Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Carfilzomib,Dexamethasone,Lenalidomide
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Kyprolis-Generic (carfilzomib) is a proteasome inhibitor, small molecule drug candidate, which is indicated for the treatment of patients with relapsed or refractory multiple myeloma as monotherapy or in combination with dexamethasone or with lenalidomid...
Product Name : Kyprolis-Generic
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 16, 2021
Lead Product(s) : Carfilzomib,Dexamethasone,Lenalidomide
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isatuximab,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CHMP issues positive opinion for second indication for Sarclisa in combination with carfilzomib and dexamethasone for adult patients with multiple myeloma who have received at least one prior therapy.
Product Name : Sarclisa
Product Type : Antibody
Upfront Cash : Inapplicable
February 26, 2021
Lead Product(s) : Isatuximab,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isatuximab,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sanofi's Sarclisa Cuts Death Risk In Mutiple Myeloma
Details : Addition of Sarclisa significantly reduced the risk of disease progression or death compared to carfilzomib and dexamethasone alone.
Product Name : Sarclisa
Product Type : Antibody
Upfront Cash : Inapplicable
December 05, 2020
Lead Product(s) : Isatuximab,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isatuximab,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sarclisa added to carfilzomib and dexamethasone (Sarclisa combination) reduced risk of disease progression or death by 47% versus standard of care carfilzomib and dexamethasone (Kd) alone.
Product Name : Sarclisa
Product Type : Antibody
Upfront Cash : Inapplicable
February 06, 2020
Lead Product(s) : Isatuximab,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Genentech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 14, 2016
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Genentech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 20, 2022
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Carfilzomib
Therapeutic Area : Undisclosed
Study Phase : Phase I/ Phase II
Sponsor : Immune Tolerance Network | Bristol Myers Squibb | PPD | Rho, Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Carfilzomib and Belatacept for Desensitization
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 24, 2021
Lead Product(s) : Carfilzomib
Therapeutic Area : Undisclosed
Highest Development Status : Phase I/ Phase II
Sponsor : Immune Tolerance Network | Bristol Myers Squibb | PPD | Rho, Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 12, 2021
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Maplirpacept,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : TTI-622 is a fusion protein that is designed to block the inhibitory activity of CD47, a molecule that is overexpressed by a wide variety of tumors.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
April 28, 2021
Lead Product(s) : Maplirpacept,Carfilzomib,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Oregon Health and Science University | Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 20, 2021
Lead Product(s) : Carfilzomib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Oregon Health and Science University | Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable