Find AKV9 manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Nu-9, Akv9, Ssz5c8u4kq, Akv-9, Chembl2089305, Schembl12676303
Molecular Formula
C16H14F6O3
Molecular Weight
368.27  g/mol
InChI Key
FVEVQUBFQXFSNY-QMMMGPOBSA-N
FDA UNII
SSZ5C8U4KQ

AKV9
1 2D Structure

AKV9

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]cyclohexane-1,3-dione
2.1.2 InChI
InChI=1S/C16H14F6O3/c1-8(9-2-12(23)7-13(24)3-9)25-14-5-10(15(17,18)19)4-11(6-14)16(20,21)22/h4-6,8-9H,2-3,7H2,1H3/t8-/m0/s1
2.1.3 InChI Key
FVEVQUBFQXFSNY-QMMMGPOBSA-N
2.1.4 Canonical SMILES
CC(C1CC(=O)CC(=O)C1)OC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F
2.1.5 Isomeric SMILES
C[C@@H](C1CC(=O)CC(=O)C1)OC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
SSZ5C8U4KQ
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Nu-9

2. Akv9

3. Ssz5c8u4kq

4. Akv-9

5. Chembl2089305

6. Schembl12676303

7. Fvevqubfqxfsny-qmmmgpobsa-n

8. 1,3-cyclohexanedione, 5-[(1s)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]-

9. 5-[(1s)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]-1,3-cyclohexanedione

10. 1307262-15-2

2.4 Create Date
2013-02-04
3 Chemical and Physical Properties
Molecular Weight 368.27 g/mol
Molecular Formula C16H14F6O3
XLogP33.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count9
Rotatable Bond Count3
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area43.4
Heavy Atom Count25
Formal Charge0
Complexity475
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

Drugs in Development

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Details:

The funding will support Akava’s lead compound, NU-9 (AKV9). It is being evaluated for the treatment of Alzheimer’s disease and frontotemporal dementia.


Lead Product(s): AKV9

Therapeutic Area: Neurology Brand Name: NU-9

Study Phase: IND EnablingProduct Type: Other Small Molecule

Sponsor: National Institute on Aging

Deal Size: $7.3 million Upfront Cash: Undisclosed

Deal Type: Funding December 17, 2024

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01

Simposio AFI
Not Confirmed
Simposio AFI
Not Confirmed

Details : The funding will support Akava’s lead compound, NU-9 (AKV9). It is being evaluated for the treatment of Alzheimer’s disease and frontotemporal dementia.

Product Name : NU-9

Product Type : Other Small Molecule

Upfront Cash : Undisclosed

December 17, 2024

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Details:

AKV9 (formerly NU-9) is a Protein aggregation inhibitor, which is being investigated in amyotrophic lateral sclerosis and improve the health of diseased upper motor neurons.


Lead Product(s): AKV9

Therapeutic Area: Neurology Brand Name: AKV9

Study Phase: IND EnablingProduct Type: Other Small Molecule

Sponsor: Inapplicable

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable August 22, 2023

blank

02

Simposio AFI
Not Confirmed
Simposio AFI
Not Confirmed

Details : AKV9 (formerly NU-9) is a Protein aggregation inhibitor, which is being investigated in amyotrophic lateral sclerosis and improve the health of diseased upper motor neurons.

Product Name : AKV9

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

August 22, 2023

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ABOUT THIS PAGE

Looking for 1307262-15-2 / AKV9 API manufacturers, exporters & distributors?

AKV9 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of AKV9 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right AKV9 manufacturer or AKV9 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred AKV9 manufacturer or AKV9 supplier.

PharmaCompass also assists you with knowing the AKV9 API Price utilized in the formulation of products. AKV9 API Price is not always fixed or binding as the AKV9 Price is obtained through a variety of data sources. The AKV9 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

AKV9

Synonyms

Nu-9, Ssz5c8u4kq, Akv-9, Chembl2089305, Schembl12676303, Fvevqubfqxfsny-qmmmgpobsa-n

Cas Number

1307262-15-2

Unique Ingredient Identifier (UNII)

SSZ5C8U4KQ

1307262-15-2 Manufacturers

A 1307262-15-2 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 1307262-15-2, including repackagers and relabelers. The FDA regulates 1307262-15-2 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 1307262-15-2 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

1307262-15-2 Suppliers

A 1307262-15-2 supplier is an individual or a company that provides 1307262-15-2 active pharmaceutical ingredient (API) or 1307262-15-2 finished formulations upon request. The 1307262-15-2 suppliers may include 1307262-15-2 API manufacturers, exporters, distributors and traders.

1307262-15-2 GMP

1307262-15-2 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 1307262-15-2 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 1307262-15-2 GMP manufacturer or 1307262-15-2 GMP API supplier for your needs.

1307262-15-2 CoA

A 1307262-15-2 CoA (Certificate of Analysis) is a formal document that attests to 1307262-15-2's compliance with 1307262-15-2 specifications and serves as a tool for batch-level quality control.

1307262-15-2 CoA mostly includes findings from lab analyses of a specific batch. For each 1307262-15-2 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

1307262-15-2 may be tested according to a variety of international standards, such as European Pharmacopoeia (1307262-15-2 EP), 1307262-15-2 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (1307262-15-2 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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