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Through the acquisition, SERB has acquired exclusive US rights to the ticagrelor reversal agent PB2452 (bentracimab), a novel, monoclonal antibody fragment, from SFJ. SFJ will remain responsible for the ongoing trials of bentracimab and will work with SERB to submit the BLA.


Lead Product(s): Bentracimab

Therapeutic Area: Hematology Product Name: PB2452

Highest Development Status: Phase IIIProduct Type: Large molecule

Recipient: SFJ Pharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition May 11, 2023

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Company recieved positive opinion of CHMP of Voraxaze® (glucarpidase) based on clinical data and real world experience. Voraxaze reduces toxic plasma methotrexate concentration in adults and children may quickly lower MTX levels and avoid further systemic damage.


Lead Product(s): Glucarpidase

Therapeutic Area: Pharmacology/Toxicology Product Name: Voraxaze

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: BTG Specialty Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 25, 2021

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BTG Specialty Pharmaceuticals has a portfolio of market-leading emergency care products, including CroFab®, Voraxaze®, and DigiFab®.


Lead Product(s): Glucarpidase

Therapeutic Area: Pharmacology/Toxicology Product Name: Voraxaze

Highest Development Status: ApprovedProduct Type: Large molecule

Recipient: BTG Specialty Pharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition March 02, 2021

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