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Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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            Lead Product(s): Parathyroid Hormone

            Therapeutic Area: Musculoskeletal Product Name: PTH

            Highest Development Status: Preclinical Product Type: Peptide

            Partner/Sponsor/Collaborator: BofA Securities

            Deal Size: $69.0 million Upfront Cash: Undisclosed

            Deal Type: Series E Financing December 10, 2020

            Details:

            Rani Therapeutics platform technology converts injectable drugs like PTH and adalimumab into pills. Rani has conducted early human studies with adalimumab and exenatide to confirm high bioavailability with the Rani delivery approach.

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            Lead Product(s): KER-012

            Therapeutic Area: Musculoskeletal Product Name: KER-012

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 11, 2020

            Details:

            In Preclinical Studies, KER-012 Increased Trabecular Bone by Reducing Bone Catabolism and Enhancing Anabolism.

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            Lead Product(s): Calcium Alpha-Ketoglutarate

            Therapeutic Area: Musculoskeletal Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 02, 2020

            Details:

            The multi-year study, conducted by the Buck Institute for Research on Aging in aged mice, found that calcium alpha-ketoglutarate (Ca-AKG), a stable form of alpha-ketoglutarate, promotes longer, healthier life associated with a decrease in levels of inflammatory cytokines.