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    [{"orgOrder":0,"company":"Karolinska Development AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"SWEDEN","productType":"Steroid","year":"2021","type":"Inapplicable","leadProduct":"Golexanolone","moa":"GABAA receptor","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Karolinska Development AB","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Karolinska Development AB \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Karolinska Development AB \/ Inapplicable"},{"orgOrder":0,"company":"Karolinska Development AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"SWEDEN","productType":"Steroid","year":"2022","type":"Inapplicable","leadProduct":"Golexanolone","moa":"GABAA receptor","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Karolinska Development AB","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Karolinska Development AB \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Karolinska Development AB \/ Inapplicable"},{"orgOrder":0,"company":"Karolinska Development AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"SWEDEN","productType":"Steroid","year":"2022","type":"Inapplicable","leadProduct":"Golexanolone","moa":"GABAA receptor","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Karolinska Development AB","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Karolinska Development AB \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Karolinska Development AB \/ Inapplicable"}]

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                            01

                            Calliditas Therapeutics AB

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                            Calliditas Therapeutics AB

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                            Lead Product(s) : Setanaxib

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Calliditas Announces Positive TRANSFORM Phase 2b Data in Primary Biliary Cholangitis

                            Details : GKT 831 (setanaxib) is a first‐in‐class selective NOX 1/4 inhibitor. It is being evaluated for the treatment of patients with primary biliary cholangitis

                            Product Name : GKT137831

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 26, 2024

                            Lead Product(s) : Setanaxib

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Karolinska Development AB

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                            Karolinska Development AB

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                            Lead Product(s) : Golexanolone

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Karolinska Development’s Portfolio Company Umecrine Cognition Presents Positive Results From a Preclinical S...

                            Details : Study results show that treatment with Golexanolone (GR3027) for 7 days significantly reduced fatigue in test group compared to the control group (p<0.05). Further analysis shows that treatment also improved other CNS symptoms.

                            Product Name : GR3027

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            September 28, 2022

                            Lead Product(s) : Golexanolone

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Karolinska Development AB

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                            Karolinska Development AB

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                            Lead Product(s) : Golexanolone

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Karolinska Development’s Portfolio Company Umecrine Cognition Secures Funding Ahead of Phase 2 Study of Gole...

                            Details : Results from previous clinical and pre-clinical studies strongly indicate that GR3027 (golexanolone) is able to counteract such inappropriate suppression of brain activity.

                            Product Name : GR3027

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            September 14, 2022

                            Lead Product(s) : Golexanolone

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Karolinska Development AB

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                            Karolinska Development AB

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                            Lead Product(s) : Golexanolone

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Karolinska Development’s Portfolio Company Umecrine Cognition Presents New Data Supporting the Development o...

                            Details : Golexanolone, a novel drug candidate that counter acts the effect of allopregnanolone on GABAA receptors, thereby restoring normal nerve signalling in the brain.

                            Product Name : GR3027

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            March 11, 2021

                            Lead Product(s) : Golexanolone

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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