Crospovidone | Pharmaceutical Excipients for Nivolumab

SPI Pharma

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Advantol 300

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Applications: Advantol® 300 is a directly compressible pharmaceutical excipient used to create soft chew or soft melt oral dosage forms. It is a robust system that enables rapid product development.

Ingredient(s): Mannitol

Dosage Form: Orodispersible Tablet, Tablet

Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

Rochem International Inc

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Mannitol

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Applications: Mannitol is mainly used as a bulking agent in tableting. It is also used as taste masking agent in ODT formulations.

Ingredient(s): Mannitol

Dosage Form: Capsule, Tablet

Category: Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

Gangwal Chemicals

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INDIA India

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SEPITRAP 80

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Applications: Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

Ingredient(s): Magnesium aluminium silicate, Polysorbate 80

Dosage Form: Tablet, Capsule

Category: API Stability Enhancers, Direct Compression, Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: USP-NF, EP, JP & having US DMF

Technical Specifications: Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

Gangwal Chemicals

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INDIA India

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F-MELT TYPE C

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Applications: Orally Disintegrating Tablets,Sachets, Dispersible Tablets, Sachets, Chewable Tablets, Sublingual Tablets

Ingredient(s): Crospovidone, Dibasic Calcium Phosphate, Mannitol, Microcrystalline Cellulose, Xylitol Excipient

Dosage Form: Capsule, Orodispersible Tablet, Tablet

Category: Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Conforms to Japanese Pharmaceutical Excipients. All components meet USP-NF, JP, EP. US DMF Type IV filed.

Technical Specifications: Not Available

SPI Pharma

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Compressol SM

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Applications: Compressol® SM, co-processed polyol, is a directly compressible pharmaceutical excipient comprised of mannitol and sorbitol. It provides superior compactibility of sorbitol, while retaining lower hygroscopicity & a lower disintegration time.

Ingredient(s): Mannitol, Sorbitol

Dosage Form: Tablet, Orodispersible Tablet

Category: Chewable & Orodispersible Aids, Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

Kerry

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LubriTose™ Mannitol

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Applications: Standard Direct Tabletting

Ingredient(s): Glyceryl Monostearate, Mannitol

Dosage Form: Tablet

Category: Co-Processed Excipients

Route of Administration (Grade): Not Available

Pharmacopoeia Reference: NF/EP/JP

Technical Specifications: Not Available

Gangwal Chemicals

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INDIA India

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MONTANOX 80 PHA PREMIUM

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Applications: Polysorbates, TWEENs, is used as a stabilizer in aqueous formulations of medications and also as a solubilizing agent acts as a surfactant to increase the solubility in various dosge forms.

Ingredient(s): Polysorbate 80

Dosage Form: Capsule, Cream / Lotion / Ointment, Tablet

Category: Emulsifying Agents, Solubilizers, Surfactant & Foaming Agents, Topical

Route of Administration (Grade): Oral, Topical

Pharmacopoeia Reference: USP-NF, EP, JP

Technical Specifications: Non-Ionic Hydrophilic surfactant, Emulsifier (o/w emulsion), Solubilizer

SPI Pharma

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Mannogem EZ Spray-Dried

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Applications: Mannogem, a mannitol product, dissolves rapidly and can increase the rate of tablet disintegration, subsequent drug dissolution and drug release.

Ingredient(s): Mannitol

Dosage Form: Orodispersible Tablet, Tablet

Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

SPI Pharma

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Mannogem Granular

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Applications: Mannogem Granular (Mannitol) dissolves rapidly and can increase the rate of tablet disintegration, subsequent drug dissolution and drug release.

Ingredient(s): Mannitol

Dosage Form: Orodispersible Tablet, Tablet

Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

SPI Pharma

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Mannogem XL Mannitol

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Applications: Mannogem® XL is an innovative technology used to enhance mannitol formulation tabletability. It is a multifunctional, compendial grade of DC spray dried mannitol that provides superior binding and quick disintegration.

Ingredient(s): Mannitol

Dosage Form: Tablet, Orodispersible Tablet

Category: API Stability Enhancers, Chewable & Orodispersible Aids, Fillers, Diluents & Binders

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

SPI Pharma

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Pharmaburst 500

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Applications: Pharmaburst® 500 is a directly compressible pharmaceutical excipient used to create ODTs quickly & easily. It speeds up development time by providing a platform that uses API, flavor & color to finalize directly compressible dosage forms.

Ingredient(s): Mannitol

Dosage Form: Orodispersible Tablet, Tablet

Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

SPI Pharma

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Pharmasperse 416

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Applications: Pharmasperse® 416 is a versatile drug delivery system (DDS) comprised of excipients such as mannitol. It is specifically engineered to manufacture orally dispersible powder (ODP) formulations.

Ingredient(s): Mannitol

Dosage Form: Orodispersible Tablet, Tablet

Category: Chewable & Orodispersible Aids, Taste Masking

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

SPI Pharma

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Mannogem Powder

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Applications: Mannogem (Mannitol Powder) dissolves rapidly and can increase the rate of tablet disintegration, subsequent drug dissolution and drug release.

Ingredient(s): Mannitol

Dosage Form: Granule / Pellet, Tablet

Category: Fillers, Diluents & Binders, Granulation

Route of Administration (Grade): Oral

Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available