Find Tovinontrine manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 2062661-53-2, Imr-687, Tovinontrine [usan], Ck1598, Af68722, W248y1akor
Molecular Formula
C21H26N6O2
Molecular Weight
394.5  g/mol
InChI Key
GWGNPYYVGANHRJ-GDBMZVCRSA-N
FDA UNII
W248Y1AKOR

Tovinontrine
IMR-687 is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
1 2D Structure

Tovinontrine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-(oxan-4-yl)-7H-imidazo[1,5-a]pyrazin-8-one
2.1.2 InChI
InChI=1S/C21H26N6O2/c1-14-10-26(13-19-22-5-2-6-23-19)11-16(14)17-12-27-18(21(28)25-17)9-24-20(27)15-3-7-29-8-4-15/h2,5-6,9,12,14-16H,3-4,7-8,10-11,13H2,1H3,(H,25,28)/t14-,16-/m1/s1
2.1.3 InChI Key
GWGNPYYVGANHRJ-GDBMZVCRSA-N
2.1.4 Canonical SMILES
CC1CN(CC1C2=CN3C(=CN=C3C4CCOCC4)C(=O)N2)CC5=NC=CC=N5
2.1.5 Isomeric SMILES
C[C@@H]1CN(C[C@H]1C2=CN3C(=CN=C3C4CCOCC4)C(=O)N2)CC5=NC=CC=N5
2.2 Other Identifiers
2.2.1 UNII
W248Y1AKOR
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2062661-53-2

2. Imr-687

3. Tovinontrine [usan]

4. Ck1598

5. Af68722

6. W248y1akor

7. Imr687

8. Ck-1598

9. Af-68722

10. 6-((3s,4s)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-tetrahydropyran-4-yl-7himidazo(1,5-a)pyrazin-8-one

11. Imidazo(1,5-a)pyrazin-8(7h)-one, 6-((3s,4s)-4-methyl-1-(2-pyrimidinylmethyl)-3-pyrrolidinyl)-3-(tetrahydro-2h-pyran-4-yl)-

12. Tovinontrine [inn]

13. Unii-w248y1akor

14. Tovinontrine [who-dd]

15. Chembl4297290

16. Schembl20358493

17. Bdbm426313

18. Ex-a5357

19. Us10513524, Compound (p3

20. Who 11327

21. Hy-109193

22. Cs-0119133

23. 6-((3s,4s)-4-methyl-1-(2-pyrimidinylmethyl)-3-pyrrolidinyl)-3-(tetrahydro-2h-pyran-4-yl)imidazo(1,5-a)pyrazin-8(7h)-one

24. 6-[(3s,4s)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-(oxan-4-yl)-7h-imidazo[1,5-a]pyrazin-8-one

2.4 Create Date
2017-03-16
3 Chemical and Physical Properties
Molecular Weight 394.5 g/mol
Molecular Formula C21H26N6O2
XLogP30.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass394.21172409 g/mol
Monoisotopic Mass394.21172409 g/mol
Topological Polar Surface Area85.2 Ų
Heavy Atom Count29
Formal Charge0
Complexity631
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 2062661-53-2 / Tovinontrine API manufacturers, exporters & distributors?

Tovinontrine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Tovinontrine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tovinontrine manufacturer or Tovinontrine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tovinontrine manufacturer or Tovinontrine supplier.

PharmaCompass also assists you with knowing the Tovinontrine API Price utilized in the formulation of products. Tovinontrine API Price is not always fixed or binding as the Tovinontrine Price is obtained through a variety of data sources. The Tovinontrine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Tovinontrine

Synonyms

2062661-53-2, Imr-687, Tovinontrine [usan], Ck1598, Af68722, W248y1akor

Cas Number

2062661-53-2

Unique Ingredient Identifier (UNII)

W248Y1AKOR

About Tovinontrine

IMR-687 is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).

IMR-687 Manufacturers

A IMR-687 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of IMR-687, including repackagers and relabelers. The FDA regulates IMR-687 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. IMR-687 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

IMR-687 Suppliers

A IMR-687 supplier is an individual or a company that provides IMR-687 active pharmaceutical ingredient (API) or IMR-687 finished formulations upon request. The IMR-687 suppliers may include IMR-687 API manufacturers, exporters, distributors and traders.

IMR-687 GMP

IMR-687 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of IMR-687 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right IMR-687 GMP manufacturer or IMR-687 GMP API supplier for your needs.

IMR-687 CoA

A IMR-687 CoA (Certificate of Analysis) is a formal document that attests to IMR-687's compliance with IMR-687 specifications and serves as a tool for batch-level quality control.

IMR-687 CoA mostly includes findings from lab analyses of a specific batch. For each IMR-687 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

IMR-687 may be tested according to a variety of international standards, such as European Pharmacopoeia (IMR-687 EP), IMR-687 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (IMR-687 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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