
 
													
 
									 
															 
															Year
 
															DEALS // DEV.
 
															Country
 
															 
															Therapeutic Area
 
															Study Phase
 
															Deal Type
 
															Product Type
 
															Dosage Form
 
															Lead Product
 
															Target

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Lead Product(s) : Lysine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lyranda, a Breakthrough Cold Sore Treatment, is Now Available in the U.S.
Details : Lyranda (L-lysine) has antiviral effects by blocking the activity of arginine, which promotes the replication of the herpes simplex virus (HSV).
Product Name : Lyranda
Product Type : Amino Acid
Upfront Cash : Inapplicable
August 28, 2024
Lead Product(s) : Lysine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu Edotreotide,Everolimus,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Temasek Life Sciences Laboratory
Deal Size : $272.7 million
Deal Type : Financing
Details : The net financing will support the development of ITM’s broad Targeted Radionuclide Therapies oncology pipeline and enhance phase III clinical development for its lead pipeline candidate, ITM-11 (n.c.a. 177Lu-edotreotide) in gastroenteropancreatic neur...
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
June 05, 2023
Lead Product(s) : 177-Lu Edotreotide,Everolimus,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Temasek Life Sciences Laboratory
Deal Size : $272.7 million
Deal Type : Financing

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ITM-11 consists of two components: the medical radioisotope non-carrier-added lutetium-177 (n.c.a. 177Lu) and the targeting molecule edotreotide, a synthetic form of the peptide hormone somatostatin that targets neuroendocrine tumor-specific receptors.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
October 27, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ITM-11 (n.c.a. 177Lu-edotreotide), as first- or second-line treatment compared to best standard of care for patients with well-differentiated aggressive grade 2 and grade 3 somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
September 06, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ITM-11 is a Targeted Radionuclide Therapy consisting of the high-quality beta-emitting radioisotope, no-carrier-added lutetium-177 (n.c.a. 177Lu) combined with the tumor-specific targeting molecule edotreotide.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
June 15, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Indigenous Critical Infrastructure Fund Canada
Deal Size : $36.3 million
Deal Type : Financing
Details : The proceeds will be used for the finalization of the late-stage development of the lead candidate ITM-11 (n.c.a. 177Lu-edotreotide), a targeted radiopharmaceutical currently being evaluated in phase III for the treatment of gastroenteropancreatic neuroe...
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
March 22, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Indigenous Critical Infrastructure Fund Canada
Deal Size : $36.3 million
Deal Type : Financing

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ITM-11, a targeted radionuclide therapy consisting of high-quality radioisotope, no-carrier-added lutetium-177 combined with somatostatin analog edotreotide is best standard of care for patients with neuroendocrine tumors.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
March 09, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Grand Pharmaceutical Group Limited
Deal Size : $588.4 million
Deal Type : Licensing Agreement
ITM Receives Equity Investment of EUR 25 Million from Strategic Partner Grand Pharma
Details : The equity investment follows the licensing agreement between companies which provides GP with rights to develop, manufacture and commercialize ITM’s precision oncology radiopharmaceutical candidates, ITM-11 (n.c.a. 177Lu-edotreotide) and ITM-41 (n.c.a...
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
February 16, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Grand Pharmaceutical Group Limited
Deal Size : $588.4 million
Deal Type : Licensing Agreement

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ITM-11 (177Lu-edotreotide), a synthetic form of the peptide hormone somatostatin that targets neuroendocrine tumor-specific receptors demonstrated promising results in its trial for the treatment of hard-to-treat tumors.
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Inapplicable
January 19, 2022
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Grand Pharmaceutical Group Limited
Deal Size : $588.4 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, ITM grants GP an exclusive license for the ITM-11 (n.c.a. 177Lu-edotreotide) and ITM-41 (n.c.a. 177Lu-zoledronate), in the licensed territory and will support the supply of the pharmaceuticals needed for clinical and com...
Product Name : Undisclosed
Product Type : Radiolabeled Compound
Upfront Cash : Undisclosed
December 27, 2021
Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Grand Pharmaceutical Group Limited
Deal Size : $588.4 million
Deal Type : Licensing Agreement

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