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Health-Upstate","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2019","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Prisma Health-Upstate","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Prisma Health-Upstate \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Prisma Health-Upstate \/ Undisclosed"},{"orgOrder":0,"company":"RDD Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2011","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"RDD Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Ointment","sponsorNew":"RDD Pharma \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"RDD Pharma \/ Undisclosed"},{"orgOrder":0,"company":"RDD Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2011","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"RDD Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Suppository","sponsorNew":"RDD Pharma \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"RDD Pharma \/ Undisclosed"},{"orgOrder":0,"company":"RDD Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2010","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"RDD Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Suppository","sponsorNew":"RDD Pharma \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"RDD Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Pinnacle Biologics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2010","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Pinnacle Biologics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pinnacle Biologics \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Pinnacle Biologics \/ Undisclosed"},{"orgOrder":0,"company":"LALLEMAND HEALTH SOLUTIONS","sponsor":"ProbiSearch SL","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"CANADA","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"LALLEMAND HEALTH SOLUTIONS","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"LALLEMAND HEALTH SOLUTIONS \/ ProbiSearch SL","highestDevelopmentStatusID":"8","companyTruncated":"LALLEMAND HEALTH SOLUTIONS \/ ProbiSearch SL"},{"orgOrder":0,"company":"Stuart Wright","sponsor":"Soothing Scents, Inc.","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"","productType":"Undisclosed","year":"2016","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Stuart Wright","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Stuart Wright \/ Soothing Scents, Inc.","highestDevelopmentStatusID":"8","companyTruncated":"Stuart Wright \/ Soothing Scents, Inc."},{"orgOrder":0,"company":"OncoZenge","sponsor":"University of California","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"SWEDEN","productType":"Miscellaneous","year":"2025","type":"Collaboration","leadProduct":"Bupivacaine","moa":"Sodium channel protein type IV alpha subunit","graph1":"Gastroenterology","graph2":"Phase II","graph3":"OncoZenge","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"OncoZenge \/ University of California","highestDevelopmentStatusID":"8","companyTruncated":"OncoZenge \/ University of California"},{"orgOrder":0,"company":"Sanofi","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"FRANCE","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"SAR444336","moa":"IL-2","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Sanofi","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Sanofi \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Sanofi \/ Undisclosed"},{"orgOrder":0,"company":"Eli Lilly","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"LY3537021","moa":"Gastric inhibitory polypeptide receptor (GIPR)","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Eli Lilly","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Eli Lilly \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Eli Lilly \/ Undisclosed"},{"orgOrder":0,"company":"Catalysis - S.L.","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"SPAIN","productType":"Dietary Supplement","year":"2025","type":"Inapplicable","leadProduct":"Carminal","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Catalysis - S.L.","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Catalysis - S.L. \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Catalysis - S.L. \/ Undisclosed"}]

Find Gastroenterology Drugs in Phase II Clinical Development in UNITED STATES

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : SAR444336

                          Therapeutic Area : Gastroenterology

                          Study Phase : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : SAR444336 is a Protein drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Colitis, Microscopic.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 05, 2025

                          Lead Product(s) : SAR444336

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          Lead Product(s) : Amlitelimab

                          Therapeutic Area : Gastroenterology

                          Study Phase : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Amlitelimab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Celiac Disease.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          August 16, 2024

                          Lead Product(s) : Amlitelimab

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Details : Linaclotide is a Peptide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Constipation.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          March 08, 2023

                          Lead Product(s) : Linaclotide

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Ironwood Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          04

                          Details : Botulinum Toxin Type A is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Hernia, Ventral.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          November 07, 2022

                          Lead Product(s) : Botulinum toxin type A

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          05

                          Lead Product(s) : Ordesekimab

                          Therapeutic Area : Gastroenterology

                          Study Phase : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : PRV-015 (anti-interleukin-15) is the first investigational product to show both a reduction in gluten-induced symptoms and in markers of intestinal inflammation in a placebo-controlled trial in celiac subjects .

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          August 31, 2020

                          Lead Product(s) : Ordesekimab

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          06

                          Lead Product(s) : PRV-015

                          Therapeutic Area : Gastroenterology

                          Study Phase : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : PRV-015 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Celiac Disease.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          June 11, 2020

                          Lead Product(s) : PRV-015

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          07

                          Details : Eluxadoline is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Irritable Bowel Syndrome.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 13, 2017

                          Lead Product(s) : Eluxadoline

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          08

                          Lead Product(s) : Metronidazole

                          Therapeutic Area : Gastroenterology

                          Study Phase : Phase II

                          Sponsor : Reliance Clinical Research Services

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Metronidazole is a Plant Extract/Herbal drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Clostridium Difficile-associated Diarrhea.

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          March 21, 2012

                          Lead Product(s) : Metronidazole

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Reliance Clinical Research Services

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          09

                          Details : Eluxadoline is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Irritable Bowel Syndrome.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 25, 2010

                          Lead Product(s) : Eluxadoline

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The partnership focuses on a patient engagement study in managing oral mucositis pain, while exploring potential pathways toward a future IND application for BupiZenge.

                          Product Name : BupiZenge

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          September 17, 2025

                          Lead Product(s) : Bupivacaine

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : University of California

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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