
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : EGEN-2784
Therapeutic Area : Nephrology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
eGenesis Gets IND Clearance for EGEN-2784 in Kidney Transplant Study
Details : EGEN-2784 is a genetically engineered porcine-derived kidney, in patients with end stage kidney disease (ESKD).
Product Name : EGEN-2784
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
September 08, 2025
Lead Product(s) : EGEN-2784
Therapeutic Area : Nephrology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Eledon Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : AT-1501 (tegoprubart) is an investigational, humanized IgG1 anti-CD40L antibody with high affinity for the CD40 ligand. CD40L plays a pivotal role in immune system activation by mediating both antibody and cellular immune responses.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Eledon Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : HuCo Islet Cell
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : University of Miami
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration will encompass the evaluation of gene-edited pancreatic HuCo™ islet cells in a clinically relevant diabetes model as a prerequisite to advancing to human clinical trials.
Product Name : HuCo Islet Cells
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
March 09, 2022
Lead Product(s) : HuCo Islet Cell
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : University of Miami
Deal Size : Undisclosed
Deal Type : Collaboration
