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    01 API Development (3)

    02 Analytical Method Development (1)

    03 Capsule (1)

    04 Clinical Supply (1)

    05 Contract Manufacturing (1)

    06 Contract Services (7)

    07 Controlled Substance (1)

    08 Cream / Lotion / Ointment (1)

    09 Cytotoxic Compound (1)

    10 Fine Chemical / Intermediate (1)

    11 GMP Manufacturing (1)

    12 Gel (1)

    13 High Potency APIs (HPAPIs) (1)

    14 Micronization (1)

    15 Process Development & Optimization (1)

    16 Steroid / Hormone (1)

    17 Tablet (1)

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    Fermion Oy

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    CMO FOR HORMONAL GELS & SOLUTIONS

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    Fermion, through its mother company Orion, offers contract manufacturing services for hormonal and non-hormonal semi-solids, including gels, creams, ointments and solutions with potent OEB4-5 APIs.

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    Pharma Service: Drug Product Manufacturing

    Category: Gel

    Sub Category: Overview

    CMO for Hormonal Gels & Solutions

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    API MICRONIZATION SERVICES

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    Fermion has a manufacturing module for separate final handling with a micronization area which is equipped with small-scale mills designed for APIs used in dry powder inhaler drug delivery systems. It is capable of handling OEB5 classified APIs.

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    Pharma Service: API Manufacturing

    Category: Micronization

    Sub Category: Overview

    API Micronization Services

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    CONTRACT MANUFACTURING FOR CYTOTOXIC APIs

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    Fermion is a contract development and manufacturing organization (CDMO) with two USFDA and EMA approved API manufacturing sites for the commercial manufacturing of cytotoxic APIs, steroids and conventional molecules.

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    Pharma Service: API Manufacturing

    Category: Cytotoxic Compound

    Sub Category: Overview

    Contract Manufacturing for Cytotoxic APIs

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    CONTROLLED SUBSTANCE API MANUFACTURING

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    Fermion is an API CDMO with dedicated resources for manufacturing class IV narcotics and large-scale immunosuppressants with a reactor capacity of 25 m3 for OEB5 (0.1 – 1 µg/m3) classified APIs at its Hanko site.

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    Pharma Service: API Manufacturing

    Category: Controlled Substance

    Sub Category: Overview

    Controlled Substance Manufacturing

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    CLINICAL SUPPLY OF APIs

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    Fermion’s API contract services cover the needs of customers from the clinical phase I stage until commercial production with extensive experience in NCE (new chemical entity) drug substance development and manufacturing.

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    Pharma Service: API Manufacturing

    Category: Clinical Supply

    Sub Category: Overview

    Clinical Supply of APIs

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    SERIALIZATION & AGGREGATION CAPABILITIES

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    Fermion, through its mother company Orion, provides single-dose sachet filling, bottle filling and packaging services. Two bottle filling lines are integrated with secondary packaging lines, along with serialization and aggregation capabilities.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Serialization Compliance

    Serialization & Aggregation Capabilities

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    BLISTER PACKAGING SERVICES

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    Fermion, through its mother company Orion, has a packaging and logistics center with three blister lines and four bottle lines and over 42 million blister packs and bottles.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Blister

    Blister Packaging Services

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    BOTTLE PACKAGING SERVICES

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    Fermion, through its mother company Orion, handles the packaging and dispatching of over 42 million bottles and blister packs annually from its four bottle filling lines and three blister lines integrated with secondary packaging lines.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Bottle

    Bottle Packaging Services

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    JAR PACKAGING

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    Fermion, through its mother company Orion, has expertise in manufacturing tablets which are pressed with WIP-tablet press and packed into jars in a containment chamber. The products can be packed in plastic jars and serialized when needed.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Jar

    Jar Packaging

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    CONTRACT PACKAGING SERVICES

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    Fermion, through its mother company Orion, offers stand-alone contract packaging with one major packaging & logistics center at Orion’s site in Salo. However, some departments may also have packaging operations integrated to the bulk production line.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Overview

    Contract Packaging Services

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    SACHET FILLING & PACKAGING SERVICES

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    Fermion, through its mother company Orion, has one single-dose sachet filling and packaging line. Two bottle filling lines are integrated with secondary packaging lines with serialization and aggregation capabilities.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Pouch / Sachet / Stick Pack

    Sachet Filling & Packaging Services

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    SECONDARY PACKAGING SERVICES

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    Fermion, through its mother company Orion, provides bottle filling services integrated with secondary packaging, including serialization and aggregation.

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    Pharma Service: Packaging

    Category: Contract Services

    Sub Category: Secondary Packaging

    Secondary Packaging Services

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    DEVELOPMENT OF HIGHLY POTENT APIs

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    Fermion's R&D laboratory contains 55 fume hoods & has special laboratory spaces for hydrogenation & highly potent APIs (HPAPI). Fermion’s Oulu site focuses on smaller volume highly potent OEB5 APIs from a scale of 1-2kg per batch to one metric ton.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: High Potency APIs (HPAPIs)

    Development of Highly Potent APIs

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    DRUG SUBSTANCE DEVELOPMENT SERVICES

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    Fermion's contract development and manufacturing services cover the needs of customers from the clinical phase I stage until commercialization. It has extensive experience in NCE drug substance development and production since the 1990s.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Overview

    Drug Substance Development Services

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    API SCALE-UP CAPABILITIES

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    Fermion’s bench scale unit (kilo scale laboratory) is fully automated & equipped with high containment processing technology. It has the capability to commercially manufacture highly potent OEB5 APIs from a scale of 1-2 kg per batch to one metric ton.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Scale-Up Capabilities

    API Scale-Up Capabilities

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    MANUFACTURING OF POTENT & CYTOTOXIC TABLETS

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    Established in 1982, Orion has acquired long-term expertise in manufacturing highly potent & high-quality cytotoxics. The focus areas of its drug product contract manufacturing services include cytotoxic oral solids, such as tablets and capsules.

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    Pharma Service: Drug Product Manufacturing

    Category: Tablet

    Sub Category: High Potency APIs (HPAPIs)

    Manufacturing of Potent & Cytotoxic Tablets

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    API CONTRACT MANUFACTURING SERVICES

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    Fermion offers contract manufacturing services for drug substances with an API product portfolio consisting of over 30 generic APIs and over 10 NCEs. It also has the capability to produce highly potent compounds (HPAPIs).

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    Pharma Service: API Manufacturing

    Category: Contract Manufacturing

    Sub Category: Overview

    API Contract Manufacturing Services

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    API PROCESS DEVELOPMENT

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    Fermion’s API contract development and manufacturing services include process development and custom synthesis with route suitability and impurity control (organic, mutagenic) for active pharmaceutical ingredients (APIs).

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    Pharma Service: API Manufacturing

    Category: Process Development & Optimization

    Sub Category: Overview

    API Process Development

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    ANALYTICAL METHOD DEVELOPMENT & VALIDATION

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    Fermion offers the development of analytical methods for SMs, IMs & APIs for Phase I, II & III together with the validation of API analytical methods.

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    Pharma Service: Analytical

    Category: Analytical Method Development

    Sub Category: Method Development and Validation

    Analytical Method Development & Validation

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    CYTOTOXIC CAPSULE MANUFACTURING SERVICES

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    Fermion, through its mother company Orion, offers contract manufacturing services for capsules and tablets with expertise in highly potent, high-quality cytotoxics manufacturing.

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    Pharma Service: Drug Product Manufacturing

    Category: Capsule

    Sub Category: High Potency APIs (HPAPIs)

    Cytotoxic Capsule Manufacturing Services

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    HORMONAL & NON-HORMONAL CREAMS & OINTMENTS

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    Fermion, through its mother company Orion, offers contract manufacturing services for hormonal and non-hormonal semi-solid dosage forms, including creams, ointments, and gels, along with liquids such as solutions and suspensions with potent OEB4-5 APIs.

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    Pharma Service: Drug Product Manufacturing

    Category: Cream / Lotion / Ointment

    Sub Category: Overview

    Hormonal & Non-Hormonal Creams & Ointments

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    HPAPI CONTRACT MANUFACTURING SERVICES

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    Fermion is a CDMO with manufacturing expertise in highly potent APIs, high-quality cytotoxics with three fully automated HPAPI modules for OEB5 (0,1 - 1 µg/m3) classified APIs with reactors of 250 L, 400 L and 600 L.

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    Pharma Service: API Manufacturing

    Category: High Potency APIs (HPAPIs)

    Sub Category: Overview

    HPAPI Contract Manufacturing Services

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    CDMO FOR INTERMEDIATES & APIs

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    Fermion is a contract development and manufacturing organization (CDMO) comprising of three manufacturing units for intermediates and APIs along with distillery, hydrogenation, maintenance, warehouses, QC laboratory, and administrative functions.

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    Pharma Service: API Manufacturing

    Category: Fine Chemical / Intermediate

    Sub Category: Overview

    CDMO for Intermediates & APIs

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    GMP MANUFACTURING FOR APIs

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    Fermion is a CDMO which has a bench scale unit fully automated and equipped with high containment processing technology. The unit manufactures APIs as per cGMP guidelines and has technical capabilities that include 10-30 L reactors.

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    Pharma Service: API Manufacturing

    Category: GMP Manufacturing

    Sub Category: Overview

    GMP Manufacturing for APIs

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    STEROID API MANUFACTURING

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    Fermion is a contract development and manufacturing organization (CDMO) with two USFDA and EMA approved API manufacturing sites for the commercial manufacturing of steroids, cytotoxic APIs and conventional molecules.

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    Pharma Service: API Manufacturing

    Category: Steroid / Hormone

    Sub Category: Overview

    Steroid API Manufacturing

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