[{"orgOrder":0,"company":"Hemispherian","sponsor":"EIC fund","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Financing","leadProduct":"GLIX1","moa":"TET2","graph1":"Oncology","graph2":"Preclinical","graph3":"Hemispherian","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hemispherian \/ EIC fund","highestDevelopmentStatusID":"4","companyTruncated":"Hemispherian \/ EIC fund"},{"orgOrder":0,"company":"Hemispherian","sponsor":"Meneldor","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Series A Financing","leadProduct":"GLIX1","moa":"TET2","graph1":"Oncology","graph2":"Preclinical","graph3":"Hemispherian","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hemispherian \/ Meneldor","highestDevelopmentStatusID":"4","companyTruncated":"Hemispherian \/ Meneldor"},{"orgOrder":0,"company":"Hemispherian","sponsor":"Research Council of Norway","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Funding","leadProduct":"GLIX5","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Hemispherian","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hemispherian \/ Research Council of Norway","highestDevelopmentStatusID":"4","companyTruncated":"Hemispherian \/ Research Council of Norway"},{"orgOrder":0,"company":"Hemispherian","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2025","type":"Inapplicable","leadProduct":"GLIX1","moa":"TET2","graph1":"Oncology","graph2":"Preclinical","graph3":"Hemispherian","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hemispherian \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Hemispherian \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          CRS
                          Not Confirmed
                          CRS
                          Not Confirmed

                          Details : GLIX1 is a small molecule in preclinical studies for the treatment of glioblastoma. It is supposed to act on TET2 to increase genomic 5-hydroxymethylcytosine levels.

                          Product Name : GLIX1

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          June 06, 2025

                          Lead Product(s) : GLIX1

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          CRS
                          Not Confirmed
                          CRS
                          Not Confirmed

                          Details : The funding aims to support the Hemispherian in clinically advancing its investigational product GLIX5, a TET2 modulator, which is being evaluated in the preclinical studies for the treatment of platinum-resistant ovarian cancers.

                          Product Name : GLIX5

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 19, 2023

                          Lead Product(s) : GLIX5

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Research Council of Norway

                          Deal Size : $1.5 million

                          Deal Type : Funding

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                          03

                          CRS
                          Not Confirmed
                          CRS
                          Not Confirmed

                          Details : The proceeds will support the company's drug development activities, expand its preclinical pipeline and support preclinical development of GLIX1 and GLIX5, the company's lead assets.

                          Product Name : GLIX1

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 24, 2022

                          Lead Product(s) : GLIX1

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Meneldor

                          Deal Size : $2.9 million

                          Deal Type : Series A Financing

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                          04

                          CRS
                          Not Confirmed
                          CRS
                          Not Confirmed

                          Details : The financing will support the company's lead compound, GLIX1, is in late-stage preclinical development for the treatment of glioblastoma, a deadly cancer of the central nervous system and the leading cause of death by disease in children.

                          Product Name : GLIX1

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          October 19, 2022

                          Lead Product(s) : GLIX1

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : EIC fund

                          Deal Size : $9.9 million

                          Deal Type : Financing

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