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Virtual BoothSolving Formulation Challenges Using Superior Functional Materials

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Applications: SPI® VAC Gels are based on highly engineered pseudo-boehmite and are used as vaccine adjuvants. It is a proven technology which can absorb a large range of proteins and incativated bacteria/viruses.

Ingredient(s): Aluminum Hydroxide Excipient

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

Virtual BoothBringing Life to Formulation.

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Applications: Adsorbent, Flow Aid, Moisture Protection, Stabilization of API

Ingredient(s): Magnesium Aluminometasilicate Type IA

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP-NF, JP, EP

Technical Specifications: Not Available

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Applications: Diluent; It improves hardness & disintegration

Ingredient(s): Maltose Sugar

Dosage Form: Suspension

Category: Disintegrants & Superdisintegrants, Fillers, Diluents & Binders

Route of Administration (Grade): Solid Orals, Liquids, Injections
Pharmacopoeia Reference: USP-NF, JPE, Type IV DMF

Technical Specifications: Maltose is a reducing disaccharide consisting of two glucose molecules linked by an ?-1,4 bond.

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Ingredient(s): Acesulfame Potassium Excipient

Dosage Form: Suspension

Category: Taste Masking

Route of Administration (Grade): Solidorals, Liquid Dosage
Pharmacopoeia Reference: IP/BP/EP/USP

Technical Specifications: Tastes similar to sugars, smaller amount needed for same level of sweetening of sugar, they enhance flavours.

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Ingredient(s): Neotame Excipient

Dosage Form: Suspension

Category: Taste Masking

Route of Administration (Grade): Solid Orals, Liquid Dosage
Pharmacopoeia Reference: IP/USP

Technical Specifications: Not Available

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Applications: With unique flavor, it is an important sweetening agent. Since its main ingredient is fructose and glucose, it is called “fructose-glucose syrup”.

Ingredient(s): High Fructose Corn Syrup

Dosage Form: Suspension

Category: Taste Masking

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Hydroxypropyl MethylCellulose are widely used in construction, pharmaceutical, food, cosmetic, detergent, paints, as thickener, emulsifier, film-former, binder, dispersing agent, protective colloids.

Ingredient(s): Hydroxypropyl Methyl Cellulose

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Direct compression; Powder blend, filler-binder, taste masking agent for slow to medium fast disintegrating tablets, lozenge tablets, swallowable tablets, effervescent tablets, dry suspensions (for sachet and capsule fillings)

Ingredient(s): Isomalt

Dosage Form: Suspension

Category: Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Ph. Eur., BP, USP-NF, JP

Technical Specifications: Solubility in water at 20°C (g/100g): 25; Particle size distribution (?m): d10 95, d50 220, d90 360; Bulk density (g/l): 410; Total water K. F. (%): 5,0; Loss on drying (%) (105 pa, 7 h at 25 ?C): 0,21

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Applications: Lactose is widely used as a filler and diluent in tablets and capsules, and to a more limited extent in lyophilized products and infant formulas.

Ingredient(s): Lactose Monohydrate

Dosage Form: Suspension

Category: Direct Compression

Route of Administration (Grade): Oral and Parenteral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: It can be easily dissolved in water. It has a moderate sweet taste & the sweet intensity is lower than sucrose. Its characteristics includes heat-resistance, acid-resistance, water based & anti-ferment.

Ingredient(s): Maltitol Excipient

Dosage Form: Suspension

Category: Taste Masking

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Attapulgite acts as abrasive, absorbent, anticaking agent, binder, bulking agent and viscosity increasing agent.

Ingredient(s): Attapulgite Excipient

Dosage Form: Suspension

Category: Rheology Modifiers

Route of Administration (Grade): Oral & Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Solubilizer, Dissolution Improver, Emulsifier, Masking Agent, Moisturizer, Aerosol Formulations

Ingredient(s): Polyoxyl 35 Hydrogenated Castor Oil

Dosage Form: Suspension

Category: Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Bentonite is used in topical & oral preparations, formulation of suspensions and gels, aqueous preparation, cream bases and antidote in heavy metal poisoning.

Ingredient(s): Bentonite Excipient

Dosage Form: Suspension

Category: Rheology Modifiers

Route of Administration (Grade): Oral and Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Polysorbate 80 acts as solubilizer, emulsifier and wetting agent.

Ingredient(s): Polysorbate 80

Dosage Form: Suspension

Category: Solubilizers

Route of Administration (Grade): Oral, Topical & Parenteral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Direct compression; Powder blend, filler-binder, taste masking agent for slow to very fast disintegrating tablets, chewable tablets, any kind of other tablets (also plant extracts and probiotics), dry suspensions (for sachet and capsule fillings)

Ingredient(s): Isomalt

Dosage Form: Suspension

Category: Fillers, Diluents & Binders

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Ph. Eur., BP, USP-NF, JP

Technical Specifications: Solubility in water at 20°C (g/100g): 42; Particle size distribution (?m): d10 90, d50 210, d90 360; Bulk density (g/l): 400; Total water K. F. (%): 2,9; Loss on drying (%) (105 pa, 7 h at 25 ?C): 0,12

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Applications: Magnesium aluminium silicate is used as opacifying agent, anticaking agent, viscosity agent, suspending agents.

Ingredient(s): Magnesium aluminium silicate Excipient

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Oral and Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: It is used as thickeners and stabilizers in semi-solid and liquid dosage form.

Ingredient(s): Cross Linked Sodium Carboxymethylcellulose

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: It is used as thickeners and stabilizers in semi-solid dosage form.

Ingredient(s): Xanthan Gum

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Capsule filling, Dry blend, Hot melt extrusion, Dry suspension (bottle, sachet, capsule fillings), Starter pellets

Ingredient(s): Isomalt

Dosage Form: Suspension

Category: Fillers, Diluents & Binders, Taste Masking

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Ph. Eur., BP, USP-NF, JP

Technical Specifications: Solubility in water at 20°C (g/100g): 25; Particle size distribution (?m): d10 270, d50 400, d90 530; Bulk density (g/l): 820; Total water K. F. (%): 2,3; Loss on drying (%) (105 pa, 7 h at 25 ?C): 0,12

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Applications: HiCel MCG is use in oral suspensions as a stabilizer & emulsion prepared with high shear forces. It is a good binder for tablets & excellent stabilizer as well as thickener.

Ingredient(s): Carboxymethyl cellulose sodium, Microcrystalline Cellulose

Dosage Form: Suspension

Category: Rheology Modifiers, Thickeners and Stabilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Pan coating (Sugar free), Syrup, Palatability improvement in liquid formulations

Ingredient(s): Isomalt

Dosage Form: Suspension

Category: Taste Masking

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Ph. Eur., BP, USP-NF, JP

Technical Specifications: Solubility in water at 20°C (g/100g): 42; Particle size distribution (?m): d10 260, d50 520, d90 800; Bulk density (g/l): 780; Total water K. F. (%): 2,8; Loss on drying (%) (105 pa, 7 h at 25 ?C): 0,02

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Applications: It is used in oral pharmaceuticals as a disintegrant with a rapid swelling for tablet and in capsules formulations. It is also used as a suspending agent & stabilizer.

Ingredient(s): Sodium Starch Glycolate

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Carbopol® 971P NF polymer is used in oral & mucosal contact applications such as extended/controlled release tablets, oral liquids, suspension & bioadhesive formulations. The residual solvent of Carbopol 971P NF is Ethyl acetate.

Ingredient(s): Carbomer Homopolymer Type A

Dosage Form: Suspension

Category: Thickeners and Stabilizers

Route of Administration (Grade): Oral & Topical
Pharmacopoeia Reference: United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type A, European Pharmacopeia (Ph. Eur.), India Pharmacopeia (IP), China Pharmacopeia (ChP) monographs for Carbomers.

Technical Specifications: Viscosity, cP (0.5 wt% at pH 7.5)- 4,000 - 11,000