Find Vilazodone Hydrochloride manufacturers, exporters & distributors on PharmaCompass

Vilazodone Hydrochloride

Vilazodone Hydrochloride

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

20 API Suppliers, 14 USDMF, 4 EU WC, 6 NDC API, 8 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports

DOSSIERs // Finished Dosage Formulations

27 Dossiers, 18 FDA Orange Book, 3 Canada, 6 Listed Dossiers

DRUG PRODUCT COMPOSITION

TABLET;ORAL - 10MG, TABLET;ORAL - 20MG, TABLET;ORAL - 40MG

TABLET;ORAL - 10MG
TABLET;ORAL - 20MG
TABLET;ORAL - 40MG

RELATED EXCIPIENT COMPANIES

Suppliers, 20 Kerry, 10 Sigachi Industries, 9 BASF, 9 Microlex e.U, 9 Roquette, 7 Gangwal Chemicals, 7 Gangwal Healthcare, 5 Corel Pharma Chem, 4 DFE Pharma, 3 Actylis, 3 Ideal Cures Pvt Ltd, 3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 2 Nomisma Healthcare, 2 Seqens, 2 Prachin Chemical, 2 Vasa Pharmachem, 1 SPI Pharma, 1 Pharmatrans-Sanaq, 1 DKSH, 1 Finar, 1 Aeon Procare, 1 Nanjing Well Pharmaceutical

EXCIPIENTS BY APPLICATIONS

38 Fillers, Diluents & Binders, 17 Coating Systems & Additives, 16 Direct Compression, 14 Thickeners and Stabilizers, 13 Controlled & Modified Release, 13 Lubricants & Glidants, 9 Co-Processed Excipients, 9 Granulation, 8 Disintegrants & Superdisintegrants, 8 Topical, 4 Parenteral, 4 Film Formers & Plasticizers, 4 Solubilizers, 3 Taste Masking, 2 Emulsifying Agents, 2 Chewable & Orodispersible Aids, 2 API Stability Enhancers, 1 Rheology Modifiers

GLOBAL SALES INFORMATION

6 US Medicaid Prescriptions, 3 Finished Drug Prices

MARKET PLACE

4 APIs

4 APIs

DIGITAL CONTENT

8 News

8 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

5,177

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

484.00

Annual Reports

FDF Market Place

EXCIPIENTS

105

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 163521-08-2, Vilazodone hcl, Viibryd, Vilazodone (hydrochloride), Emd-68843, Emd 68 843

Molecular Formula

C₂₆H₂₈ClN₅O₂

Molecular Weight

478.0 g/mol

InChI Key

RPZBRGFNBNQSOP-UHFFFAOYSA-N

FDA UNII

U8HTX2GK8J

A benzofuran, indole, and piperazine derivative that functions as a SEROTONIN UPTAKE INHIBITOR and partial SEROTONIN 5-HT1 RECEPTOR AGONIST. It is used as an ANTIDEPRESSIVE AGENT.

1 2D Structure

Vilazodone Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;hydrochloride

2.1.2 InChI

InChI=1S/C26H27N5O2.ClH/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32;/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32);1H

2.1.3 InChI Key

RPZBRGFNBNQSOP-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N.Cl

2.2 Other Identifiers

2.2.1 UNII

U8HTX2GK8J

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1h-indol-3-yl)butyl)-1-piperazinyl)-, Hydrochloride (1:1)

2. 5-(4-(4-(5-cyano-3-indolyl)butyl)-1-piperazinyl)benzofuran-2-carboxamide

3. 68843, Emd

4. Emb 68843

5. Emb-68843

6. Emb68843

7. Emd 68843

8. Hcl, Vilazodone

9. Hydrochloride, Vilazodone

10. Viibryd

11. Vilazodone

12. Vilazodone Hcl

2.3.2 Depositor-Supplied Synonyms

1. 163521-08-2

2. Vilazodone Hcl

3. Viibryd

4. Vilazodone (hydrochloride)

5. Emd-68843

6. Emd 68 843

7. Vilazodone Hydrochloride [usan]

8. 5-(4-(4-(5-cyano-1h-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide Hydrochloride

9. Emd 68843

10. U8htx2gk8j

11. Sb659746-a

12. 163521-08-2 (hcl)

13. Chebi:70705

14. Sb659746a

15. 5-[4-[4-(5-cyanoindol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide Hydrochloride

16. Sb 659746a

17. Sb-659746a

18. Sb-659746-a

19. Vilazodone Hydrochloride (usan)

20. 5-(4-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-yl)benzofuran-2-carboxamide, Hydrochloride

21. 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide Hydrochloride

22. 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1h-indol-3-yl)butyl)-1-piperazinyl)-, Hydrochloride (1:1)

23. 5-(4-(4-(5-cyano-1h-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide Monohydrochloride

24. 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;hydrochloride

25. 5-{4-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide Hydrochloride

26. Unii-u8htx2gk8j

27. Vilazodonei

28. 2-benzofurancarboxamide, 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-piperazinyl]-, Hydrochloride (1:1)

29. Viibryd (tn)

30. Vilazodonehydrochloride

31. Vilazodone Monohydrochloride

32. Schembl867358

33. Chembl1615374

34. Dtxsid80936833

35. Bcp11496

36. Emd68843

37. Mfcd00940014

38. S4259

39. Vilazodone Hydrochloride [mi]

40. Akos024464039

41. Ccg-213313

42. Cs-0549

43. Vilazodone Hydrochloride [mart.]

44. Vilazodone Hydrochloride [vandf]

45. Vilazodone Hydrochloride [who-dd]

46. 5-{4-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboximidic Acid--hydrogen Chloride (1/1)

47. Ac-25885

48. As-74699

49. Emd 68843;sb659746a

50. Hy-14261

51. Vilazodone Hydrochloride, >=98% (hplc)

52. A3919

53. Sw219887-1

54. V0149

55. Vilazodone Hydrochloride [orange Book]

56. D09699

57. 521v128

58. J-525160

59. Q27139037

60. 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine Hydrochloride

61. 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)piperazine Hydrochloride

62. 1-[4-(5-cyanoindol-3-yl)butyl]4-(2-carbamoyl-benzofuran-5-yl)-piperazine Hydrochloride

63. 5-(4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl)-benzofuran-2carboxamide Hydrochloride

64. 5-[4-[4-(5-cyano-1h-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide Hydrochloride

65. 4-(2-carbamoyl-1-benzofuran-5-yl)-1-[4-(5-cyano-1h-indol-3-yl)butyl]piperazin-1-ium Chloride

66. Vilazodone Hydrochloride Solution, 1.0 Mg/ml In Methanol, Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date

2006-07-28

3 Chemical and Physical Properties

Molecular Formula	C₂₆H₂₈ClN₅O₂
Molecular Weight	478.0 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Exact Mass	477.1931528 g/mol
Monoisotopic Mass	477.1931528 g/mol
Topological Polar Surface Area	102 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	729
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Viibryd
PubMed Health	Vilazodone (By mouth)
Drug Classes	Antidepressant
Drug Label	VIIBRYD Tablets for oral administration contain polymorph Form IV vilazodone hydrochloride (HCl), a selective serotonin reuptake inhibitor and a 5HT1A receptor partial agonist.Vilazodone HCl is 2-benzofurancarboxamide, 5-[4-[4-(5-cyano-1H-indol-3-yl)...
Active Ingredient	Vilazodone hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	10mg; 40mg; 20mg
Market Status	Prescription
Company	Forest Labs

2 of 2
Drug Name	Viibryd
PubMed Health	Vilazodone (By mouth)
Drug Classes	Antidepressant
Drug Label	VIIBRYD Tablets for oral administration contain polymorph Form IV vilazodone hydrochloride (HCl), a selective serotonin reuptake inhibitor and a 5HT1A receptor partial agonist.Vilazodone HCl is 2-benzofurancarboxamide, 5-[4-[4-(5-cyano-1H-indol-3-yl)...
Active Ingredient	Vilazodone hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	10mg; 40mg; 20mg
Market Status	Prescription
Company	Forest Labs

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

Selective Serotonin Reuptake Inhibitors

Compounds that specifically inhibit the reuptake of serotonin in the brain. (See all compounds classified as Selective Serotonin Reuptake Inhibitors.)

Serotonin 5-HT1 Receptor Agonists

Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes. (See all compounds classified as Serotonin 5-HT1 Receptor Agonists.)

Market Place

Home

Post Enquiry

Market Place