[{"orgOrder":0,"company":"Eli Lilly","sponsor":"Pfizer Inc","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Cetuximab","moa":"||Epidermal growth factor receptor erbB1","graph1":"Oncology","graph2":"Approved FDF","graph3":"Eli Lilly","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Eli Lilly \/ Pfizer Inc","highestDevelopmentStatusID":"15","companyTruncated":"Eli Lilly \/ Pfizer Inc"},{"orgOrder":0,"company":"Erasca","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Cetuximab","moa":"||ERK1\/2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Erasca","amount2":0,"highestDevelopmentShortName":"Ph 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                          01

                          SRH Wald-Klinikum Gera

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                          FNCE
                          Not Confirmed

                          SRH Wald-Klinikum Gera

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                          FNCE
                          Not Confirmed

                          Details : Encorafenib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Melanoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 29, 2025

                          Lead Product(s) : Encorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Pierre Fabre

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Grupo Español Multidisciplinar de Melanoma

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                          FNCE
                          Not Confirmed

                          Grupo Español Multidisciplinar de Melanoma

                          Country arrow
                          FNCE
                          Not Confirmed

                          Details : Encorafenib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Melanoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 20, 2025

                          Lead Product(s) : Encorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Regeneron Pharmaceuticals | MFAR | Pierre Fabre

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Braftovi (encorafenib) is a BRAF V600E inhibitor, currently being investigated in combination with cetuximab and mFOLFOX6 in patients with mCRC with a BRAF V600E mutation.

                          Product Name : Braftovi

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 03, 2025

                          Lead Product(s) : Encorafenib,Fluorouracil,Cetuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Braftovi (encorafenib) is a BRAF V600E inhibitor, currently being investigated in combination with cetuximab and mFOLFOX6 in patients with mCRC with a BRAF V600E mutation.

                          Product Name : Braftovi

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 27, 2025

                          Lead Product(s) : Encorafenib,Fluorouracil,Cetuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Braftovi (encorafenib) in combination with cetuximab is approved for the treatment of adult patients with BRAFV600-mutant advanced colorectal cancer.

                          Product Name : Braftovi

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 20, 2024

                          Lead Product(s) : Encorafenib,Cetuximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Fondazione Policlinico Universitario Agostino Gemelli

                          Country arrow
                          FNCE
                          Not Confirmed

                          Fondazione Policlinico Universitario Agostino Gemelli

                          Country arrow
                          FNCE
                          Not Confirmed

                          Details : Encorafenib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 15, 2024

                          Lead Product(s) : Encorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Pierre Fabre

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Spanish Cooperative Group for Digestive Tumours

                          Country arrow
                          FNCE
                          Not Confirmed

                          Spanish Cooperative Group for Digestive Tumours

                          Country arrow
                          FNCE
                          Not Confirmed

                          Details : Encorafenib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 17, 2024

                          Lead Product(s) : Encorafenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Merck Group | Pierre Fabre

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : The companies will work to seek the regulatory approval for Foundation Medicine assays which detect mutations including BRAFV600E to identify patients for potential treatment with Pierre’s BRAF/MEK inhibitor, BRAFTOVI (encorafenib) and MEKTOVI (binimet...

                          Product Name : Braftovi

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          November 15, 2023

                          Lead Product(s) : Encorafenib,Binimetinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Pierre Fabre

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          09

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Braftovi (encorafenib) + Mektovi (binimetinib) is approved for the treatment of adult patients with BRAFV600-mutant advanced non-small cell lung cancer (NSCLC), who are either treatment naïve or have received prior therapy.

                          Product Name : Braftovi

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 02, 2023

                          Lead Product(s) : Encorafenib,Binimetinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Braftovi (Encorafenib) is an oral small molecule BRAF kinase inhibitor and is approved in combination with Mektovi (binimetinib) in patients with BRAF V600E-mutant metastatic non-small cell lung cancer.

                          Product Name : Braftovi

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 12, 2023

                          Lead Product(s) : Encorafenib,Binimetinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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