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Chemistry

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Also known as: 494-79-1, Mel b, Arsobal, Melarsoprolum [inn-latin], Rp 3854, Einecs 207-793-4
Molecular Formula
C12H15AsN6OS2
Molecular Weight
398.3  g/mol
InChI Key
JCYZMTMYPZHVBF-UHFFFAOYSA-N
FDA UNII
ZF3786Q2E8

Melarsoprol
Arsenical used in trypanosomiases. It may cause fatal encephalopathy and other undesirable side effects.
1 2D Structure

Melarsoprol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
2.1.2 InChI
InChI=1S/C12H15AsN6OS2/c14-10-17-11(15)19-12(18-10)16-8-3-1-7(2-4-8)13-21-6-9(5-20)22-13/h1-4,9,20H,5-6H2,(H5,14,15,16,17,18,19)
2.1.3 InChI Key
JCYZMTMYPZHVBF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1C(S[As](S1)C2=CC=C(C=C2)NC3=NC(=NC(=N3)N)N)CO
2.2 Other Identifiers
2.2.1 UNII
ZF3786Q2E8
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Arsobal

2. Mel B

3. Melarsenoxid Bal

4. Melarsenoxid-bal

5. Melarsenoxidbal

2.3.2 Depositor-Supplied Synonyms

1. 494-79-1

2. Mel B

3. Arsobal

4. Melarsoprolum [inn-latin]

5. Rp 3854

6. Einecs 207-793-4

7. Rp-3854

8. [2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol

9. Chebi:6729

10. Zf3786q2e8

11. Melarsoprol (inn)

12. Melarsoprol [inn]

13. 2-(p-(4,6-diamino-s-triazin-2-ylamino)phenyl)-1,3,2-dithiarsolane-4-methanol

14. Melarsoprolum

15. (2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-1,3,2-dithiarsolan-4-yl)methanol

16. (2-{4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl}-1,3,2-dithiarsolan-4-yl)methanol

17. Melarsoprol [inn:ban:dcf]

18. Specia

19. Unii-zf3786q2e8

20. Melarsoprol [mi]

21. Mel B (tn)

22. Chembl166

23. 1,3,2-dithiarsolane-4-methanol, 2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-

24. Melarsoprol [mart.]

25. Schembl61707

26. Melarsoprol [who-dd]

27. Dtxsid90862033

28. Db12864

29. C08001

30. D00832

31. Q419753

32. 2-[4-{(4,6-diamino-1,3,5-triazin-2-yl)amino}phenyl]-1,3,2-dithiarsolan-e-4-methanol

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 398.3 g/mol
Molecular Formula C12H15AsN6OS2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count4
Exact Mass397.996471 g/mol
Monoisotopic Mass397.996471 g/mol
Topological Polar Surface Area174 Ų
Heavy Atom Count22
Formal Charge0
Complexity353
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Trypanocidal Agents

Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA. (See all compounds classified as Trypanocidal Agents.)


4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P01 - Antiprotozoals

P01C - Agents against leishmaniasis and trypanosomiasis

P01CD - Arsenic compounds

P01CD01 - Melarsoprol


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ABOUT THIS PAGE

Looking for 494-79-1 / Melarsoprol API manufacturers, exporters & distributors?

Melarsoprol manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Melarsoprol API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Melarsoprol manufacturer or Melarsoprol supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Melarsoprol manufacturer or Melarsoprol supplier.

PharmaCompass also assists you with knowing the Melarsoprol API Price utilized in the formulation of products. Melarsoprol API Price is not always fixed or binding as the Melarsoprol Price is obtained through a variety of data sources. The Melarsoprol Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Melarsoprol

Synonyms

494-79-1, Mel b, Arsobal, Melarsoprolum [inn-latin], Rp 3854, Einecs 207-793-4

Cas Number

494-79-1

Unique Ingredient Identifier (UNII)

ZF3786Q2E8

About Melarsoprol

Arsenical used in trypanosomiases. It may cause fatal encephalopathy and other undesirable side effects.

Melarsoprol Manufacturers

A Melarsoprol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Melarsoprol, including repackagers and relabelers. The FDA regulates Melarsoprol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Melarsoprol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Melarsoprol Suppliers

A Melarsoprol supplier is an individual or a company that provides Melarsoprol active pharmaceutical ingredient (API) or Melarsoprol finished formulations upon request. The Melarsoprol suppliers may include Melarsoprol API manufacturers, exporters, distributors and traders.

Melarsoprol GMP

Melarsoprol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Melarsoprol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Melarsoprol GMP manufacturer or Melarsoprol GMP API supplier for your needs.

Melarsoprol CoA

A Melarsoprol CoA (Certificate of Analysis) is a formal document that attests to Melarsoprol's compliance with Melarsoprol specifications and serves as a tool for batch-level quality control.

Melarsoprol CoA mostly includes findings from lab analyses of a specific batch. For each Melarsoprol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Melarsoprol may be tested according to a variety of international standards, such as European Pharmacopoeia (Melarsoprol EP), Melarsoprol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Melarsoprol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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