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Chemistry

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Also known as: 2380321-51-5, Pf-07220060, (3s,4r)-4-((5-chloro-4-(4-fluoro-2-(2-hydroxypropan-2-yl)-1-isopropyl-1h-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)tetrahydro-2h-pyran-3-ol, Atirmociclib, Atirmociclib [usan], S743goj5lj
Molecular Formula
C22H27ClFN5O3
Molecular Weight
463.9  g/mol
InChI Key
QYJLBHRAPDJOSO-NVXWUHKLSA-N
FDA UNII
S743GOJ5LJ

Atirmociclib
1 2D Structure

Atirmociclib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3S,4R)-4-[[5-chloro-4-[7-fluoro-2-(2-hydroxypropan-2-yl)-3-propan-2-ylbenzimidazol-5-yl]pyrimidin-2-yl]amino]oxan-3-ol
2.1.2 InChI
InChI=1S/C22H27ClFN5O3/c1-11(2)29-16-8-12(7-14(24)19(16)27-20(29)22(3,4)31)18-13(23)9-25-21(28-18)26-15-5-6-32-10-17(15)30/h7-9,11,15,17,30-31H,5-6,10H2,1-4H3,(H,25,26,28)/t15-,17-/m1/s1
2.1.3 InChI Key
QYJLBHRAPDJOSO-NVXWUHKLSA-N
2.1.4 Canonical SMILES
CC(C)N1C2=C(C(=CC(=C2)C3=NC(=NC=C3Cl)NC4CCOCC4O)F)N=C1C(C)(C)O
2.1.5 Isomeric SMILES
CC(C)N1C2=C(C(=CC(=C2)C3=NC(=NC=C3Cl)N[C@@H]4CCOC[C@H]4O)F)N=C1C(C)(C)O
2.2 Other Identifiers
2.2.1 UNII
S743GOJ5LJ
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2380321-51-5

2. Pf-07220060

3. (3s,4r)-4-((5-chloro-4-(4-fluoro-2-(2-hydroxypropan-2-yl)-1-isopropyl-1h-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)tetrahydro-2h-pyran-3-ol

4. Atirmociclib

5. Atirmociclib [usan]

6. S743goj5lj

7. Chembl5187755

8. Schembl21522680

9. Cdk4/6-in-6?

10. Bdbm462118

11. Ex-a5365

12. Us10766884, Example A35

13. Us10766884, Example A94

14. Akos040757637

15. At40871

16. Ms-28536

17. Pf 07220060 [who-dd]

18. Hy-139450

19. Cs-0201514

20. Pf07220060

21. (3s,4r)-4-({5-chloro-4-[7-fluoro-2-(2-hydroxypropan-2-yl)-3-(propan-2-yl)benzimidazol-5-yl]pyrimidin-2-yl}amino)oxan-3-ol

22. (3s,4r)-4-(5-chloro-4-(4-fluoro-2-(2-hydroxypropan-2-yl)-1-isopropyl-1h-benzo[d]imidazol-6-yl)pyrimidin-2-ylamino)tetrahydro-2h-pyran-3-ol

23. D-threo-pentitol, 1,5-anhydro-3-[[5-chloro-4-[4-fluoro-2-(1-hydroxy-1-methylethyl)-1-(1-methylethyl)-1h-benzimidazol-6-yl]-2-pyrimidinyl]amino]-2,3-dideoxy-

2.4 Create Date
2020-06-27
3 Chemical and Physical Properties
Molecular Weight 463.9 g/mol
Molecular Formula C22H27ClFN5O3
XLogP32.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area105
Heavy Atom Count32
Formal Charge0
Complexity647
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for / Atirmociclib API manufacturers, exporters & distributors?

Atirmociclib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Atirmociclib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Atirmociclib manufacturer or Atirmociclib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Atirmociclib manufacturer or Atirmociclib supplier.

PharmaCompass also assists you with knowing the Atirmociclib API Price utilized in the formulation of products. Atirmociclib API Price is not always fixed or binding as the Atirmociclib Price is obtained through a variety of data sources. The Atirmociclib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Atirmociclib

Synonyms

2380321-51-5, Pf-07220060, (3s,4r)-4-((5-chloro-4-(4-fluoro-2-(2-hydroxypropan-2-yl)-1-isopropyl-1h-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)tetrahydro-2h-pyran-3-ol, Atirmociclib [usan], S743goj5lj, Chembl5187755

Unique Ingredient Identifier (UNII)

S743GOJ5LJ

ATIRMOCICLIB [USAN] Manufacturers

A ATIRMOCICLIB [USAN] manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of ATIRMOCICLIB [USAN], including repackagers and relabelers. The FDA regulates ATIRMOCICLIB [USAN] manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. ATIRMOCICLIB [USAN] API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

ATIRMOCICLIB [USAN] Suppliers

A ATIRMOCICLIB [USAN] supplier is an individual or a company that provides ATIRMOCICLIB [USAN] active pharmaceutical ingredient (API) or ATIRMOCICLIB [USAN] finished formulations upon request. The ATIRMOCICLIB [USAN] suppliers may include ATIRMOCICLIB [USAN] API manufacturers, exporters, distributors and traders.

ATIRMOCICLIB [USAN] GMP

ATIRMOCICLIB [USAN] Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of ATIRMOCICLIB [USAN] GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right ATIRMOCICLIB [USAN] GMP manufacturer or ATIRMOCICLIB [USAN] GMP API supplier for your needs.

ATIRMOCICLIB [USAN] CoA

A ATIRMOCICLIB [USAN] CoA (Certificate of Analysis) is a formal document that attests to ATIRMOCICLIB [USAN]'s compliance with ATIRMOCICLIB [USAN] specifications and serves as a tool for batch-level quality control.

ATIRMOCICLIB [USAN] CoA mostly includes findings from lab analyses of a specific batch. For each ATIRMOCICLIB [USAN] CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

ATIRMOCICLIB [USAN] may be tested according to a variety of international standards, such as European Pharmacopoeia (ATIRMOCICLIB [USAN] EP), ATIRMOCICLIB [USAN] JP (Japanese Pharmacopeia) and the US Pharmacopoeia (ATIRMOCICLIB [USAN] USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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