
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Delcath Gains FDA IND Clearance for HEPZATO Trial in Breast Cancer Liver Mets
Details : Hepzato (melphalan HCl) in combination with standard of care (SOC) is being investigated for liver-dominant metastatic breast cancer (mBC).
Product Name : Hepzato
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
April 28, 2025
Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : Melphalan is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Breast Neoplasms.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
March 13, 2025

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Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : $16.3 million
Deal Type : Series E Financing
Delcath Gains $16.3M Funding Through Series E Warrant Exercises
Details : The financing aims to advance the late-stage clinical trial studies of Hepzato (melphalan), which is being evaluated for the treatment of uveal melanoma.
Product Name : Hepzato
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
December 30, 2024
Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : $16.3 million
Deal Type : Series E Financing

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Lead Product(s) : Melphalan Hydrochloride,Tipiracil Hydrochloride,Trifluridine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Delcath Gets FDA IND Clearance for Phase 2 Trial Of HEPZATO™ in Liver Cancer
Details : Hepzato kit is a drug/device product which administers melphalan directly to the liver through the HDS, being investigated in combination with trifluridine-tipiracil for metastatic colorectal cancer.
Product Name : Hepzato
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
December 02, 2024
Lead Product(s) : Melphalan Hydrochloride,Tipiracil Hydrochloride,Trifluridine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : Melphalan is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Colorectal Neoplasms.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
September 23, 2024

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Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aelyrin Announces 32-Week Data from Phase 2b of Izokibep in Hidradenitis Suppurativa
Details : Hepzato kit (melphalan) is a combination drug/device product which administers melphalan directly to the liver through the HDS. It is approved for the treatment of metastatic uveal melanoma (mUM).
Product Name : Hepzato
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
January 16, 2024
Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Delcath Announces Poster Presentation at the 2022 ASCO Annual Meeting
Details : Alkeran (melphalan), is designed to administer high-dose chemotherapy to the liver while minimizing systemic exposure and associated side effects via filtration of the chemotherapeutic agent from the blood.
Product Name : Hepzato
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
May 09, 2022
Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The event will feature, updated Focus trial data and the role of Hepzato™ Kit (melphalan hydrochloride for injection/Hepatic Delivery System) as a potential treatment for patients with hepatic-dominant metastatic ocular melanoma.
Product Name : Hepzato
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
November 05, 2021
Lead Product(s) : Melphalan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : Melphalan is a Cytotoxic Drug drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Uveal Melanoma.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
August 26, 2021

Delcath Systems Prices $22M Public Offering
Details : Delcath intends to use the net proceeds of the offering for working capital and general corporate purposes including the continued development of Melphalan/HDS.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
May 01, 2020
