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proteasome","graph1":"Oncology","graph2":"Phase II","graph3":"Dana-Farber Cancer Institute","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Dana-Farber Cancer Institute \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Dana-Farber Cancer Institute \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"Mayo Clinic","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase II","graph3":"Mayo Clinic","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Mayo Clinic \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"7","companyTruncated":"Mayo Clinic \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"Memorial Sloan Kettering Cancer Center","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase I","graph3":"Memorial Sloan Kettering Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Memorial Sloan Kettering Cancer Center \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"6","companyTruncated":"Memorial Sloan Kettering Cancer Center \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"Intergroupe Francophone du Myelome","sponsor":"AXONAL | Nantes University Hospital | University Hospital, Grenoble | Euraxi Pharma | QPS Holdings | Bristol Myers Squibb | Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase II","graph3":"Intergroupe Francophone du Myelome","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Intergroupe Francophone du Myelome \/ AXONAL | Nantes University Hospital | University Hospital, Grenoble | Euraxi Pharma | QPS Holdings | Bristol Myers Squibb | Takeda Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Intergroupe Francophone du Myelome \/ AXONAL | Nantes University Hospital | University Hospital, Grenoble | Euraxi Pharma | QPS Holdings | Bristol Myers Squibb | Takeda Pharmaceutical"},{"orgOrder":0,"company":"Omar Nadeem, MD","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Omar Nadeem, MD","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Omar Nadeem, MD \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"7","companyTruncated":"Omar Nadeem, MD \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"Raija Silvennoinen","sponsor":"Nordic Myeloma Study Group | Bristol Myers Squibb | Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase II","graph3":"Raija Silvennoinen","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Raija Silvennoinen \/ Nordic Myeloma Study Group | Bristol Myers Squibb | Takeda Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Raija Silvennoinen \/ Nordic Myeloma Study Group | Bristol Myers Squibb | Takeda Pharmaceutical"},{"orgOrder":0,"company":"Ho Sup Lee","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase II","graph3":"Ho Sup Lee","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ho Sup Lee \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Ho Sup Lee \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"Gabrail Cancer Center Research","sponsor":"Takeda Pharmaceutical | National Cancer Institute | National Institutes of Health","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Gabrail Cancer Center Research","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Gabrail Cancer Center Research \/ Takeda Pharmaceutical | National Cancer Institute | National Institutes of Health","highestDevelopmentStatusID":"7","companyTruncated":"Gabrail Cancer Center Research \/ Takeda Pharmaceutical | National Cancer Institute | National Institutes of Health"},{"orgOrder":0,"company":"TACL Consortium","sponsor":"Takeda Pharmaceutical | Children's Hospital Los 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Pharmaceutical"},{"orgOrder":0,"company":"University of Washington","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Ixazomib Citrate","moa":"26S proteasome","graph1":"Oncology","graph2":"Phase II","graph3":"University of Washington","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Washington \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"University of Washington \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"Active Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Tasquinimod","moa":"||immunomodulators","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Active Biotech","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Active Biotech \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Active Biotech \/ Undisclosed"},{"orgOrder":0,"company":"Wistar Institute of Anatomy and Biology","sponsor":"Active Biotech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Acquisition","leadProduct":"Tasquinimod","moa":"||immunomodulators","graph1":"Oncology","graph2":"Phase I","graph3":"Wistar Institute of Anatomy and Biology","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Wistar Institute of Anatomy and Biology \/ Active Biotech","highestDevelopmentStatusID":"6","companyTruncated":"Wistar Institute of Anatomy and Biology \/ Active Biotech"}]

Find Clinical Drug Pipeline Developments & Deals for Ixazomib Citrate

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                          01

                          Wistar Institute of Anatomy and Biology

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Wistar Institute of Anatomy and Biology

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Under the terms of the agreement, Wistar grants Active Biotech a global exclusive license to develop and commercialize tasquinimod in combination therapy, as a treatment for multiple myeloma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 22, 2024

                          Lead Product(s) : Tasquinimod,Ixazomib Citrate,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Active Biotech

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Ninlaro® (ixazomib) is the first and only oral proteasome inhibitor licensed in combination with lenalidomide and dexamethasone for adults with multiple myeloma (MM).

                          Product Name : Ninlaro

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 19, 2023

                          Lead Product(s) : Ixazomib Citrate,Dexamethasone,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Ixazomib is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Multiple Myeloma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 10, 2022

                          Lead Product(s) : Ixazomib Citrate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Tasquinimod is an oral immunomodulatory and anti-angiogenic investigational treatment, that affects the tumor’s ability to grow and metastasize. Tasquinimod is developed as a new immunomodulatory treatment for multiple myeloma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 03, 2021

                          Lead Product(s) : Tasquinimod,Ixazomib Citrate,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Ninlaro (ixazomib) is an oral proteasome inhibitor, small molecule drug candidate which is being evaluated for the treatment of patients with multiple myeloma.

                          Product Name : Ninlaro

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 09, 2020

                          Lead Product(s) : Ixazomib Citrate,Dexamethasone,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Positive Phase 3 Data Evaluating NINLARO as a Maintenance Therapy (TOURMALINE-MM4) Shows Significant Improvement in Progression-Free Survival in Adult Patients Not Treated with Stem Cell Transplantation.

                          Product Name : Ninlaro

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 12, 2020

                          Lead Product(s) : Ixazomib Citrate,Dexamethasone,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : TOURMALINE-MM4, a Phase 3, randomized clinical trial evaluating the effect of single-agent oral NINLARO™ (ixazomib), an oral proteasome inhibitor used as a first-line maintenance therapy in adult patients diagnosed with multiple myeloma.

                          Product Name : Ninlaro

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 12, 2020

                          Lead Product(s) : Ixazomib Citrate,Dexamethasone,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The addition of ixazomib to lenalidomide and dexamethasone resulted in an improvement in median progression-free survival of 13.5 months; however, it did not meet the statistical significance.

                          Product Name : Ninlaro

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 10, 2020

                          Lead Product(s) : Ixazomib Citrate,Dexamethasone,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Ixazomib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Multiple Myeloma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 17, 2020

                          Lead Product(s) : Ixazomib Citrate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Omar Nadeem, MD

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Omar Nadeem, MD

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Ixazomib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Multiple Myeloma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 19, 2019

                          Lead Product(s) : Ixazomib Citrate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Takeda Pharmaceutical

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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