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    Looking for Direct Compression? Find Direct Compression Agents used in Nivolumab to address drug delivery challenges on PharmaCompass.

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    01 SPI Pharma (11)

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    SPI Pharma

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    PHARMABURST 500

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    Applications:

    Pharmaburst® 500 is a directly compressible pharmaceutical excipient used to create orally disintegrating tablets quickly and easily.

    Ingredient(s): Mannitol

    Dosage Form: Orodispersible Tablet, Tablet

    Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking

    Route of Administration (Grade): Oral
    Pharmacopoeia Reference: NA

    Technical Specifications: NA

    Pharmaburst 500

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    Gangwal Healthcare

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      MANNITOL DC 200

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      Applications:

      Mannitol – DC 200, is a directly compressible grade excipient used as filler/binder to produce extremely robust tablets. It is also used capsules, syrups, suspensions, etc.

      Ingredient(s): Mannitol

      Dosage Form: Capsule, Tablet, Dry Syrup, Suspension, Syrup

      Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: IP/BP/EP/USP-NF

      Technical Specifications: NA

      Gangwal Healthcare Mannitol DC 200

      Cophex 2024

      Not Confirmed

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      SPI Pharma

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      ADVANTOL 300

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      Applications:

      Advantol® 300 is a DC pharmaceutical excipient used to create soft chewable or soft melt oral dosage forms & enables rapid product development.

      Ingredient(s): Mannitol

      Dosage Form: Orodispersible Tablet, Tablet

      Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Advantol 300

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      SPI Pharma

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      COMPRESSOL SM

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      Applications:

      Compressol® SM, co-processed polyol, is a DC excipient of mannitol & sorbitol with superior compactibility, lower disintegration time & hygroscopicity

      Ingredient(s): Mannitol, Sorbitol

      Dosage Form: Tablet, Orodispersible Tablet

      Category: Chewable & Orodispersible Aids, Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Taste Masking

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

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      SPI Pharma

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      MANNOGEM EZ SPRAY-DRIED

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      Applications:

      Mannogem EZ Spray-Dried, a mannitol product, dissolves rapidly and can increase the rate of tablet disintegration, drug dissolution & drug release.

      Ingredient(s): Mannitol

      Dosage Form: Orodispersible Tablet, Tablet

      Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Mannogem EZ Spray-Dried

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      MANNOGEM GRANULAR

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      Applications:

      Mannogem Granular (mannitol) dissolves rapidly and can increase the rate of tablet disintegration, subsequent drug dissolution and drug release.

      Ingredient(s): Mannitol

      Dosage Form: Orodispersible Tablet, Tablet

      Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Mannogem Granular

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      SPI Pharma

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      MANNOGEM® XL OPAL

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      Applications:

      Mannogem® XL Opal, directly compressible 160 µm spray-dried mannitol provides superior binding properties and tabletability.

      Ingredient(s): Mannitol

      Dosage Form: Tablet

      Category: Direct Compression, Fillers, Diluents & Binders, Taste Masking

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: 160 µm Powder Mannitol

      SPI Pharma Mannogem® XL Opal

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      Sigachi Industries

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        HICEL HFE

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        Applications:

        HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

        Ingredient(s): Mannitol, Microcrystalline Cellulose

        Dosage Form: Orodispersible Tablet

        Category: Direct Compression, Disintegrants & Superdisintegrants

        Route of Administration (Grade): Oral
        Pharmacopoeia Reference: Not Available

        Technical Specifications: Not Available
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        Microlex e.U

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          MICROLEX® MLP 520

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          Applications:

          Use in a wide range of oral applications such as wet or dry granulation, excipient of choice for flash release forms.

          Ingredient(s): Mannitol

          Dosage Form: Capsule, Tablet

          Category: Direct Compression, Fillers, Diluents & Binders, Granulation

          Route of Administration (Grade): Topical, Oral
          Pharmacopoeia Reference: Monograph- Ph.Eur, USP/NF

          Technical Specifications: Available in different particle size as 25.µ, 50.µ, 180.µ
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          Seppic

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          SEPITRAP 80

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          Solubilizer

          Ingredient(s): Polysorbate 80, Polysorbate 80

          Dosage Form: Capsule, Tablet, Dry Syrup

          Category: Co-Processed Excipients, Direct Compression, Solubilizers

          Route of Administration (Grade): Oral
          Pharmacopoeia Reference: Not Available

          Technical Specifications: Solubilizer in powder form; EXCiPACT
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          Gangwal Chemicals

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            SEPITRAP 80

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            Applications:

            Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

            Ingredient(s): Magnesium aluminium silicate Excipient, Polysorbate 80

            Dosage Form: Tablet, Capsule

            Category: API Stability Enhancers, Direct Compression, Solubilizers

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: USP-NF, EP, JP & having US DMF

            Technical Specifications: Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage
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            BASF

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            LUDIFLASH

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            Applications:

            Ludiflash is a ready-to-use orally disintegrating tablet (ODT) solution with superior mouthfeel.

            Ingredient(s): Crospovidone, Mannitol, Polyvinyl Acetate

            Dosage Form: Orodispersible Tablet

            Category: Chewable & Orodispersible Aids, Direct Compression, Granulation

            Route of Administration (Grade): Not Available
            Pharmacopoeia Reference: Ph. Eur., USP, JP: 90 % mannitol, 5 % crospovidone, 5 % polyvinyl acetate

            Technical Specifications: Not Available
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