
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

FDA grants fast track designation to AskBio’s AB-1005 for PD
Details : AB-1005 is an investigational gene therapy based on AAV2 containing the GDNF transgene. It is under phase 1 clinical development for the treatment of Parkinson's disease.
Product Name : AB-1005
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
December 07, 2024

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Lead Product(s) : AB-1005
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AskBio Begins Patient Recruitment for AB-1005 in Phase 2 Parkinson’s Trial
Details : AB-1005 is an investigational gene therapy based on AAV2 containing the GDNF transgene. It is under phase 1 clinical development for the treatment of Parkinson's disease.
Product Name : AB-1005
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 27, 2024
Lead Product(s) : AB-1005
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : NAN-101
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Bayer AG
Deal Size : Inapplicable
Deal Type : Inapplicable
AskBio Gets FDA Fast Track Designation for AB-1002 Gene Therapy Program in Heart Failure
Details : NAN-101 (AB-1002) is a gene therapy under investigation, currently undergoing phase 2 clinical trials for the treatment of congestive heart failure.
Product Name : NAN-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 18, 2024
Lead Product(s) : NAN-101
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Bayer AG
Deal Size : Inapplicable
Deal Type : Inapplicable

Askbio Presents 18-Month Phase Ib Trial Results of AB-1005 Gene Therapy for Parkinson’s
Details : AB-1005 (AAV2-GDNF) is an investigational gene therapy based on AAV2 containing the human glial cell line-derived neurotrophic factor (GDNF) transgene, being investigated for Parkinson’s disease.
Product Name : AB-1005
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 16, 2024

AskBio Phase Ib Trial Of Ab-1005 Gene Therapy in Parkinson’s Disease Meets Endpoint
Details : AB-1005 is an investigational gene therapy based on AAV2 containing the human GDNF transgene. It is under Phase 1 clinical development for treating Parkinson's disease.
Product Name : AB-1005
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 01, 2024

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Lead Product(s) : NAN-101
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Bayer AG
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patient Randomized in AskBio Phase II Gene Therapy Trial for Heart Failure
Details : AB-1002 (NAN-101) is an investigational gene therapy, which is currently under phase 2 clinical development for the treatment of congestive heart failure.
Product Name : NAN-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 16, 2024
Lead Product(s) : NAN-101
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Bayer AG
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AB-1005
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AskBio announces First Patient Randomized in Phase 1 Trial of AB-1005
Details : AB-1005 is an investigational gene therapy based on adeno-associated viral vector serotype 2 (AAV2) containing the human glial cell line-derived neurotrophic factor (GDNF) transgene. It is under phase 1 clinical development for the treatment of Parkinson...
Product Name : AB-1005
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
November 17, 2023
Lead Product(s) : AB-1005
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : ReCode Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : AskBio will combine its synthetic DNA and gene editing nucleases with ReCode's selective organ targeting LNP technology to potentially create an all-in-one solution that enables full gene insertion by delivering with precision both the gene editing tool ...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 01, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : ReCode Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

Details : AB-1005 is an adeno-associated virus 2 (AAV2) glial cell line-derived neurotrophic factor (GDNF) gene therapy for the treatment of mild to moderate parkinson’s disease.
Product Name : AB-1005
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
March 29, 2023

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Lead Product(s) : AB-1003
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AB-1003 (also known as LION-101) is a novel investigational recombinant adeno-associated virus based gene therapy currently being developed as a one-time intravenous infusion for the treatment of patients with LGMD type 2I/R9.
Product Name : AB-1003
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
March 08, 2023
Lead Product(s) : AB-1003
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
