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[{"orgOrder":0,"company":"McGill University","sponsor":"Clarus","pharmaFlowCategory":"D","amount":"$40.8 million","upfrontCash":"$0.4 million","newsHeadline":"Clarus Therapeutics and McGill University Announce Exclusive Worldwide Licensing Agreement To Develop and Commercialize Technology To Treat Rare Conditions Associated With Coenzyme-Q10 (Ubiquinone) Deficiencies","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Discovery","country":"","productType":"Small molecule","productStatus":"Approved","date":"September 2021","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Discovery"},{"orgOrder":0,"company":"Scynexis","sponsor":"GSK","pharmaFlowCategory":"D","amount":"$593.0 million","upfrontCash":"$90.0 million","newsHeadline":"SCYNEXIS Announces Achievement of First Development Milestone of $25 Million Under Exclusive License Agreement with GSK","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"June 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III"},{"orgOrder":0,"company":"Scynexis","sponsor":"GSK","pharmaFlowCategory":"D","amount":"$401.0 million","upfrontCash":"$90.0 million","newsHeadline":"GSK Amends Deal with Scynexis Amid Brexafemme Manufacturing Woes","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"January 2024","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III"}]

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            Details:

            Under the agreement, GSK has the rights to develop GSK5458448/SCY-078 (ibrexafungerp), a novel oral glucan synthase inhibitor with a broad spectrum of activity and commercialize Brexafemme (ibrexafungerp tablets) in all countries except the greater China region.

            Lead Product(s): Ibrexafungerp Citrate,Caspofungin

            Therapeutic Area: Infections and Infectious Diseases Product Name: GSK5458448

            Highest Development Status: Phase III Product Type: Small molecule

            Partner/Sponsor/Collaborator: GSK

            Deal Size: $401.0 million Upfront Cash: $90.0 million

            Deal Type: Licensing Agreement January 03, 2024

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            Under the agreement GSK gains right to commercialize Brexafemme (ibrexafungerp), a novel glucan synthase inhibitor, for vulvovaginal candidiasis and RVVC while continuing to develop ibrexafungerp, in phase 3 trials for the potential treatment of invasive candidiasis.

            Lead Product(s): Ibrexafungerp Citrate,Caspofungin

            Therapeutic Area: Infections and Infectious Diseases Product Name: Brexafemme

            Highest Development Status: Phase III Product Type: Small molecule

            Partner/Sponsor/Collaborator: GSK

            Deal Size: $593.0 million Upfront Cash: $90.0 million

            Deal Type: Licensing Agreement June 21, 2023

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            McGill University

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            Under the licensing agreement Clarus will develop and commercialize McGill’s proprietary technology designed to treat conditions associated with CoQ10 deficiencies in humans with Coenzyme-Q10 (Ubiquinone).

            Lead Product(s): Coenzyme Q10,Caspofungin

            Therapeutic Area: Genetic Disease Product Name: Ubiquinone

            Highest Development Status: Discovery Product Type: Small molecule

            Partner/Sponsor/Collaborator: Clarus

            Deal Size: $40.8 million Upfront Cash: $0.4 million

            Deal Type: Licensing Agreement September 16, 2021

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