List of Korea Drug Master Files (KDMF) for Eperisone Hydrochloride Active Pharmaceutical Ingredient submitted to the Review Authority in Korea and listed on PharmaCompass.com

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 56839-43-1, Eperisone hcl, Myonal, Mional, Empp, Eperisone, hcl

Molecular Formula

C₁₇H₂₆ClNO

Molecular Weight

295.8 g/mol

InChI Key

GTAXGNCCEYZRII-UHFFFAOYSA-N

FDA UNII

U38O8U7P6X

Eperisone Hydrochloride

1 2D Structure

Eperisone Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(4-ethylphenyl)-2-methyl-3-piperidin-1-ylpropan-1-one;hydrochloride

2.1.2 InChI

InChI=1S/C17H25NO.ClH/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18;/h7-10,14H,3-6,11-13H2,1-2H3;1H

2.1.3 InChI Key

GTAXGNCCEYZRII-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2.Cl

2.2 Other Identifiers

2.2.1 UNII

U38O8U7P6X

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (4'-ethyl-2-methyl-3-piperidino)propiophenone

2. 4-empp

3. E-0646

4. Eperisone

2.3.2 Depositor-Supplied Synonyms

1. 56839-43-1

2. Eperisone Hcl

3. Myonal

4. Mional

5. Empp

6. Eperisone, Hcl

7. E-646

8. 1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one Hydrochloride

9. Eperisone Hydrochloride [jan]

10. 4'-ethyl-2-methyl-3-piperidinopropiophenone Hydrochloride

11. U38o8u7p6x

12. 1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride

13. 1-(4-ethylphenyl)-2-methyl-3-piperidin-1-ylpropan-1-one;hydrochloride

14. Dsstox_cid_27822

15. Dsstox_rid_82585

16. Dsstox_gsid_47844

17. Cas-56839-43-1

18. Ncgc00167973-01

19. (4'-ethyl-2-methyl-3-piperidino)propiophenone

20. Unii-u38o8u7p6x

21. E 0646

22. Epenard (tn)

23. 1-propanone, 1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)-, Hydrochloride

24. Eperisonehydrochloride

25. Dw-1030

26. Schembl218337

27. Chembl2360601

28. Dtxsid8047844

29. Eperisone Hydrochloride (jp17)

30. Chebi:31540

31. Bcp11969

32. Hy-b1901

33. Propiophenone, 4'-ethyl-2-methyl-3-piperidino-, Hydrochloride

34. Eperisone Hydrochloride [mi]

35. Tox21_112599

36. Mfcd00941459

37. Akos015843965

38. Tox21_112599_1

39. Ccg-267425

40. Eperisone Hydrochloride [mart.]

41. Ks-5241

42. Eperisone Hydrochloride [who-dd]

43. Ncgc00167973-02

44. Ac-15896

45. Db-052975

46. Cs-0013960

47. E2000

48. Ft-0602324

49. S4877

50. D01671

51. D95097

52. E-2000

53. A831198

54. Q27889924

55. 1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-onehydrochloride

56. 1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-one Hydrochloride;eperisone Hcl

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₇H₂₆ClNO
Molecular Weight	295.8 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	295.1702921 g/mol
Monoisotopic Mass	295.1702921 g/mol
Topological Polar Surface Area	20.3 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	275
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anticonvulsants

Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

Calcium Channel Blockers

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

Muscle Relaxants, Central

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)

Parasympatholytics

Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

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PRADESH","supplier":"EISAI","supplierCountry":"JAPAN","foreign_port":"N\/A","customer":"EISAI","customerCountry":"INDIA","quantity":"1316.00","actualQuantity":"1316","unit":"KGS","unitRateFc":"140.5","totalValueFC":"187405","currency":"USD","unitRateINR":"11825.7","date":"14-Nov-2023","totalValueINR":"15562615","totalValueInUsd":"187405","indian_port":"Vizag-RPCIPL SEZ","hs_no":"29333990","bill_no":"1001881","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"PLOT NO.135, DR.NO.10-153\/1,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718908200,"product":"EPERISONE HYDROCHLORIDE, LOT NO.202312019A","address":"PLOT NO.135, DR.NO.10-153\/1,","city":"VISAKHAPATNAM, ANDHRA PRADESH","supplier":"EISAI","supplierCountry":"JAPAN","foreign_port":"N\/A","customer":"EISAI","customerCountry":"INDIA","quantity":"1300.00","actualQuantity":"1300","unit":"KGS","unitRateFc":"133.5","totalValueFC":"176181.1","currency":"USD","unitRateINR":"11254.3","date":"21-Jun-2024","totalValueINR":"14630549","totalValueInUsd":"176181.1","indian_port":"Vizag-RPCIPL SEZ","hs_no":"29333990","bill_no":"1000993","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"KOISHIKAWA 04-06-2010 JP","customerAddress":"PLOT NO.135, DR.NO.10-153\/1,"}]

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APIs

Eperison HCl (1 MT) API needed in South Korea [ENA18360]

A company that deals in various pharmaceutical products is looking for suppliers of Eperison HCl (1 MT) API for commercial purposes. The suppliers must support this enquiry with CoA.

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17 Oct 2023

Eperisone HCl (2 kg) API needed in Sudan [ENA15757]

A company that focuses on the development, manufacturing, marketing and distribution of various branded pharmaceutical products is looking for suppliers of Eperisone HCl (2 kg) API for development purposes. The suppliers must support this enquiry with CoA.

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07 Dec 2022

Various APIs needed Philippines [ENA13896]

A company that aims to become a global leader as a manufacturer of health care products by providing solutions is looking for suppliers of Various APIs for development purpose. The suppliers must support this enquiry with GMP & CoA. 1. Mefenamic Acid (5 kg) API 2. Amorphous Dapagliflozin (250 g) API 3. Beclomethasone (500 g) API 4. Eperisone Hydrochloride (1 kg) API 5. Indacaterol Maleate (200 g) API

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08 Jun 2022

PharmaCompass

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Eperisone Hydrochloride Manufacturers | Traders | Suppliers

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