase) ia arginie degrader, which is being evaluated in phase 2/3 clinical trials in combination with cisplatin & pemetrexed for the treatment of malignant pleural mesothelioma.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
November 16, 2023
Lead Product(s) : Pegargiminase,Cisplatin,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Polaris Group
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADI-PEG 20 (pegargiminase) is designed to deplete the external supply of arginine, which causes arginine-dependent cancer cells to die while leaving the patient’s normal cells unharmed, which is investigated for glioblastoma.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
August 15, 2023
Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Polaris Group
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of ADI-PEG 20 Versus Placebo in Subjects With NASH
Details : ADI-PEG 20 is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
May 06, 2023
Lead Product(s) : Pegargiminase
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Children's Discovery Institute | Polaris Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
ADI-PEG20, Obesity and Prediabetes
Details : ADI-PEG 20 is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
April 25, 2023
Lead Product(s) : Pegargiminase
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Children's Discovery Institute | Polaris Pharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Polaris Group
Deal Size : Inapplicable
Deal Type : Inapplicable
Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma
Details : ADI PEG20 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Sarcoma.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
April 14, 2023
Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Polaris Group
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADI PEG20 is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Sarcoma.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
February 03, 2023
Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Polaris Group
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADI-PEG 20 is a Enzyme drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
November 15, 2022
Lead Product(s) : Pegargiminase
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Polaris Group
Deal Size : Inapplicable
Deal Type : Inapplicable
