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Also known as: Canrenoic acid potassium salt, Canrenoate potassium, Soldactone, 2181-04-6, Kanrenol, Canrenoate (potassium)
Molecular Formula
C22H29KO4
Molecular Weight
396.6  g/mol
InChI Key
JTZQCHFUGHIPDF-RYVBEKKQSA-M
FDA UNII
M671F9NLEA

Canrenoate Potassium
A synthetic pregnadiene derivative with anti-aldosterone activity.
1 2D Structure

Canrenoate Potassium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
potassium;3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
2.1.2 InChI
InChI=1S/C22H30O4.K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25;/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25);/q;+1/p-1/t16-,17+,18+,20+,21+,22-;/m1./s1
2.1.3 InChI Key
JTZQCHFUGHIPDF-RYVBEKKQSA-M
2.1.4 Canonical SMILES
CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC4(CCC(=O)[O-])O)C.[K+]
2.1.5 Isomeric SMILES
C[C@]12CCC(=O)C=C1C=C[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(CCC(=O)[O-])O)C.[K+]
2.2 Other Identifiers
2.2.1 UNII
M671F9NLEA
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 17 Hydroxy 3 Oxo 17alpha Pregna 4,6 Diene 21 Carboxylic Acid

2. 17-hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic Acid

3. Acid, 17-hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic

4. Acid, Canrenoic

5. Canrenoate Potassium

6. Canrenoate, Potassium

7. Canrenoic Acid

8. Kalium Can. Ratiopharm

9. Kalium-can.-ratiopharm

10. Sc 14266

11. Sc-14266

12. Sc14266

13. Soldactone

14. Soludactone

15. Spiroctan

2.3.2 Depositor-Supplied Synonyms

1. Canrenoic Acid Potassium Salt

2. Canrenoate Potassium

3. Soldactone

4. 2181-04-6

5. Kanrenol

6. Canrenoate (potassium)

7. Canrenoic Acid Potassium

8. Potassium Aldadiene

9. Potassium Canrenoate [inn]

10. M671f9nlea

11. Canrenoate Potassium [usan]

12. Sc-14266

13. Mls002154212

14. Canrenone Free Acid Potassium Salt

15. Nsc-757789

16. Canrenoate Potassium (usan)

17. Soludactone

18. Apiroctan

19. Venactone

20. Kalii Canrenoas

21. Aldadiene-kalium

22. Kalium Canrenoat

23. Soldactone (tn)

24. Aldadiene-potassium

25. Canrenoato Potasico

26. Ncgc00017146-01

27. Prestwick_910

28. Canrenoate De Potassium

29. Aldadiene Potassium Salt

30. Aldadiene-kalium [german]

31. Unii-m671f9nlea

32. Dsstox_cid_25602

33. Dsstox_rid_80995

34. Dsstox_gsid_45602

35. Schembl49729

36. Kalii Canrenoas [inn-latin]

37. Potassium Canrenoate (jp17)

38. Mf 465a

39. Ccris 9164

40. Chembl1371200

41. Dtxsid2045602

42. Hy-b1582a

43. Canrenoato Potasico [inn-spanish]

44. Hms1568m18

45. Hms2095m18

46. Hms2235n14

47. Hms3712m18

48. Potassium Canrenoate [jan]

49. Einecs 218-554-9

50. Tox21_110800

51. Potassium Canrenoate [mart.]

52. Canrenoate De Potassium [inn-french]

53. Potassium Canrenoate [who-dd]

54. Akos025402245

55. Ac-6875

56. Cb 8109

57. Ccg-220148

58. Nsc 757789

59. Sc 14266

60. Smr001233495

61. Cas-2181-04-6

62. Cs-0013479

63. Canrenone Free Acid Potassium Salt [mi]

64. D01943

65. Q3655600

66. W-107518

67. Potassium 17-hydroxy-3-oxo-17-alpha-pregna-4,6-diene-21-carboxylate

68. Potassium 17-hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylate

69. Potassium 3-(17-beta-hydroxy-3-oxoandrosta-4,6-dien-17-yl)propionate

70. 17-alpha-pregna-4,6-diene-21-carboxylic Acid, 17-hydroxy-3-oxo-, Monopotassium Salt

71. Potassium 17-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylate

72. Potassium 3-(3-oxo-17-beta-hydroxy-4,6-androstadien-17-alpha-yl)propanoate

73. Pregna-4,6-diene-21-carboxylic Acid, 17-hydroxy-3-oxo-, Monopotassium Salt (17alpha)-

74. Pregna-4,6-diene-21-carboxylic Acid, 17-hydroxy-3-oxo-, Monopotassium Salt (17.alpha.)-

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 396.6 g/mol
Molecular Formula C22H29KO4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass396.17029089 g/mol
Monoisotopic Mass396.17029089 g/mol
Topological Polar Surface Area77.4 Ų
Heavy Atom Count27
Formal Charge0
Complexity713
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Mineralocorticoid Receptor Antagonists

Drugs that bind to and block the activation of MINERALOCORTICOID RECEPTORS by MINERALOCORTICOIDS such as ALDOSTERONE. (See all compounds classified as Mineralocorticoid Receptor Antagonists.)


4.2 ATC Code

C - Cardiovascular system

C03 - Diuretics

C03D - Aldosterone antagonists and other potassium-sparing agents

C03DA - Aldosterone antagonists

C03DA02 - Potassium canrenoate


API Reference Price

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06-Apr-2022
22-Apr-2025
KGS
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Average Price (USD/KGS)

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Quantity (KGS) & Unit rate (USD/KGS) over time

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API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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Looking for 2181-04-6 / Canrenoate Potassium API manufacturers, exporters & distributors?

Canrenoate Potassium manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Canrenoate Potassium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Canrenoate Potassium manufacturer or Canrenoate Potassium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Canrenoate Potassium manufacturer or Canrenoate Potassium supplier.

PharmaCompass also assists you with knowing the Canrenoate Potassium API Price utilized in the formulation of products. Canrenoate Potassium API Price is not always fixed or binding as the Canrenoate Potassium Price is obtained through a variety of data sources. The Canrenoate Potassium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Canrenoate Potassium

Synonyms

Canrenoic acid potassium salt, Soldactone, 2181-04-6, Kanrenol, Canrenoate (potassium), Canrenoic acid potassium

Cas Number

2181-04-6

Unique Ingredient Identifier (UNII)

M671F9NLEA

About Canrenoate Potassium

A synthetic pregnadiene derivative with anti-aldosterone activity.

Soludactone Manufacturers

A Soludactone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Soludactone, including repackagers and relabelers. The FDA regulates Soludactone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Soludactone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Soludactone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Soludactone Suppliers

A Soludactone supplier is an individual or a company that provides Soludactone active pharmaceutical ingredient (API) or Soludactone finished formulations upon request. The Soludactone suppliers may include Soludactone API manufacturers, exporters, distributors and traders.

click here to find a list of Soludactone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Soludactone JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Soludactone Drug Master File in Japan (Soludactone JDMF) empowers Soludactone API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Soludactone JDMF during the approval evaluation for pharmaceutical products. At the time of Soludactone JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Soludactone suppliers with JDMF on PharmaCompass.

Soludactone GMP

Soludactone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Soludactone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Soludactone GMP manufacturer or Soludactone GMP API supplier for your needs.

Soludactone CoA

A Soludactone CoA (Certificate of Analysis) is a formal document that attests to Soludactone's compliance with Soludactone specifications and serves as a tool for batch-level quality control.

Soludactone CoA mostly includes findings from lab analyses of a specific batch. For each Soludactone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Soludactone may be tested according to a variety of international standards, such as European Pharmacopoeia (Soludactone EP), Soludactone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Soludactone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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