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Corporation","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Orion Corporation \/ Marinus Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Orion Corporation \/ Marinus Pharmaceuticals"},{"orgOrder":0,"company":"Orion Corporation","sponsor":"Marinus Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Collaboration","leadProduct":"Ganaxolone","moa":"GABA-A receptor; anion channel","graph1":"Rare Diseases and Disorders","graph2":"Approved FDF","graph3":"Orion Corporation","amount2":0.14999999999999999,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Rare Diseases","amount2New":0.14999999999999999,"dosageForm":"Suspension","sponsorNew":"Orion Corporation \/ Orion Corporation","highestDevelopmentStatusID":"15","companyTruncated":"Orion Corporation \/ Orion Corporation"},{"orgOrder":0,"company":"Orion Corporation","sponsor":"LegoChem Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SOUTH KOREA","productType":"Antibody-drug Conjugate","year":"2024","type":"Financing","leadProduct":"IKS014","moa":"HER2","graph1":"Oncology","graph2":"Phase III","graph3":"Orion Corporation","amount2":0.40999999999999998,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.40999999999999998,"dosageForm":"Infusion","sponsorNew":"Orion Corporation \/ Orion Corporation","highestDevelopmentStatusID":"10","companyTruncated":"Orion Corporation \/ Orion Corporation"},{"orgOrder":0,"company":"Orion Corporation","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"FINLAND","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Tiotropium Bromide","moa":"Muscarinic acetylcholine receptor 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Corporation"},{"orgOrder":0,"company":"Orion Corporation","sponsor":"Orion Corporation","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"FRANCE","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Levosimendan","moa":"Troponin, cardiac muscle | Phosphodiesterase 3","graph1":"Neurology","graph2":"Phase II","graph3":"Orion Corporation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Orion Corporation \/ Orion Corporation","highestDevelopmentStatusID":"8","companyTruncated":"Orion Corporation \/ Orion Corporation"},{"orgOrder":0,"company":"Orion Corporation","sponsor":"Tenax Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"FINLAND","productType":"Miscellaneous","year":"2020","type":"Licensing Agreement","leadProduct":"Levosimendan","moa":"Troponin, cardiac muscle | Phosphodiesterase 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Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Orion Corporation","amount2":0.79000000000000004,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0.79000000000000004,"dosageForm":"Undisclosed","sponsorNew":"Orion Corporation \/ Orion Corporation","highestDevelopmentStatusID":"2","companyTruncated":"Orion Corporation \/ Orion Corporation"}]

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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : FZ008-145

                          Therapeutic Area : Neurology

                          Study Phase : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : FZ008-145 is a highly selective second-generation Nav1.8 inhibitor, offering powerful, non-addictive pain relief advantages. It is being evaluated in preclinical studies for acute and chronic pain.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 10, 2024

                          Lead Product(s) : FZ008-145

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          fermion

                          02

                          Lead Product(s) : Trilaciclib,Irinotecan HCl Trihydrate,Oxaliplatin

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : G1 Therapeutics, Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The FDA approved COSELA™ (trilaciclib) as the first and only myeloprotection therapy to decrease the incidence of chemotherapy-induced myelosuppression.

                          Product Name : Cosela

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 12, 2021

                          Lead Product(s) : Trilaciclib,Irinotecan HCl Trihydrate,Oxaliplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : G1 Therapeutics, Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          fermion

                          03

                          Details : Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated for the treatment of metastatic hormone-sensitive prostate cancer.

                          Product Name : Nubeqa

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          June 03, 2025

                          Lead Product(s) : Darolutamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Fermion Orion Company Banner

                          04

                          Details : Orion will gain exclusive right to distribute, market and sell Shilpa’s sRbumin, a recombinant human albumin in Europe.

                          Product Name : sRbumin

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          May 23, 2025

                          Lead Product(s) : Recombinant Human Albumin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase I

                          Recipient : Shilpa Medicare

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Fermion Orion Company Banner

                          05

                          Details : Tasipimidine is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Sleep Initiation and Maintenance Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 04, 2025

                          Lead Product(s) : Tasipimidine

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase II

                          Sponsor : Icon Plc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Fermion Orion Company Banner

                          06

                          Details : Under the licensing agreement, Orion will hold the exclusive rights of the Aporon(apomorphine HCl), which is being evaluated for the treatment of OFF episodes in patients with Parkinson’s disease.

                          Product Name : Aporon

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          April 25, 2025

                          Lead Product(s) : Apomorphine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Recipient : Criceto Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Fermion Orion Company Banner

                          07

                          Details : Under the terms of the agreements, Invenra will leverage its B-Body bispecific antibody platform from monoclonal antibody discovery to treat cancer.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 30, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Sponsor : Invenra

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Fermion Orion Company Banner

                          08

                          Details : Nubeqa (darolutamide) is an orally available androgen receptor inhibitors, which is currently being evaluated for the treatment of metastatic hormone-sensitive prostate cancer.

                          Product Name : Nubeqa

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          January 07, 2025

                          Lead Product(s) : Darolutamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Bayer AG

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Fermion Orion Company Banner

                          09

                          Details : under the termination agreement, Marinus regains Ztalmy (ganaxolone) rights in Europe. It is approved for the adjunctive treatment of epileptic seizures associated with CDKL5 deficiency disorder.

                          Product Name : Ztalmy

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          December 30, 2024

                          Lead Product(s) : Ganaxolone

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Marinus Pharmaceuticals

                          Deal Size : $1.5 million

                          Deal Type : Termination

                          Fermion Orion Company Banner

                          10

                          Details : The collaboration combines Abilita's strength in discovering breakthrough antibody therapeutics for challenging membrane protein targets with Orion's proven expertise in oncology, pain.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 18, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Recipient : Abilita Therapeutics

                          Deal Size : $785.0 million

                          Deal Type : Collaboration

                          Fermion Orion Company Banner