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ACTIVE PHARMA INGREDIENTS

72 API Suppliers, 23 USDMF, 10 CEP/COS, 1 JDMF, 23 EU WC, 16 KDMF, 16 NDC API, 53 Listed Suppliers, $ API Reference Price

72 API Suppliers
23 USDMF
10 CEP/COS
1 JDMF
23 EU WC
16 KDMF
16 NDC API
53 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

INTERMEDIATES

28 Intermediates Suppliers

28 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

375 FDF Dossiers, 107 FDA Orange Book, 46 Europe, 30 Canada, 144 Australia, 7 South Africa, 41 Listed Dossiers

375 FDF Dossiers
107 FDA Orange Book
46 Europe
30 Canada
144 Australia
7 South Africa
41 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

GRANULE;ORAL - 180MG, GRANULE;ORAL - 360MG, GRANULE;ORAL - 90MG

drugProductComposition
GRANULE;ORAL - 180MG
GRANULE;ORAL - 360MG
GRANULE;ORAL - 90MG

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 1 DKSH, 3 Boai NKY Pharmaceuticals Ltd, 8 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 6 BASF, 4 DFE Pharma, 4 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 17 Kerry, 9 Microlex e.U, 1 Nanjing Bold Chemical, 1 Pharmatrans-Sanaq, 3 Pluviaendo, 2 Prachin Chemical, 7 Roquette, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 9 Sigachi Industries, 1 Ulanqab Kema New Material, 2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

42 Fillers, Diluents & Binders, 20 Direct Compression, 14 Lubricants & Glidants, 13 Co-Processed Excipients, 12 Granulation, 12 Thickeners and Stabilizers, 5 Controlled & Modified Release, 5 Disintegrants & Superdisintegrants, 4 Taste Masking, 4 Emulsifying Agents, 4 Coating Systems & Additives, 2 API Stability Enhancers, 2 Solubilizers, 2 Topical, 2 Chewable & Orodispersible Aids, 2 Parenteral, 2 Film Formers & Plasticizers, 1 Surfactant & Foaming Agents, 1 Rheology Modifiers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 58 NEWS #PharmaBuzz

media
3 DATA COMPILATION #PharmaFlow
58 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

3 US Medicaid Prescriptions, 42 Finished Drug Prices, 1 Annual Reports

globalSalesInformation
3 US Medicaid Prescriptions
42 Finished Drug Prices
1 Annual Reports

MARKET PLACE

10 APIs, 3 FDF Dossiers

marketPlace
10 APIs
3 FDF Dossiers

PATENTS & EXCLUSIVITIES

3 US Patents, 6 Health Canada Patents

patents
3 US Patents
6 Health Canada Patents

REF. STANDARDS & IMPURITIES

16 Others

otherSolutions
16 Others

Synnat Deferasirox

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 408

MARKET PLACE

API

FDF

28INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

375

FDF Dossiers

107

FDA Orange Book

Europe

Canada

144

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

68,959,338

Annual Reports (USD Million)

323

Finished Drug Prices

89 RELATED EXCIPIENT COMPANIES

149EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:

Molecular Formula

C₂₁H₁₅N₃O₄

Molecular Weight

373.4 g/mol

InChI Key

FMSOAWSKCWYLBB-VBGLAJCLSA-N

1 2D Structure

Deferasirox

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[(3Z,5E)-3,5-bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl]benzoic acid

2.1.2 InChI

InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,22-23H,(H,27,28)/b19-15-,20-16+

2.1.3 InChI Key

FMSOAWSKCWYLBB-VBGLAJCLSA-N

2.1.4 Canonical SMILES

C1=CC(=C2NC(=C3C=CC=CC3=O)N(N2)C4=CC=C(C=C4)C(=O)O)C(=O)C=C1

2.1.5 Isomeric SMILES

C1=C/C(=C/2\N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1

2.2 Create Date

2005-08-09

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₁₅N₃O₄
Molecular Weight	373.4 g/mol
XLogP3	3.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	373.10625597 g/mol
Monoisotopic Mass	373.10625597 g/mol
Topological Polar Surface Area	98.7 A^2
Heavy Atom Count	28
Formal Charge	0
Complexity	912
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Exjade
PubMed Health	Deferasirox (By mouth)
Drug Classes	Heavy Metal Chelator
Drug Label	Exjade(deferasirox) is an iron chelating agent. Exjade tablets for oral suspension contain 125mg, 250mg, or 500mg deferasirox. Deferasirox is designated chemically as 4-[3,5-Bis (2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-benzoic acid and its st...
Active Ingredient	Deferasirox
Dosage Form	Tablet, for suspension
Route	Oral
Strength	250mg; 125mg; 500mg
Market Status	Prescription
Company	Novartis

2 of 2
Drug Name	Exjade
PubMed Health	Deferasirox (By mouth)
Drug Classes	Heavy Metal Chelator
Drug Label	Exjade(deferasirox) is an iron chelating agent. Exjade tablets for oral suspension contain 125mg, 250mg, or 500mg deferasirox. Deferasirox is designated chemically as 4-[3,5-Bis (2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-benzoic acid and its st...
Active Ingredient	Deferasirox
Dosage Form	Tablet, for suspension
Route	Oral
Strength	250mg; 125mg; 500mg
Market Status	Prescription
Company	Novartis

API SUPPLIERS

01

Synnat Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #2F17

Synnat Pharma is one of the leading active pharmaceutical ingredients and intermediates manufacturers.

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India

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02

Bal Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #2D82

Bal Pharma, leading manufacturer of niche & specialty API, Intermediates and Finished Formulations.

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India

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03

Zhejiang Hengkang Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3B118

Zhejiang Hengkang Pharm Group is a dynamic pharmaceutical entity, spanning drug research, large-scale production, and global marketing.

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China

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04

LGM Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Contract Pharma 2024

Booth #134

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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U.S.A

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05

DKSH

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #6C42

DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.

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Switzerland

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06

Gonane Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Gonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

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India

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07

Jai Radhe Sales

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Jai Radhe Sales is your partner for all your sourcing needs.

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India

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08

Aarti Pharmalabs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3F17

Aarti Pharmalabs is a partner of choice for APIs & Intermediates and the largest Indian manufacturer of Xanthine Derivatives.

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India

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09

HRV Global Life Sciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A25

HRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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India

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AUDIT

10

Neuland Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #1A18

Neuland Laboratories- A dedicated 100% API provider.

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India

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USDMF

CEP/COS

JDMF EU-WC

NDC

KDMF

VMF Others AUDIT

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API Reference Price

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ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1639593000,"product":"413107,DEFERASIROX BATCH:RT1076,RT1083,RT1086,RT1087,RT1088(PHARMACEUTICAL PRODUCTS)","address":"SITE NO.1,BOMMASANDRA INDL.AREA,IV ,PHASE,JIGANI LINK ROAD ANEKAL TALU","city":"BANGALORE,KARNATAKA","supplier":"APOTEX INC","supplierCountry":"CANADA","foreign_port":"TORONTO","customer":"APOTEX INC","customerCountry":"INDIA","quantity":"248.21","actualQuantity":"248.208","unit":"KGS","unitRateFc":"974.7","totalValueFC":"243460.1","currency":"USD","unitRateINR":"73983.4","date":"16-Dec-2021","totalValueINR":"18363261.18","totalValueInUsd":"243460.1","indian_port":"BANGALORE AIR","hs_no":"29339990","bill_no":"6703969","productDescription":"API","marketType":"REGULATED MARKET","country":"CANADA","selfForZScoreResived":"Pharma Grade","supplierPort":"TORONTO","supplierAddress":"","customerAddress":"SITE NO.1,BOMMASANDRA INDL.AREA,IV ,PHASE,JIGANI LINK ROAD ANEKAL TALU"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1649442600,"product":"413107,DEFERASIROX LOT:RF6910 (PHARMACEUTICAL PRODUCTS)","address":"SITE NO.1,BOMMASANDRA INDL.AREA,IV ,PHASE,JIGANI LINK ROAD ANEKAL TALU","city":"BANGALORE,KARNATAKA","supplier":"APOTEX INC","supplierCountry":"CANADA","foreign_port":"NA","customer":"APOTEX INC","customerCountry":"INDIA","quantity":"48.45","actualQuantity":"48.454","unit":"KGS","unitRateFc":"969","totalValueFC":"47792.7","currency":"USD","unitRateINR":"74419.2","date":"09-Apr-2022","totalValueINR":"3605908.22","totalValueInUsd":"47792.7","indian_port":"BANGALORE AIR","hs_no":"29339990","bill_no":"8208329","productDescription":"API","marketType":"REGULATED MARKET","country":"CANADA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SITE NO.1,BOMMASANDRA INDL.AREA,IV ,PHASE,JIGANI LINK ROAD ANEKAL TALU"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703788200,"product":"DEFERASIROX RELATED COMPOUND F (QTY:7 X 0.025 G, VALUE: USD18.11\/EACH) (FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL ","supplierCountry":"INDIA","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.000175","unit":"KGS","unitRateFc":"724400","totalValueFC":"142.4","currency":"USD","unitRateINR":"67567142.9","date":"29-Dec-2023","totalValueINR":"11824.25","totalValueInUsd":"142.4","indian_port":"Hyderabad Air","hs_no":"29280090","bill_no":"9459630","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - GRANULE;ORAL - 180MG

USFDA APPLICATION NUMBER - 207968

DOSAGE - GRANULE;ORAL - 360MG

USFDA APPLICATION NUMBER - 207968

DOSAGE - GRANULE;ORAL - 90MG

USFDA APPLICATION NUMBER - 207968

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Fillers, Diluents & Binders

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Controlled & Modified Release

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ABOUT THIS PAGE

Deferasirox Manufacturers | Traders | Suppliers

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List of Drug Master Files (DMF) of Deferasirox Active Pharmaceutical Ingredient listed on PharmaCompass.com

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

72 API Suppliers

23 USDMF

10 CEP/COS

1 JDMF

23 EU WC

16 KDMF

16 NDC API

53 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

2 Drugs in Development

INTERMEDIATES

28 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

375 FDF Dossiers

107 FDA Orange Book

46 Europe

30 Canada

144 Australia

7 South Africa

41 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

GRANULE;ORAL - 180MG

GRANULE;ORAL - 360MG

GRANULE;ORAL - 90MG

RELATED EXCIPIENT COMPANIES

1 SPI Pharma

1 DKSH

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8 Gangwal Healthcare

2 Nanjing Well Pharmaceutical

3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

6 BASF

4 DFE Pharma

4 Gangwal Chemicals

1 Ideal Cures Pvt Ltd

17 Kerry

9 Microlex e.U

1 Nanjing Bold Chemical

1 Pharmatrans-Sanaq

3 Pluviaendo

2 Prachin Chemical

7 Roquette

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Shanghai Welltone Material Technology Co., Ltd

9 Sigachi Industries

1 Ulanqab Kema New Material

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

42 Fillers, Diluents & Binders

20 Direct Compression

14 Lubricants & Glidants

13 Co-Processed Excipients

12 Granulation

12 Thickeners and Stabilizers

5 Controlled & Modified Release

5 Disintegrants & Superdisintegrants

4 Taste Masking

4 Emulsifying Agents

4 Coating Systems & Additives

2 API Stability Enhancers

2 Solubilizers

2 Topical

2 Chewable & Orodispersible Aids

2 Parenteral

2 Film Formers & Plasticizers

1 Surfactant & Foaming Agents

1 Rheology Modifiers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow

58 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

3 US Medicaid Prescriptions

42 Finished Drug Prices