Find Danuglipron manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

API REF. PRICE (USD/KG)

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GLOBAL SALES INFORMATION

US Medicaid

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Chemistry

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Also known as: Pf-06882961, 2230198-02-2, Danuglipron [usan], Dn9iui24gp, (s)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1h-benzo[d]imidazole-6-carboxylic acid, 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2s)-oxetan-2-yl]methyl}-1h-benzimidazole-6-carboxylic acid
Molecular Formula
C31H30FN5O4
Molecular Weight
555.6  g/mol
InChI Key
HYBAKUMPISVZQP-DEOSSOPVSA-N
FDA UNII
DN9IUI24GP

Danuglipron
PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).
1 2D Structure

Danuglipron

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl]piperidin-1-yl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic acid
2.1.2 InChI
InChI=1S/C31H30FN5O4/c32-25-14-20(16-33)4-5-23(25)19-41-30-3-1-2-26(35-30)21-8-11-36(12-9-21)18-29-34-27-7-6-22(31(38)39)15-28(27)37(29)17-24-10-13-40-24/h1-7,14-15,21,24H,8-13,17-19H2,(H,38,39)/t24-/m0/s1
2.1.3 InChI Key
HYBAKUMPISVZQP-DEOSSOPVSA-N
2.1.4 Canonical SMILES
C1CN(CCC1C2=NC(=CC=C2)OCC3=C(C=C(C=C3)C#N)F)CC4=NC5=C(N4CC6CCO6)C=C(C=C5)C(=O)O
2.1.5 Isomeric SMILES
C1CO[C@@H]1CN2C3=C(C=CC(=C3)C(=O)O)N=C2CN4CCC(CC4)C5=NC(=CC=C5)OCC6=C(C=C(C=C6)C#N)F
2.2 Other Identifiers
2.2.1 UNII
DN9IUI24GP
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Pf-06882961

2. 2230198-02-2

3. Danuglipron [usan]

4. Dn9iui24gp

5. (s)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1h-benzo[d]imidazole-6-carboxylic Acid

6. 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2s)-oxetan-2-yl]methyl}-1h-benzimidazole-6-carboxylic Acid

7. 1h-benzimidazole-6-carboxylic Acid, 2-((4-(6-((4-cyano-2-fluorophenyl)methoxy)-2-pyridinyl)-1-piperidinyl)methyl)-1-((2s)-2-oxetanylmethyl)-

8. Uk4

9. Danuglipron [who-dd]

10. Unii-dn9iui24gp

11. Danuglipron [inn]

12. Chembl4518483

13. Schembl20266351

14. Gtpl12064

15. Bdbm349662

16. Dtxsid601101457

17. Ex-a3607

18. Mfcd32661373

19. S9851

20. Who 11630

21. Akos040734445

22. As-0827

23. Us10208019, Example 1a-09

24. Us10208019, Example 4a-01

25. Ac-31472

26. Pf6882961

27. Pf06882961

28. Q63141738

29. 2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-((2s)-oxetan-2- Ylmethyl)-1h-benzimidazole-6-carboxylic Acid

30. 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2s)-oxetan-2-yl]methyl}-1h-1,3-benzodiazole-6-carboxylic Acid

31. 2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyridyl]-1-piperidyl]methyl]-3-[[(2s)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic Acid

32. 2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2s)-2-oxetanylmethyl]-1h-benzimidazole-6-carboxylic Acid

33. 2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl]piperidin-1-yl]methyl]-3-[[(2s)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic Acid

34. 2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy}pyridin-2-yl)piperidin-1-yl]methyl}-1-[(2s)-oxetan-2-ylmethyl]-1h-benzimidazole-6-carboxylic Acid

2.4 Create Date
2018-06-23
3 Chemical and Physical Properties
Molecular Weight 555.6 g/mol
Molecular Formula C31H30FN5O4
XLogP31.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area114
Heavy Atom Count41
Formal Charge0
Complexity941
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 2230198-02-2 / Danuglipron API manufacturers, exporters & distributors?

Danuglipron manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Danuglipron API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Danuglipron manufacturer or Danuglipron supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Danuglipron manufacturer or Danuglipron supplier.

PharmaCompass also assists you with knowing the Danuglipron API Price utilized in the formulation of products. Danuglipron API Price is not always fixed or binding as the Danuglipron Price is obtained through a variety of data sources. The Danuglipron Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Danuglipron

Synonyms

Pf-06882961, 2230198-02-2, Danuglipron [usan], Dn9iui24gp, (s)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1h-benzo[d]imidazole-6-carboxylic acid, 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2s)-oxetan-2-yl]methyl}-1h-benzimidazole-6-carboxylic acid

Cas Number

2230198-02-2

Unique Ingredient Identifier (UNII)

DN9IUI24GP

About Danuglipron

PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).

2230198-02-2 Manufacturers

A 2230198-02-2 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 2230198-02-2, including repackagers and relabelers. The FDA regulates 2230198-02-2 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 2230198-02-2 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of 2230198-02-2 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

2230198-02-2 Suppliers

A 2230198-02-2 supplier is an individual or a company that provides 2230198-02-2 active pharmaceutical ingredient (API) or 2230198-02-2 finished formulations upon request. The 2230198-02-2 suppliers may include 2230198-02-2 API manufacturers, exporters, distributors and traders.

click here to find a list of 2230198-02-2 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

2230198-02-2 GMP

2230198-02-2 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 2230198-02-2 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 2230198-02-2 GMP manufacturer or 2230198-02-2 GMP API supplier for your needs.

2230198-02-2 CoA

A 2230198-02-2 CoA (Certificate of Analysis) is a formal document that attests to 2230198-02-2's compliance with 2230198-02-2 specifications and serves as a tool for batch-level quality control.

2230198-02-2 CoA mostly includes findings from lab analyses of a specific batch. For each 2230198-02-2 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

2230198-02-2 may be tested according to a variety of international standards, such as European Pharmacopoeia (2230198-02-2 EP), 2230198-02-2 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (2230198-02-2 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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