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            Lead Product(s): ARO-XDH

            Therapeutic Area: Musculoskeletal Product Name: ARO-XDH

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Horizon Therapeutics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration June 21, 2021

            Details:

            Arrowhead will conduct all activities through preclinical stages of development of the siRNA therapeutic, ARO-XDH. Horizon will receive a worldwide exclusive license to ARO-XDH and will be wholly responsible for clinical development and commercialization.

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            Lead Product(s): AM3101

            Therapeutic Area: Musculoskeletal Product Name: AM3101

            Highest Development Status: Preclinical Product Type: Undisclosed

            Partner/Sponsor/Collaborator: Photon Fund

            Deal Size: $4.0 million Upfront Cash: Undisclosed

            Deal Type: Financing March 25, 2021

            Details:

            The proceeds from the financing will enable Amplicore to complete the preclinical development of its two leading products, AM3101 and AM1101, and position the company for the next round of financing.