

Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger
Aeterna Zentaris and Ceapro Complete Merger Transaction
Details : The combined company will focus on the development of AEZS-130 (macimorelin), a ghrelin receptor agonist and a small molecule that stimulates the secretion of growth hormone from the pituitary gland.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 03, 2024
Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger
Details : The combined company will focus on the development of AEZS-130 (macimorelin), a ghrelin receptor agonist and a small molecule that stimulates the secretion of growth hormone from the pituitary gland.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 14, 2023
Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger

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Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Macimorelin (Macrilen®; GHRYVELIN™), a ghrelin agonist, is an orally active small molecule that stimulates the secretion of growth hormone from the pituitary gland.
Product Name : Macrilen
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 05, 2023
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Termination
Details : Under the Commercial License, Novo Nordisk was granted an exclusive license for the development, manufacturing, registration and commercialization of Macrilen™ (macimorelin) in the U.S. and Canada.
Product Name : Macrilen
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 29, 2022
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Termination

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Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Macimorelin is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Dwarfism, Pituitary.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 08, 2021
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : H.C. Wainwright & Co
Deal Size : $12.0 million
Deal Type : Public Offering
Aeterna Zentaris Announces Pricing of $12 Million Public Offering
Details : The Company intends to use the net proceeds of this offering for general corporate purposes, which includes funding of a pediatric clinical trial in the E.U. and U.S. for Macrilen, the investigation of further therapeutic uses of macimorelin.
Product Name : Macrilen
Product Type : Miscellaneous
Upfront Cash : Undisclosed
July 01, 2020
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : H.C. Wainwright & Co
Deal Size : $12.0 million
Deal Type : Public Offering

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Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aeterna Zentaris Announces Positive Results In Dose-Finding Pediatric Study Of Macimorelin
Details : Positive results provide clinical framework to advance the Company’s Pediatric Investigation Plan for macimorelin as a growth hormone deficiency diagnostic.
Product Name : Macrilen
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 06, 2020
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency
Details : Macimorelin is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Pituitary Anomalies-associated with Growth Hormone Deficiency.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 24, 2015
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Macimorelin
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Garcia, Jose M., MD, PhD
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Macimorelin is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Cancer Cachexia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 08, 2012
Lead Product(s) : Macimorelin
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Garcia, Jose M., MD, PhD
Deal Size : Inapplicable
Deal Type : Inapplicable
