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Oncology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Onvansertib","moa":"||Serine\/threonine-protein kinase PLK1","graph1":"Oncology","graph2":"Phase II","graph3":"Cardiff Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cardiff Oncology \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Cardiff Oncology \/ Undisclosed"},{"orgOrder":0,"company":"Trovagene","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Onvansertib","moa":"||Serine\/threonine-protein kinase PLK1","graph1":"Oncology","graph2":"Phase II","graph3":"Trovagene","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Trovagene \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Trovagene \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals for DSSTox_CID_28969

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                          01

                          Lead Product(s) : Abiraterone Acetate,Prednisolone

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Abiraterone and the combination product Abiraterone/Prednisolone are used to treat men with prostate cancer. The 500 mg (mono product) and 500 mg + 5 mg (combination product) tablets will be marketed in Europe by our partners.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 17, 2022

                          Lead Product(s) : Abiraterone Acetate,Prednisolone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Tiefenbacher Compnay Banner

                          02

                          Lead Product(s) : Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Abiraterone Acetate Tablets USP, 250 mg, a therapeutic equivalent generic version of Zytiga® (abiraterone acetate), is an anticancer medication. It works by preventing androgen (male hormone) production in man.

                          Product Name : Abiraterone Acetate-Generic

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 19, 2020

                          Lead Product(s) : Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : ORIC intends to use the net proceeds to fund research and development of its clinical-stage product candidates, including ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 28, 2025

                          Lead Product(s) : ORIC-944,Abiraterone Acetate,Apalutamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : SR One

                          Deal Size : $125.0 million

                          Deal Type : Private Placement

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The proceeds will support advancement of the company’s clinical-stage pipeline, which includes FT-7051 (pocenbrodib) is being evaluated for metastatic castration-resistant prostate cancer.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          May 15, 2025

                          Lead Product(s) : Pocenbrodib,Abiraterone Acetate,Olaparib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : $365.0 million

                          Deal Type : Series D Financing

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : FT-7051 (pocenbrodib) is a CBP/p300 inhibitor, is being investigated as alone and in combination with abiraterone acetate, in patients with mCRPC.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 20, 2025

                          Lead Product(s) : Pocenbrodib,Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : TLX591 (177Lu-DOTA-TLX591) is first-in-class radio-ADC investigational therapy, which is investigated for the the treatment of PSMA positive metastatic castration-resistant prostate cancer.

                          Product Name : Undisclosed

                          Product Type : Radiolabeled Compound

                          Upfront Cash : Inapplicable

                          February 25, 2025

                          Lead Product(s) : 177-Lu Rosopatamab Tetraxetan,Abiraterone Acetate,Enzalutamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor, is being investigated for PTEN-deficient de novo mHSPC in combination with abiraterone and ADT.

                          Product Name : Truqap

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 25, 2024

                          Lead Product(s) : Capivasertib,Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Gabrail Cancer Center Research

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Gabrail Cancer Center Research

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Pfizer Inc | Sumitomo Pharma America | National Comprehensive Cancer Network | National Cancer Institute

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Abiraterone Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Prostatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 21, 2024

                          Lead Product(s) : Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Pfizer Inc | Sumitomo Pharma America | National Comprehensive Cancer Network | National Cancer Institute

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Canadian Cancer Trials Group

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Canadian Cancer Trials Group

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : ECOG-ACRIN Cancer Research Group | NRG Oncology | Alliance for Clinical Trials in Oncology | SWOG Cancer Research Network

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Abiraterone is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Prostatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 19, 2024

                          Lead Product(s) : Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : ECOG-ACRIN Cancer Research Group | NRG Oncology | Alliance for Clinical Trials in Oncology | SWOG Cancer Research Network

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Lynparza (olaparib) in combination with abiraterone and prednisone or prednisolone indicated for the treatment of adult patients with BRCA-mutated metastatic castration-resistant prostate cancer.

                          Product Name : Lynparza

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 03, 2024

                          Lead Product(s) : Olaparib,Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Foundation Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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