Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
aTyr’s Efzofitimod Passes Fourth Positive DSMB Review in Phase 3
Details : ATYR1923 (efzofitimod) is a tRNA synthetase-derived therapy based on a naturally occurring, lung-enriched, splice variant of HARS. It is being evaluated for pulmonary sarcoidosis.
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
March 06, 2025
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
aTyr Pharma Announces Third Positive DSMB Review for Efzofitimod in Ph 3 EFZO-FIT™ Study
Details : ATYR1923 (efzofitimod) is a tRNA synthetase-derived therapy based on a naturally occurring, lung-enriched, splice variant of HARS. It is being evaluated for pulmonary sarcoidosis.
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
aTyr Pharma Completes Phase 3 Enrollment for EFZO-FIT™ Study in Pulmonary Sarcoidosis
Details : ATYR1923 (efzofitimod) is a tRNA synthetase-derived therapy based on a naturally occurring, lung-enriched, splice variant of HARS. It is being evaluated for pulmonary sarcoidosis.
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
July 22, 2024
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
aTyr Reports Second Positive DSMB Review For Efzofitimod In Sarcoidosis Trial
Details : ATYR1923 (efzofitimod) is a tRNA synthetase-derived therapy based on a naturally occurring, lung-enriched, splice variant of HARS. It is being evaluated for pulmonary sarcoidosis.
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
May 14, 2024
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
aTyr Announces Expanded Access Program for EFZO-FIT™ Trial Participants
Details : ATYR1923 (efzofitimod), a tRNA synthetase-derived therapy, is being evaluated for pulmonary sarcoidosis, targeting a lung-enriched splice variant of HARS.
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
February 21, 2024
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Efzofitimod is a first-in-class biologic immunomodulator, under phase 2 clinical trials for systemic sclerosis-related interstitial lung disease. It selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve inflammation without...
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
October 31, 2023
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : RBC Capital Markets
Deal Size : $15.0 million
Deal Type : Public Offering
aTyr Pharma Announces Pricing of Public Offering of Common Stock
Details : aTyr intends to use the net proceeds for general corporate purposes, including the ongoing development of ATYR1923 (efzofitimod) and the expansion of its clinical development program to include a planned Phase 2 study of efzofitimod in patients with syst...
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Undisclosed
September 02, 2023
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : RBC Capital Markets
Deal Size : $15.0 million
Deal Type : Public Offering
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATYR1923 (efzofitimod) is a potential first-in-class, works by selectively modulating Neuropilin-2 (NRP2) to downregulate the innate and adaptive immune responses in uncontrolled inflammatory disease states to resolve inflammation and prevent subsequent ...
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
January 31, 2023
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod,Pirfenidone
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATYR1923 (efzofitimod) is a potential first-in-class, works by selectively modulating Neuropilin-2 (NRP2) to downregulate the innate and adaptive immune responses in uncontrolled inflammatory disease states to resolve inflammation and prevent subsequent ...
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
January 19, 2023
Lead Product(s) : Efzofitimod,Pirfenidone
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATYR1923 (efzofitimod), a fusion protein comprised of the immunomodulatory domain of histidyl-tRNA synthetase fused to the FC region of a human antibody, is a selective modulator of neuropilin-2 that downregulates innate and adaptive immune response in i...
Product Name : ATYR1923
Product Type : Protein
Upfront Cash : Inapplicable
January 18, 2023
Lead Product(s) : Efzofitimod
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable